학술논문
DPYD Genetic Polymorphism of Dihydropyrimidine Dehydrogenase (DPD) and Its Possible Implication in Altered 5-Fluorouracil Catabolism
이용수 5
- 영문명
- 발행기관
- 대한약학회
- 저자명
- PARK Hyun-Joo KANG Tae-Sun SHIN Hee-Jung HA Ji-Hey KIM Hae-Deun KIM Young-Hoon NA Han-Sung CHUNG Myeon-Woo
- 간행물 정보
- 『추계총회 및 학술대회』(2010년), 160~160쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2010.10.22
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- Inhibitory Effect against OGD-Inducd Cell Death and ROS Overproduction of 2-Arylbenzofurans from the Root Bark of Morus Species in SH-SY5Y Cells
- Synthesis of a New Class of Trimethoxy-flavone Analogue and Their Anti-atopic Activity
- Dextromethorphan Induces Male Reproductive Toxicity in Mice
- Color Potatoes Extracts Anti-atopic Dermatitis Effects in NC/Nga Mice
- Suppression of Embryonic Stem Cell Signature by Histone Deacetylase Inhibitor in NCCIT Cells
- Efficacy of Combination Therapy of MAb B6.1 Plus Fluconazole to Disseminated Candidiasis
- Synthesis of Homologated 4-Thioadenosine Derivatives as selective Human A3 Adenosine Receptor ligands
- Synthesis of Anthranilamide Derivatives and Histone Acetyltransferase Inhibitory Activity
- Prediction of Human Pharmacokinetics and Tissue Distribution of Apicidin, a Potent Histone Deacetylase Inhibitor, by Physiologically-based Pharmacokinetic Modeling
- Determination of a Dipeptidyl Peptidase IV Agonist, 2-carbonyl-3-acyl-1,3-thiazolidine Derivatives (KR-66223) in Rat Plasma by Liquid Chromatography-tandem Mass Spectrometry
- The Tumor Suppressor Menin Mediates Histone H3 Lysine9 Methylation
- Herceptin-conjugated Immunoliposomes Encapsulating Gemcitabine for Breast Cancer
- Roles of Modification of Chromatin Remodeling Factor in Cancer Development and Metastasis
- Bioavailability of Dimecrotate in Healthy Korean Volunteers
- The Hair Growth Promoting Effect of 4-Omethylhonokiol, a Main Component of Magnolia officinalis
- Isolation of Antioxidant Constituents of Abeliophyllum Distichum by High-Speed Counter-Current Chromatography
- Vascular Smooth Muscle Dysfunction and Remodeling Induced by Ginsenoside Rg3, a Bioactive Component of Ginseng
- Studies on the Synthesis of Schulzeine A and C
- Effects of Folic Acid and Polyethylene Glycol Coated Quantum Dot Nanoparticles on Toxicity and Tissue Uptake to Precision-cut Spleen Slices of Rats
- BCR Neuronal Rac1 GTPase-Activating Protein and Neuronal Development
- The Influence of Preparation Method and Excipients on the Stability of Pramipexole Dihydrochloride Monohydrate Tablets
- A Role of Nrf2 Signaling in Angiotensin II-Induced Kidney Fibrosis
- Protective Effects of Some Compounds from Amorpha fruticosa L Against Dopamine-induced Cell Death on SHSY5Y Neuroblastoma Cells
- Dose Adjustment of Omeprazole Based on CYP2C19 Genotype in Healthy Koreans
- Simultaneous Analysis for Six Synthetic Compounds added to Dietary Supplements Using Ultra Performance Liquid Chromatography Coupled with Quadrupole-Time of Flight Mass Spectrometry (UPLC-Q-TOF MS)
- Developments of Novel Neuroprotective Agents (YJC or YJP Series) Against Alzheimer's and Parkinsonian Conditions
- Sensitive Staining of Proteins on Sodium Dodecyl Sulfate Polyacrylamide Gel for Proteomic Analysis
- Compound K, a Metabolite of Ginsenoside Rb1, Inhibits the Key Step of Inflammation, IRAK-1 Activation
- In vitro and in vivo Osteogenesis and Neurogenesis of Porcine Mesenchymal Stem Cells
- The Roles of RECK in Cancer Progression and Mammalian Ddevelopment
- Innate Immune Mechanisms of Vaccines
- Targeting Host-tumor Interaction as Novel Anti-tumor and Anti-Metastatic Strategy
- Total Synthesis of Biologically Active Terpenoids and Meroterpenoids
- Melatonin Protects Liver against Ischemia and Reperfusion Injury by Inhibiting Toll-like Receptor 3 and 4 Overexpression
- Decoding Cancer Signature: Systems Biology Approaches
- An Evaluation of the Impact of Oral Magnesium Lactateon the Corrected QT Interval of Patients Receiving Sotalol or Dofetilide to Prevent Atrial or Ventricular Tachyarrhythmia Recurrence
- Profiling Genotype-Dependent Drug Sensitivity in Cancers
- Metabolomics Approach for Discovering Drug Response and Disease Biomarkers
- 6-Shogaol, a Pungent Ingredient of Zingiber officinale Roscoe, Attenuates Neuronal Damage in Neurodegenerative Disease Models
- Inhibition of Triglyceride Synthesis as a Treatment Strategy of Metabolic Disorders
- Protective Effects of Mg-CUD against D-galactosamine-induced Hepatotoxicity in Rats
- Enhanced Nrf2-Regulated Gene Expression by Keap1-Knockdown System in Human Colon Cancer Cells
- Effects of Gastrodia elata Extracts on the Metabolism of Amyloid Precursor Protein
- Cytotoxic Effects of Stem Bark Extracts from Lindera obtusiloba on MCF-7 Human Breast Cancer Cells
