아토피 아동 가정내 집먼지 진드기 농도와 환경요인:

• 영문명: House Dust Mites and Associated Environmental Factors in Homes of Atopic Children: a Case-Control Study
• 발행기관: 한국환경보건학회
• 저자명: 김성호(Sungho Kim) 박동진(Dongjin Park) 변혜정(Hyaejeong Byun) 이현수(Hyunsoo Lee) 오인보(Inbo Oh) 심창선(Changsun Sim) 김양호(Yangho Kim) 윤충식(Chungsik Yoon)
• 간행물 정보: 『1. 한국환경보건학회지』제38권 제3호, 204~212쪽, 전체 9쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2012.06.30

영문 초록

Objectives: The purpose of this study was to determine house dust mite concentrations in living rooms and bedding materials in atopic case-control groups. Methods: Fifty four homes with children suffering atopic diseases as cases and fifty one homes without atopic diseases as controls were selected after diagnosis at three elementary schools in Ulsan City. Dust samples were collected from the living rooms and bedding materials in each home during summer and winter with a vacuum cleaner and analyzed for house dust mites using enzyme-linked immunosorbent assay (ELISA). Environmental factors and family history were surveyed during sampling. Results: Both species of house dust mite Dermatophagoides farina (Der f 1) and Dermatophagoides pteronyssinus (Der p 1) were found in all homes. Derf1 concentrations were much higher than Der P1 concentrations, both in atopic homes (1518.9 vs. 27.0 ng/g. dust, respectively) and non-atopic homes (810.8 vs. 44.3 ng/g. dust, respectively). Der f 1 concentrations were significantly higher in the atopic group than in the non-atopic group (atopic: 1518.9 ng/g.dust, non-atopic: 810.8 ng/g.dust, p = 0.035). However, total house dust mite Der p 1 concentrations were significantly higher in the non-atopic group than in the atopic group (atopic: 27.0 ng/g.dust, non-atopic: 44.3 ng/g.dust, p = 0.035). Multiple regression implied that mothers with family history of atopic diseases (OR = 4.79, 95% CI = 1.81-12.69), Der f 1 concentrations (OR = 1.74, 95% CI = 1.07- 2.81), and air freshener use (OR = 4.60, 95% CI = 1.72-12.34) had significant associations with atopic children. Conclusion: House dust mite Der f 1 concentrations were associated with atopic children. This study suggests that parents should reduce house dust mite Der f 1 concentrations through environmental controls.

키워드

case-control atopic disease house dust mite environmental factor allergen