한국 성인의 혈청 잔류성 유기오염물질 농도와 연령 및 체질량지수와의 관련성

• 영문명: Association of Persistent Organic Pollutants (POPs) with Age and Body Mass Index in Korean Adults
• 발행기관: 한국환경보건학회
• 저자명: 문호정(Ho Jung Moon) 임정은(Jung-eun Lim) 지선하(Sun Ha Jee)
• 간행물 정보: 『1. 한국환경보건학회지』제40권 제6호, 442~453쪽, 전체 12쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2014.12.30

영문 초록

Objectives: Persistent organic pollutants (POPs) are known to be the detrimental chemicals in the body, even at low levels, and are stored in adipose tissue. Recently, POPs have been reported to be associated with chronic diseases, including cancer and cardiovascular disease, and aging and obesity are reported as common factors in chronic disease. However, there have been only a few studies on the associations of POPs with age and body mass index (BMI) in Korea. Therefore, we analyzed the associations of serum POPs levels with age and BMI in Korea. Methods: This cross-sectional study includes 444 subjects (253 men and 191 women) from the Korean Cancer Prevention Study-II (1994-2011). Serum levels of 33 polychlorinated biphenyls (PCBs) and 19 organochlorine pesticides (OCPs) were measured by a gas chromatographer (Agilent 6890) coupled to high resolution mass spectrometer (JEOL JMS-800D). Results: Concentrations of PCB 153 (men: 12.26 ng/g lipid, women: 10.50 ng/g lipid) and p,p -DDE (men: 94.66 ng/g lipid, women: 96.66 ng/g lipid) were the highest among serum PCBs and OCPs, respectively. PCBs and OCPs were significantly positively correlated with age in both sexes. After adjustment for age, non-dioxin like PCBs were significantly negatively correlated with BMI in women. However, cis-heptachlor epoxide was significantly positively correlated with BMI in both sexes. When analyzed by sex, stronger associations were shown between POPs and age in men and POPs and BMI in women. Conclusion: These results may provide baseline data for the study of POPs and for the health management field in Korea.

목차

I. 서 론

II. 대상 및 방법

III. 결 과

IV. 고 찰

V. 결 론

키워드

Age distribution Body mass Index Organochlorine pesticides (OCPs) Persistent organic pollutants (POPs) Polychlorinated biphenyls (PCBs)