- Prediction of Pharmacokinetic Profile of Doxifluridine and Its Metabolites, 5-Fluorouracil and 5-Fluorouridine, in Human Using Pharmacokinetic Model in Beagle Dogs
- Anticonvulsant Effect of Artemisia Capillaris Herba in Mice
- A Hypoxia-inducible Factor-1α is Critical for Stress Hormone-induced Angiogenesis
- N-Acetyltransferase-2 (NAT2) Gene Polymorphisms and Enzyme Activity in Korean and Four Other Ethnics
- The Protective Effects of Extracts from Rumex Aquaticus Herba on Rat Reflux Esophagitis Model
- Dinitrochlorobenzene Induces Apoptosis in Human Osteosarcoma MG63 Cells
- Effects of HSP Inhibitor KNK 437 and Quercetin on the Metabolism of Amyloid Precursor Protein
- Compare of Biological Activities with Water and Ethanol Extracts from Leaves of Crossbreed of Ligularia fischeri var. spiciformis and Ligularia stenocephala
- Ethanol Extract of Crysanthemi Flos Augments Pentobarbital-induced Sleep Behaviors through the Modification of GABAergic Systems
- Mechanisms for Anti-inflammatory Actions of 1-[15(S)-hydroxyeicosapentaenoyl] Lysophosphatidylcholine, Administrated Intraperitoneally, in Zymosan A-induced Peritonitis
- Implication of Interleukin-17A and 17F in Human Metabolic Diseases
- Injectable Formulation of YY-1224 Ameliorated Cognitive Impairments Induced by β-Amyloid (1-40) in Mice
- Platycodin D Inhibits Lipogenesis and Lipid Accumulation in the Livers of High-Fat Diet-Induced Obese Mice
- Role of SAM Increase in Tamoxifen-Resistant Breast Cancer Cells
- Allicin Induces Apoptosis in Human Breast Cancer Cells through ROS/MAPKs Pathways
- Anti-allergic Effects of the Compounds from Thujopsis dolabrata by Inhibition of IL-4 in RBL-2H3 Cells
- Neuroprotective Effects of Eucommia Ulmoides Oliver Bark on Cognitive Deficit and Neuronal Cell Death
- A Helicobacter pylori Proinflammatory Protein Up-regulates NF-κB as a Cell-translocating Ser/Thr Kinase
- Modulation of GABAA Receptors Mediates the Effect of MDL72222, the 5-HT3 Antagonist, on Methamphetamine-Induced Conditioned Place Preference
- Adrenergic Receptors are Required for Stress Hormone-induced Angiogenesis
- Conditioned Place Preference to and Self-administration of Stimulant ADHD therapeutics in Spontaneously Hypertensive rats (SHR)
- Development of the Dissolution Test for Viquidil Hydrochloride Capsules
- DPYD Genetic Polymorphism of Dihydropyrimidine Dehydrogenase (DPD) and Its Possible Implication in Altered 5-Fluorouracil Catabolism
- Hypnotic Effects of Apigenin Isolated from Cirsium japonicum: Involvement of GABA/benzodiazepine Receptors Cl- Channel Complex
- Asymmetric Synthesis of D- and L-Ribo-Phytosphingosine
- Antioxidant Activity of Ethyl Acetate Fraction from the Methnoal Extract of L. tulipifera
- Three Main Mechanisms and Medication of Osteoporosis
- An Ameliorating Effect of a Herbal Medicinal Prescription, Kyung-Ok-Ko, on Scopolamine or Transient Forebrain Ischemia-Induced Memory Impairment in Mice
- Therapeutic and Preventive Strategies for the Management of Inflammation-Associated Cancer
- How to Increase the Market Share of Korean Traditional Herbal Products
- The Role of Synthetic Triterpenoids in BRCA1-Mutated Breast Cancer
- Cell Migration and Invasion via a TM4SF5-FAK Signaling Linkage
- Regulation of Breast Cell Invasion by Ras Isoform-Specific Signaling
- Heat Shock Protein ClpL Increases Penicillin Resistance by Inducing PBP2X in Streptococcus Pneumoniae
- Toward Individualized Immunosuppressive Therapy for Korean Living-Donor Liver Transplant Recipients
- Natural Products: Challenges and Opportunities
- Identification and Clinical Validation of Claudin-3 and Claudin-4 as Anti-Cancer Targets
- Total Synthesis of Bioactive Alkaloids via Aza-Claisen Rearrangement
- Fluorescent Phosphoinositide 3-Kinase Inhibitors Suitable for Monitoring of Intracellular Distribution by Fluorescence Microscopy
- A Prognostic Model for Early Breast Cancer Patients by Integrating Proliferation and Immune Response
- YH11250, a Novel LXR Agonist, Promotes Reverse Cholesterol Transport and Raises Serum HDL-cholesterol Level without Hepatic Lipogenesis
- 6년제 약대 실무교육강사 양성방안
- Gliclazide Pharmacokinetics in Relation to CYP2C19 Genotype in Healthy Koreans
- Influence of ABCB1 C3435T Polymorphism on the Pharmacokinetics of Ezetimibe and Its Glucuronide in Healthy Subjects
- An Effect of Rare Earth Elements Water on Atpic Dermatitis
- CYP2D6 Genetic Polymorphism Has an Impact on the Pharmacokinetics of Carvedilol in Korean Subjects
- Inhibition of NRF2 Expression in Colon Cancer Cells Suppresses HIF-1α Signaling
- Anti-inflammatory Effects of Tyrosine-fructose Maillard Reaction Product, 2,4-bis(p-hydroxyphenyl)-2-butenal In Vitro and In Vivo
- Piceatannol Attenuates TPA-induced Expression of COX-2 and iNOS in HR-1 Hairless Mouse Skin by Inhibiting NF-κB and AP-1 Activation through the Modulation of IκB kinase-β and MAP Kinases
