경피 전달을 위한 palmitoyl-KTTKS의 최적처방

• 영문명: Optimal Formulation of palmitoyl-KTTKS for Transdermal Delivery
• 발행기관: 대한약학회
• 저자명: 이규진(Kyu-jin Lee) 최윤림(Yun-lim Choi) 신영희(Young-hee Shin)
• 간행물 정보: 『약학회지』제61권 제2호(2017년), 96~99쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2017.04.30

영문 초록

Palmitoyl KTTKS (Pal-KTTKS), a derivative of KTTKS has been known for better skin penetration to stimulate skin matrix replenishment through topical application. The main purpose of this study was to find the opitmal formulation of pal-KTTKS for transdermal delivery. In this study, three kind of formulaion - hydrophilic, hydrophobic and emulsion formualtion were examined. On in vitro retention study, pal-KTTKS was retained with higher amount in stratum corneum than viable layer. The higher retention rate of pal-KTTKS was observed in the emulsion formulation than others.

목차

재료 및 방법

실험결과 및 고찰

결 론

References

키워드

palmitoyl-KTTKS in vitro retention optimal formulation