구강암 환자에서 방사선 조사에 따른 타액의 세균학적 조성변화에 대한 연구

• 영문명: THE CHANGES OF SALIVARY MICROORGANISM COMPOSITION AFTER THERAPEUTIC RADIATION FOR ORAL CANCER PATIENTS
• 발행기관: 대한구강악안면외과학회
• 저자명: 이종호(Jong Ho Lee) 김명진(Myung Jin Kim) 정필훈(Pill Hoon Choung) 최진영(Jin Young Choi) 서병무(Byoung Moo Seo) 송노헌(Ro Heun Song) 안강민(Kang Min Ahn) 김종원(Jong Won Kim) 남일우(Il Woo Nam) 김수경(Soo Kyung Kim)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제26권 제1호, 18~23쪽, 전체 6쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2000.02.28

영문 초록

The changes of the microorganism composition after therapeutic radiation for oral cancer patients are not well known and the longterm follow-up data are not reported. To obtain basic data for understanding of pathogenesis and prevention and treatment of dental caries and mucositis occuring after radiation therapy, 7 of the oral cancer patients presented at the Seoul National University Oral & Maxillofacial Department between 1997 and 1998 whose treatment plan included radiation therapy were recruited to investigate the changes in bacterial composition(total aerobic count, Candida, Staphylococci, Lactobacilli, S.mutans, and S.salivarius(mitis, sanguis)) of the saliva before, during, and after radiation therapy. The basic data obtained from this study on identification and composition change of the bacteria in saliva of patients treated with radiation therapy can be used (1) as a reference for deciding on the ideal anti-microbial spectrum of the oral rinsing agent to be used in patients treated with radiation therapy for malignant tumor of the head and neck region. (2) to enhance the understanding of increase of opportunistic infection after immunochemical changes of the saliva and its relation to specific bacterial infection. (3) as a reference in prescribing prophylactic antibiotics in immunodepressed patients after radiation therapy.

목차

Abstract

Ⅰ. 서론

Ⅱ. 연구재료 및 방법

Ⅲ. 결과

Ⅳ. 총괄

Ⅴ. 요약

참고문헌

키워드

Oral cancer Radiation therapy Saliva Microorganism