- Effect of IN-1130, an ALK5 Inhibitor on Lung Metastasis of Breast Cancer In Vivo
- Comparison of Losartan- and Enalapril-Induced Inhibitory Effects on Adrenal Catecholamine Release
- The Establishment of a Secondary Korean National Standard of Blood Coagulation Factor VIII: C Concentrate for Potency Test
- Inhibition of Tumor-Associated Angiogenesis by a Novel Hexahydrocannabinol Analog
- Sedative Effects of Cimicifuga Rhizoma
- CAPE Reduced the Expression of Cyclin D1 and VRK 1 in Breast Cancer
- Effects and Mechanisms of Free Fatty Acidsinduced Steatosis in HepG2 Cells
- Rh2(S)-Induced PKD Activation Induce the Mineralization of Osteoblastic MC3T3-E1 Cells through AMPActivated Protein Kinase and p38 Activation
- The Effect of Dieckol, a Component from Ecklonia cava, on the Promotion of Hair Growth
- In Vitro Antioxidant and Anticancer Activities of Stem Barks Extracts of Euonymus Macroptera
- 4-O-methylhonokiol Prevents Lipopolysaccharideinduced Elevation of Beta-amyloid Generation and Memory Deficiency
- Mutation of Presenilin 2 Inhibits Lung Tumorigenesis through Inhibition of Peroxiredoxin-6 Expression
- Purple Sweet Potato Anthocyanins Reduce Reactive Oxygen Species Generated by Excitotoxic Insults in the Primary Cultured Rat Cortical Cells
- Inhibition of Hinokitiol to Cell Proliferation in Human Colon Carcinoma Cells through S-phase Arrest
- Inhibitory Effect of Hinokitiol on Adipogenesis in 3T3-L1 Preadipocytes
- Antioxidant Activities and Flavonoids Content of Water and Ethanol Extracts from Leaves of Crossbreed of Ligularia fischeri var. spiciformis and Ligularia stenocephala
- 4-Chloro-7-Trifluoromethyl-10H-Benzo[4,5]furo [3,2-b]Indole-1-Carboxylic Acid, a Putative BKCa Channel Opener with Tocolytic Activities
- (-)-Epigallocatethin-3-O-gallate (EGCG) Augments Pentobarbital-induced Sleep Behaviors through the Modification of GABAergic Systems
- Neuropilin-1 Reduce TNF-α-Induced MMP-9 Expression via NF-kB Signaling in HT1080, Human Fibrosarcoma Cells
- Inhibitory Activity of Allium microdictyon leaves on Lipopolysaccharide (LPS) Lnduced Nitric Oxide Production on RAW 264.7 Cell Line
- RORα Regulates Profibrogenic Genes and Migration
- Effects of Chaga Mushroom(Inonotus Obliquus) Extracts on the Production of Cytokines in RBL-2H3 Cells, EL-4 T Cells, OVA-sensitized CD4+ T Cells and Raw 264.7 cells
- Determination of a 5HT2C Agonist, KOPC-200105 (KP10), in Rat Plasma and Urine by Gas-Chromatography/Mass Spectrometry and Its Pharmacokinetics in Rats
- An Inference of Driving Under the Influence of Drugs in Metropolitan Area of Korea
- Interleukin-22 Treatmnet Improves Alcoholic Liver Injury
- Modulation of Oxidative Stress and Inflammation by Gravinol in High Glucose-exposed Renal Tubular Epithelial Cells
- Cytotoxic Effects of Arbutin and Its Metabolites in Human Hepatoma Cells
- Changes in Plasma Homocysteine Levels in db/db Mice
- Menadione Serves as a Substrate of P-glycoprotein: Implication in Synergism with Cancer Chemotherapeutics Subject to Drug Resistance
- Metabolism of Anti-Inflammatory Propenone Compounds
- Molecular Mechanism of Endothelial Nitric-Oxide Synthase Activation by Puerarin
- Genetic Modifier of Mitochondrial Superoxide Dismutase Deficient Mice Delays Heart Failure and Prolongs Survival
- Solubilized Single-Walled Carbon Nanotube (SWCNT) Induces Cell Growth Inhibition and Apoptosis via DNA Damage in Normal Rat Kidney Epithelial Cells
- MT-2A Overexpression Increases the Expression of MMP-9 and Invasion of Breast Cancer Cells
- Safety Evaluation of Herbal Medicines: Procoagulant Activation by Herbal Extracts in Platelets
- The Role of Oxidative Stress in Silver Nanoparticles-Induced Genotoxicity of Human Normal Lung (BEAS-2B) Cells
- Integrating of Studies Regarding Non-genotoxic Compounds using Open-source Software
- Effect of Metabolism by Intestinal Microfloraon Phamacokinetics of Baicalin, in vivo
- Characterization of Estrogenic Effects of Active Compounds from River Water Using GC-analysis and Invitro Bioassay
- Agonist-Dependent Activity of TRPA1 Ion Channel is Inhibited by Gabapentin
- Effect of Recombinant Human Granulocytemacrophage Colony Stimulating Factor (rhGM-CSF) on 5-FU Induced Oral Mucositis in Hamsters
- FB1 Induce Upregulation DHS1P and Stimulated MMP1 Expression in Human Dermal Fibroblasts
- Effect of Sulforaphane-containing Broccoli Extract on Anti-inflammation
- Arbutin Inhibits TCCSUP Human Bladder Cancer Cell Proliferation via Up-regulation of p21
- Expression of CYP2A6, CYP4A11 and CYP2D6 Polymorphisms in Mammalian Cell Line
- The Sesquiterpene Zerumbone Induces Heme Oxygenase Expression in Mouse Skin and Cultured Murine Epidermal Cells Through Activation on Nrf2
- Cordlan Polysaccharide Isolated from Mushroom Cordyceps militaris Induces Dendritic Cell Maturation through Toll-Like Receptor 4 Signalings
