Sialadenoma papilliferum:

• 발행기관: 대한구강악안면외과학회
• 저자명: June-Ho Byun Dong-Chul Kim Gyung-Hyuck Go Bong-Wook Park
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제36권 제6호, 533~537쪽, 전체 5쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2010.12.30

영문 초록

Sialadenoma papilliferum (SP) is a rare benign neoplasm that normally arises from the minor salivary glands, particularly in the palate. SP is normally encountered in older men with an exophytic papillary surface growth. In the present study, an SP of the hard palate of a 69-year-old woman was examined immunohistochemically. Myoepithelial cell markers, such as S-100, smooth muscle actin and vimentin, were observed in the basal or luminal layer of tumor cells, indicating that myoepithelial cells participate in the pathogenesis of SP. In addition, cytokeratin 7 was also strongly detected in the tumor cells, suggesting that excretory ductal epithelial cells have a role in its histogenesis. A review of the literature of immunohistochemical studies on SP showed that the expression and co-expression of cytokeratins and myoepithelial cell markers have been reported in tumor cells. These results suggested that excretory duct cells and myoepithelial cells participate in the pathogenesis of SP.

키워드

Sialadenoma papilliferum Hard palate Immunohistochemistry