- Screening of Radical Scavenging Activity of Several Formulae
- Differential Impacts of IGFBP-3 in Epithelial IGFinduced Lung Cancer Development
- DNA Methylation Regulates Metastasis-Associated Protein 1 Gene Expression in Human Liver Cell Lines
- Anticancer Effects of Taurine in Human Breast and Cervical Cancer Cells
- Cloning, Expression and Purification of Tomato Methionine Sulfoxide Reductase (MSR) Gene
- Torilin from Torilis japonica Inhibit Melanogenesis through the Degradation of MITF by Rsk-1 Activation in B16 Melanoma Cells
- Glycoside-Hydrolyzing Enzyme Activities of Intestinal Bacteria Isolated from Koreans
- Enhancement of Immune Responses after Intramuscular Immunization with Protein and DNA Combination Vaccine using Maltosylated Polyethylenimine
- KLF5 is a Positive Regulator of TNF-α Induced VCAM-1 Expression
- Anti-MSSA and MRSA Activities of Caffeoyl Derivatives from the Leaves of Ilex rotunda
- Synthesis of 4’-Thio-AZT Derivatives as Potent Anti-HCV Agents
- Inhibition of LPS/IFN-γ-Induced NO Production by Edible Yam Extracts (H1) via Suppression of MAPK/NF-κB Pathways in Macrophages
- Virtual Screening and Synthesis of Quinazolines as Novel JAK2 Inhibitors
- Antimicrobial Activities of a Lipopeptide Derived from Bacillus Mojavensis KJS-3
- Stereoselective Synthesis of 3’-Amino-carbanucleoside Derivatives as A3 Adenosine Receptor Ligands
- Synthesis and Evaluation of Cinnamoyl Keto-Amides for Calpain Inhibitory Activities
- New Scalarane Sesterterpenes from the Sponge Hyatella sp.
- Simulation and Docking Analysis of G-protein Coupled Receptor 119, a Potential Target for the Treatment of Diabetes and Obesity
- Sesterterpene Sulfates from the Tropical Sponge Dysidea sp.
- Synthesis and Evaluation of Decursidin Analogues as Inhibitor of the Wnt Signaling
- Over-expression of Skp2 is Associated with Cisplatin Resistance in Human Gastric Cancer Cell
- Synthesis of Sulfonamide-substituted Flavones and Their Biological Activities
- Anti-inflammatory Diterpene from Thyrsanthera suborbicularis Collected in Cambodia
- Concise Total Synthesis of (+)-Epiquinamide
- Tyrosinase Inhibitory Constituents from the Cortex of Morus bombycis
- Gentisic Acid Esters as Putative Skin-lightening Agents : Evaluation of Their Tyrosinase and Melanocyte Inhibition and Skin Permeation
- Benzothiazole-based Inhibitors of NO Production in LPS Activated Macrophages
- Optimal Condition for Alkylthiolation and Synthesis of New 3-Allylseleno-6-alkylthiopyridazines
- Effects of Ethanol Extract from the Unripe Fruit of Rubus coreanus on Penile Erection
- Synthesis and Anti-Ischemic Activity of Norlignan Derivatives LMTs
- Selective Inversion of the Hydroxyl Group in D-ribo-Phytosphingosine for the Synthesis of Its Stereoisomers
- Design and Synthesis of Novel Bromo-retrochalcone Derivatives as PTP1B Inhibitors
- Salicylic Acid Derivatives for Inhibition of TNF-α Dependent NFκB Activity: Structural Analysis and Antiinflammatory Effect
- Current Safety of Ssam Vegetables by Survey and Pesticide Residues for Agricultural Produts in Gangseo Area
- Evaluation of Genotoxic Effects of Particulate Matters (PM10) Collected from Subway
- Development of Simultaneous Quantification Method for Determining Psychotropic Phenylalkylamines Levels in Oral Fluid
- Role of Metabolism by Intestinal Bacteria in Arbutin-Induced Toxicity in vitro
- The Role of p53 in MSC Extract Induced Cellular and Molecular Responses Associated with Lung Carcinogenesis
- Effects of Ethanol Extracts of 16 Herbs on Cytochrome P450-Associated Monooxygenase Activities in Enriched Rat Liver Microsomes
- Cytotoxic Effects of Geniposide and Its Metabolites in Cells
- Assessment of Bisphenol A Exposure in Korean Pregnant Women by Physiologically-Based Pharmacokinetic Modeling
- Inhibitory Effects of Acrolein-Stimulated MUC5AC Production by Platycodon Grandiflorum Root-derived Saponins in A549 Cells
- Dietary Anthocyanin-Rich Purple Sweet Potato Extract Ameliorates Hyperglycemia and Insulin Sensitivity via Activation of AMP-Activated Protein Kinase in Human HepG2 Cells
- Translationally Controlled Tumor Protein Overexpression Induced Hypertension Increases Aherosclerotic Lesion on High Fat Fed ApoE Knock out Male Mice
- In Vitro Screening of NADPH Oxidase Inhibitors and its Effects to EAE-Induced Mice
- Low-level Mercury Can Enhance Procoagulant Activity of Erythrocytes: A New Contributing Factor for Mercury-related Thrombotic Disease
- A Mevalonate Pathway Metabolite Activates a Skin Keratinocyte Ion Channel Leading to Pain
- Translationally Controlled Tumor Protein Induces Human Breast Epithelial Cell Transformation through the Activation of Src
- UVB-activated Indole-3-Acetic Acid Induces Apoptosis of PC-3 Prostate Cancer Cells
- Yam Bark Extracts (H2) Suppresses LPS/IFN-γ-Induced NO Production by MAPKs and NF-κB in Activation in Raw 264.7 Macrophages
- A Potential Role of Upstream Signaling for the Regulation of Tumor Suppressor Menin
- Novel Chalcone (JSH 03-1-10) Prevents NF-kB Activation by Inhibiting TAK1 in LPS-avtivated Macrophages
- Cdo Binds Abl to Promote p38MAPK Activity and Myogenic Differentiation
- The Effects of Sulforaphane and Propolis on Anti-Inflammation and Anti-Oxidation
- Prunella vulgaris L. Attenuates Disruption of Prepulse Inhibition of Sensorimotor Gating Deficits in Mice
- Rhododendrin, an Analgesic/anti-inflammatory Arylbutanoid Glycoside from the Leaves of Rhododendron aureum Georgi
- Chemical Constituents from Radix of Chamaecyparis obtusa
- Three New Asterosaponins Isolated from the Starfish Asterias amurensis
- Effect of Quercetin 4’-O-β-D-Glucopyranoside from Dried Skin of Red Onion (Allium cepa) in Mushroom Tyrosinase
- Phenolic Constituents from the Hylomecon vernalis
- Antiobesity Mechanism Effects of Boussingaultia gracilis Miers ver
- Diospyros kaki Inhibits Mast Cell-Mediated Allergic Reactions through the Inhibition of Histamine Release and Inflammatory Cytokine Production
- Medicinal Herbal Combination Improves Obesity via Neuroendocrine Modulation in Rats Fed High-fat Diet
- Metabolism of Ginsenoside Rb1 by Korean Microflora
- Isolation of Compounds from Scilla sinensis Merr.
- Studies on the Effects of Age of Dermatophagoides farinae (Df) Inducing Atopic Dermatitis in NC/Nga Mice
- Diallyl Trisulfide Induces Heme Oxygenase-1 and NAD(P)H:Quinone Oxidoreductase 1 through Activation of Nuclear Factor E2-Related Factor2 Signaling in Mouse Stomach and Human Gastric Epithelial Cells
- Epigenetic Regulation of Nanog Expression in NCCIT Cells
- Anti-Allergic Activity of the Rhizomes of Rheum tanguticum (rhubarb) and Its Major Constituents
- Ying Yang1 Decreases Cyclooxygenase-2 Gene Expression via Regulates NFATc1
- Silibinin Inhibits Helicobacter pylori-Induced Activation of NF-κB and STAT3 in Cultured Human Gastric Cancer Cells and in C57BL/6 Mouse Stomach in vivo
- A Newly Synthesized Strong Tyrosinase Inhibitor : MHY-C
- Role of PKC in Epigenetic Regulation of Gelsolin Expression by Histone Deacetylase Inhibitor, Apicidin
- Inhibitory Effect of Bisabolangelone on Melanogenesis by Down-Regulating MITF Expression in Alpha-MSHInduced B16 or Melan-a Cells
- A Drug Interaction: Chlorogenic Acid, a Polyphenolic Compound, Causes Reverse Antifungal Effect upon Combination with Amphotericin B
- Development of 2’-Fluoro-4’-selenonucleosides as Potent Anticancer Agents
- A Cold Adaptive Acidophilic Lipase from Streptomyces
- Synthesis of Pyrrole [2,3-d] Pyrimidines as CBR1 Inhibitors
- Artesunate Inhibits Proliferation of Naive CD4+ T Cells and Enhances Function of Th1/Th2 Cells
- Bamboo Culm Extract Attenuates Early Development of Systemic Inflammation in Pristane-Primed Lupus Mice
- Antibacterial Effects of Honokiol and Magnolol from Magnolia officinalis
- Anti-obesitic Effect of Phenolic Fractions from Geranium nepalense subsp. thunbergii (S. et Z.) Hara
- Synthesis and Evaluation of Bioconjugate Using Coumarin Isothiocyanate as the Potential Fluorescent Compound for the Detection of Specific Antigen
- Biological Activity and Total Synthesis of Novel 2'-Oxabicyclo[3.1.0]hexyl Nucleosides Fixed with a North Conformation
- Design and Synthesis of Unnatural Novel C-NH-C Linked Biflavones
- Synthesis and Antioxidant Effect of Caffeic Acid Analogues Bearing a Carboxyl and Hydroxymethyl Group
- Sulfate Conjugation of Metronidazole Delivers the Antiamebic Agent Specifically to the Large Intestine
- Synthesis and Antifungal Evaluation of Furo[2,3-f]quinolin-5-ols
- Megastigmane Glucosides from Pleurospermum camtschaticum
- Inhibition of -1 Ribosomal Frameshifting in SARS Coronavirus by Homopiperazinyl Thiazolyl Ketone Derivatives
- Synthesis and Antifungal Activity of 4-Arylthio-5-hydroxybenzofurans
- A Concise Total Synthesis of 4-O-Methylhonokiol
- Design and Synthesis of Unnatural Novel Biflavone Having C-S-C Linkage
- Structural Insights of TRPV1 from Homology Modeling, Flexible Docking, and Mutation Studies for the Discovery of TRPV1 Modulators
- 3, 4-Dihydroquinazoline-2(1H)-thiones as Melanogenesis Inhibitor: SAR and Refinement of the Pharmacophore
- Synthesis and Anticoagulant Activity of Anthranilic Acid Derivatives
- Total Synthesis of D-xylo- and D-arabino-Phytosphingosine
- Growth Inhibition and Suppression of Multidrug Resistance Gene Expression by a Novel (-)-Antofine Analog in Paclitaxel-resistant Human Lung Cancer Cells
- Species Identification of Papaver by Metabolite Profiling
- The Method to Simultaneously Evaluate Antidiabetic and Anti-obese Candidates with the Adipogenesis Model of Human Mesenchymal Stem Cells
- Anti-inflammatory Lignans from Magnolia fargesii
- Phenolic Compounds from the Whole Plant of Thlaspi arvense L.
- Phenolic Constituents of Acorus gramineus Soland
- Chemical Constituents from the Flowers of Echinopsis eyriesii (Turp.) Zucc. and their Anti-inflammatory Activity
- Anticnacer Constituents from the Aerial Part of Selaginella tamariscina
- Effects of Ligusticum chuanxiong Essential Oil Fraction and Its Main Components on Proinflammatory Mediator of RAW264.7
- HIV-1 Protease Inhibitory Principles of Uncaria rhynchophylla Hooks
- Antifibrotic Compounds Isolated from the Bark of Alnus firma in HSC-T6 Cells
- Ketoconazole-induced Testicular Damage in Rats Reduced by Cornus officinalis Complex(COC)
- Anti-proliferative Activity of Chrysophanol-8-O-β-glucopyranoside from Rheum tanguticum in HCT 116 Human Colon Cancer Cells
- Tirucallane Triterpenoids from Cornus walteri
- Effects of CMH002 Against H2O2 Induced Toxicity in the HaCaT Cells
- Constituents with DNA Topoisomerase I and II Inhibitory Activity and Cytotoxicities from Euonymus alatus
- Melanogenesis Inhibitory Bisabolane Type Sesquiterpenoids from Angelica koreana
- Study on the Analytical Method of Phamacopuncture of Mahwangcheono and Spdam By Gas Chromatography/Mass Spectrometry
- Anti-Metastatic Properties of the Leaves of Eriobotrya japonica
- Simultaneous Analysis of Non-water-soluble Herbicides
- Simultaneous Determination of Glimepiride and Metformin in Human Plasma by LC-MS/MS Method : Application to a Pharmacokinetic Study in Healthy Korean Volunteers
- Validation of a Dissolution Method with HPLC Analysis for Caroverine Tablets
- Comparison of Liquiritin and Liquiritigeninin in Licorice by High Performance Liquid Chromatography
- Determination of Some Steroid Hormones in Cosmetics
- Arsenic, Cadmium, Lead and Mercury in Medicinal Herbs Used in Seoul Area
- Determination for a Quantitative Analytical Method of Itopride in Human Plasma by LC/MS/MS and the Pharmacokinetic Profiles in Healthy Male Korean Volunteers
- Preparative Isolation and Purification of Seven Isoflavones from Belamcanda Chinensis
- Studies on the Establishment of Methods for Analysis of N-Glycan in Recombinant Products
- Doxorubicin Release from Core-shell Type Nanoparticles of Deoxycholic Acid-Conjugated Dextran
- LC-APCI Tandem Mass Spectrometry for the Simultaneous Determination of Dimethoxyaschantin, Dimethylliroresinol, Dimethylpinoresinol, Epimagnolin A, Fargesin and Magnolin in Rat Plasma
- Simultaneous Analysis and Quantification of Preservatives and Sweeteners in Commercial Toothpaste
- Rapid and Simple GC-MS Method for Determination of Psychotropic Phenylalkylamine Derivatives in Nails Using Micro-pulverized Extraction
- Monitoring of Formaldehyde in Cosmetic Products
- Determination of Dimecrotate in Human Plasm by LC-MS/MS Method
- Simultaneous Determination of Tar Color Additives in Cold Syrups Using a Validated HPLC Method
- Cushioning Effect of Polymers on the Matrix Tablets Containing Controlled Release Pellets
- Preparation and Characterization of Human Serum Albumin Nanoparticles Surfaced-conjugated with TNF-related Apoptosis Inducing ligand (TRAIL) as a Promising Anti-tumor Targeting Agent
- Preformulation Studies of a Newly Synthesized Molecule, QNT3-18 and QNT3-20 for Topical Formulations
- Effect of Carrier Types on Dissolution and Molecular Interaction of Solid Dispersions Containing Poorly Water-Soluble Drug
- Enhanced Topical Delivery of Processed Ginseng using Microemulsion System
- Tumor-targeted siRNA Delivery Systems Using a Syndecan Ligand
- Coumarins from the Stems of Deutzia coreana Lev.
- Cytotoxic Sterols from Sellaginella tamariscina
- Isolation of Abietic Acid from Pinus Species as a Testosterone 5α-Reductase Inhibitor
- Spirodela polyrrhiza Inhibits Nitric Oxide Production in IFN-Gamma and LPS-Stimulated Mouse Peritoneal Macrophages
- Aldose Reductase Inhibitory Activity of Methanol Extracts from Korean Folk Plants
- Preparative Isolation and Purification of Idescarpin and Its New Dimeric Compound from the Fruit of Idesia polycarpa by High-speed Counter-current Chromatography
- A Metabolite Profiling of Idesia polycarpa Fruits Extract
- New Bis-spirolabdane-type Diterpenoids from Leonurus sibiricus L.
- Chenwhangbosim-dan and Curcuma longa L. Therapeutive Effect to Alzheimer Disease
- Physcion, an Anthraquinone Isolated from Rhei Rhizoma Induces Cell Cycle Arrest and Apoptosis in MDAMB-231 Human Breast Cancer Cells
- Effect of Forsythiae Fructus and Its Main Component, Arctigenin, on Microglial Activation in LPS-stimulated BV-2 Cells
- Anti-inflammatory Activity of Xanthohumol Involves Heme Oxygenase-1 Induction via NRF2-ARE Signaling in Microglial BV2 Cells
- Anti-inflammatory Effects of Defatted Rice Bran Ethanol Extract on RAW 264.7 Cell
- Phenolic Contents and Antibacterial Activity of Selected Traditional Indonesian Plants
- The Improving Effect of Chelidonic Acid on Ulcerative Colitis
- Four New Lignans from the Root of Saururus chinensis and Their Cytotoxicity
- Herbal Medicinal Mixture Suppresses Adipogenesis and Differentiation in 3T3-L1 Adipocytes
- Discrimination of the Origins of Herbal Medicines by Gas Chromatography/Mass Spectrometry
- Chromatographic Determination of the Modification Degree of PEGylated Polyamidoamine Dendrimers
- Quantitative Analysis of Ginsenosides in Ginseng Radix palva Extracted under Various Temperature and Time
- Method Development and Validation of Letrozole in Human Plasma by LC-MS/MS
- Determination of Alendronate in Human Plasma by a Gradient HPLC/FLD with DEA-SPE Cartridge: Application of 70 mg Alendronate Sodium Tablet to a Pharmacokinetic Study in Healthy Male Korean Subjects
- Superparamagnetic Iron Oxide (SPIO) Nanoparticles-embedded Chitosan Microspheres for Magnetic Resonance-traceable Embotherapy
- Inhibition of LXRα-Dependent Steatosis and Oxidative Injury by Liquiritigenin, a Flavonoid Component in Licorice, as Mediated by Nrf2 Activation
- Estrogenic Effects of Party Pill Drugs - BZP and TFMPP
- Anti-Diabetic Activity of the Methanol Extract of L. tulipifera
- Biological Activities of Water and Ethanol Extracts from Leaves of Ligularia fischeri var. spiciformis
- Antimutagenic Study on Acanthopanax Koreanum Nakai
- Synthesis and Antifungal Evaluation of 5H-Pyrrolo [3,2-g]quinazoline-5,9(8H)-dione
- Regulatory Effects of Barley and Malt on Skin Melanogenesis in Melan-a Cells
- Cognitive-enhancing Activity of Ligustrum lucidum in Scopolamine-induced Amnesic Mice
- Determination of Atomoxetine in SD Rats' Plasma by High Performance Liquid Chromatographic Method
- Effects of Curcumin on the Bioavailability of Tamoxifen in Rats
- Patient Survival is Effected by Sp1 Expression in Different Subtypes of Gastric Adenocarcinoma
- Pattern Analysis and Monitoring of the Bioactive Components in Rhubarb
- Determination of Rhein in Human Plasma by LCMS/MS Method : Application to a Pharmacokinetic Study in Healthy Korean Volunteers
- Optimization of HS-SPME-GC/MS for the Analysis of Organophosphorous Pesticides in Blood
- Synthesis and Liquid Chromatographic Resolution of γ-Lysine Modified Peptide Nucleic Acid Analogues
- Application of UPLC/Q-Tof MS-Based Metabolomics Technique for Age Identification of Panax ginseng
- Development of Biocompatible Polymers Based on Poly(L-lactide)-Block-Poly(Ethylene Glycol) for Drug Delivery Systems
- Standardization of Analytical Method for Preservatives and Complex Drugs in Korean Pharmaceutical Codex
- Development of a Method to Identify the Origins of Herbal Medicine by GC/MS
- Enhanced Controlled Transdermal Delivery of Torasemide from the Ethylene-Vinyl Acetate Matrix
- Improved Solubility and Cellular Uptake of Paclitaxel Using Surface-modified Solid Lipid Nanoparticles with Hydrophilic Derivative Cyclodextrin
- Preparation and Evaluation of Ropivacaine Gels for Enhanced Local Anesthetic Action
- Combined Delivery of siRNA and Anticancer Drug using Mitoxantrone Lipid Derivative-based Nanoparticles
- In Vitro Assessement of Methylene Blue Hydrate as a Multiple CYP450 Inhibitor
- Doxorubicin-incoporated Nanoparticles Composed of Hyalruronic Acid/poly(DL-lactide-co-glycolide) and Its Antitumor Activity
- Pharmacogenomic Study for Individualized Warfarin Therapy
- Problems and Improvements of Herbal Preparation Benefits
- Epithelial Mesenchymal Transition in Liver Disease
- Pharmacognostical Study on a Korean Folk Medicine "DaRaeJulKi”
- Enantioselective Synthesis of (S)-4-Methyleneglutamic Acid via Tandem Conjugate Addition-Elimination Under Phase-Transfer Catalytic Conditions
- A New Explanation on the Drug Release from PLGA Nanoparticle
- Effect of Liposomal Formulation on Aminolevulinic Acid Stability in Aqueous Condition
- Effects of Anti-diabetic Herbal Medicines on the Pharmacokinetics of Metformin
- The Effects of Fluconazole Gargle on the Interactions of CNI and Hepatotoxicity in Kidney Transplant Recipients
- The Effect of Flavors on the Viscosity and Gelling Point of Aqueous Poloxamer Solution
- Dose-Dependent Pharmacokinetics of 5-Hydroxyindirubin-5-nitro-3’-monoxime in Rat
- Styrax benzoin D. (SB) on Brain Physiological Activities Monitored in Real-time
- Development and Optimization of a Novel Sustained-Release Tablet Formulation for Bupropion Hydrochloride Using Box-Behnken Design
- Choline Kinase Targeted siRNA Complex Liposome for Breast Cancer Therapy
- Preparation and Evaluation of PLGA Encapsulated PEGylated TNF-Related Apoptosis-Inducing Ligand (TRAIL) Microspheres to Prevent Protein Aggregation and Enhanced Antitumor Potency
- Effect of Surfactant on 5-ALA Uptake and PpIX Generation in Human Cholangiocarcinoma Cells
- New Anticonvulsive Pharmaceutical Treatment: Transnasal Delivery of Diazepam
- Critical Examinations on the Preparation Step of PLGA Nanoparticles
- Danshen Extract does not Alter Pharmacokinetics of Docetaxel and Clopidogrel: Negligible p-Glycoprotein and Cytochrome P4503A Mediated Herb-Drug Interaction
- Development of a Population Pharmcodynamic Model for Vincristine without Quantitation of Plasma Concentrations
- Life After Preclinical Research: Effectively Delivering Your Proposal
- Interleukin-32 is Critical in the Cancer Cell Growth Inhibitory Effect of NK Cells via Activation of Death Receptor 3
- Anti-Colitic Effect of Compound Rh1, a Metabolite of Ginsenoside Re, in Mice
- Fieldwork and Related Studies on Cinnamon
- Lentivirus-Mediated Nrf2 Knockdown and its Implication for Docetaxel Sensitivity in Breast Cancer Cells
- Antibacterial and Antioxidant Activity of Nepalese Wild Herbs
- Diosgenin Induces Apoptosis in HepG2 Cell through the Mitochondria/Caspase Pathway
- Gastrodia elata Attenuates Colonic Damage in Mice with Experimental Colitis
- The Role of Prolyl Isomerase Pin1 on the Expression of HER-2 Oncogene via Pin1-MEK1-AP-2 Alpha Signaling in Breast Cancer
- Chemical Constituents of Polygala tenuifolia and Their Inhibitory Activity on Lipopolysaccharide-induced Nitric Oxide Production in BV2 Microglia
- Determination of Tolperisone in Human Plasma by Liquid Chromatography-Electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and Its Application to a Pharmacokinetic Study
- Enantioselective Iridium-Catalyzed Carbonyl Allylation and Crotylation from the Alcohol or Aldehyde Oxidation Level and Its Application to the Total Synthesis of (+)-Roxaticin
- A Naphthoquinone Derivative Can Induce Anemia through Phosphatidylserine Exposure Mediated Erythrophagocytosis
- Cholesterol-derived Novel Anti-apoptotic Agents on the Structural Basis of Ginsenoside Rk1
- Harnessing Reactive Intermediates-Application to Heterocycle Synthesis
- Synthesis of Coumarin Derivatives as Acetylcholinesterase Inhibitors
- A Synthesis of Phenanthridone Alkaloid Analogues through Heck Coupling
- Preparation and Evaluation of Hyaluronic Acid Microsphere for Controlled Drug Delivery
- Estrogenic Activity and Anti-proliferative Effect of Soy Products
- Synergistic Anti-cancer Effect on Cholangiocarcinoma Cells by Co-treatment with Gemcitabine and Cisplatin and Drug Loaded Stent Coating
- Fc-binding Peptide-based Immunoliposome as Universal Cargo of Antibodies
- Patient Oriented Care Services in Community Pharmacy: A Theory Based Approach
- A New pH-sensitive Polymer Based on Imidazole Modified Polypeptide Block Copolymers for Acidic Targeting Nanovehicles
- S1P Circulation in Plasma
- Synthesis and Evaluation of Compounds which Induce Readthrough of Premature Termination Codons
- Dibenzylbutyrolactone Lignans from Forsythia koreana Fruits Attenuate LPS-Induced iNOS and COX-2 Expressions through Activation of NF-κB and Mitogen-Activated Protein Kinase in RAW264.7 Cells
- The Role of Hypoxia and LXR Activation in the Formation of Triglyceride-Loaded Form Cells
- Anti-oxidative and Nitric Oxide Production Inhibitory Effect of Gallotannins from the Barks of Acer ginnala Maxim
- Integrated Platform for Studying Biomarkers, Cytotoxicity and Systems Medicine
- 1,2-Diacetylbenzene Impairs Neural Progenitor Cells and Hippocampal Neurogenesis
- A Potent and Noncytotoxic Inhibitor of Melanin Production Identified through Parallel Solution-Phase Synthesis
- Formulation of Stimuli-Sensitive Drug Delivery System for Mucosal Delivery of Amphotericin B
- Liposome-mediated Photosensitizer Delivery for Squamous Cell Carcinoma Treatment
- Docetaxel-Loaded Polymeric Nanoparticles Potentiate Radiotherapeutic Efficacy
- The Effect of Extracts Including Quercetin-3-β-Dglucuronopyranoside on the Motility of Feline Esophageal and Ileal Smooth Muscle
- Transforming Growth Ractor-b1 Downregulates Caveolin-1 Expression and Increases S1P Level in HUVECs via Sphingosine Kinase Activation
- 15-Deoxy-12,14-prostaglandin J2 Induces Elk-1-mediated Expression of 15-Hydroxyprostaglandin Dehydrogenase in Human Breast Cancer Cells
- Aroclor 1254 Disturbs Estrogen Receptor-mediated Neuroprotection Against Beta-amyloid Toxicity in Cholinergic SN56 Cells
- Active Compounds Isolated from Clematis chinensis (Ranuculaceae) Inhibit IL-4 Signaling Transduction by Inducing SOCS-1 Gene Expression
- Metabolomic Profiling of Cisplatin-Induced Nephrotoxicity in Human Kidney HK-2 Cells
- Anti-Obese Effect of Atractylodis Rhizoma Water Extract in High Fat Diet Fed ICR Mice
- The Proliposomes Containing Advanced Adipose Derived Stem Cells Protein Extract Inhibit Development of Atopic Dermatitis in Nc/Nga Mice
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