학술논문
Synthesis and Biological Evaluation of New Arylpiperazine-Containing Pyrrole 3-Carboxamide Dericatives
이용수 0
- 영문명
- 발행기관
- 대한약학회
- 저자명
- PARK Eun-Jung KANG Suk Youn SEO Hee Jeong KIM Min Ju KIM Hyun Jung JUNG Myung Eun PARK Woo-Kyu JEONG Daeyoung PAE Ae Nim KIM Jeongmin LEE Jinhwa
- 간행물 정보
- 『춘계총회 및 학술대회』(2010년), 185~185쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2010.04.16
무료
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
영문 초록
목차
키워드
해당간행물 수록 논문
- Comparative Proteome Analysis Reveals Flotillin-1 as an H-Ras-Interacting Lipid Raft Protein Critical for Breast Epithelial Cell Invasion
- Physicochemical Characterizations and Cytotoxicity of Four Extracts from Alnus japonica with Various Extraction Solvents
- Current Trends of PBL in the United States
- Relaxant Effect and Mechanism of Eupatilin on Carbachol Induced Contraction of Rat Ileum and Colon
- Asymmetric syntheses of (+)-Sertraline and (+)-Indatraline
- A Case Study of Curriculum Change in U.S. Pharmacy Education
- Ajoene, a Stable Garlic Byproduct, Inhibits High Fat Diet-Induced Hepatic Steatosis and Oxidative Injury through AMPK Activation
- MHY-A Suppresses Melanogenesis through Tyrosinase Inhibition
- Peroxyl Radical Scavenging Capacity of Extracts and Isolated Components from Selected Medicinal Plants
- Defective Antigen-presenting Capacity of Myeloidderived Suppressor Cells from Late Stage Tumor-bearing Mice Can Be Recovered by NKT Cell Help and ATRA Treatment
- Streptococcus pneumoniae ClpP Induces Apoptotic Cell Death in Neuroblastoma
- The Anti-oxidative Stress Effect of Sargassum Muticum Extracts in the HaCaT Cell
- Regulation of Liver X Receptor Alpha-Dependent Hepatic Lipogenesis through Adenosine Monophosphate-Activated Protein Kinase Pathway on Orotic Acid-induced Liver Steatosis
- Dietary Ferulate Modulates Renal FOXO3a Activity via the PI3K/Akt Pathway during the Aging Process
- Compound 402 Potentiates the Vaccine Adjuvant Effect of Flagellin, a TLR5 Agonist through PKC-Dependent Signaling Pathways
- 4-O-Methylhonokiol Attenuated Memory Impairment via Reduction of Aβ Accumulation in a Mouse Model of Alzheimer’s Disease
- Effect of Saponins from the Root of Platycodon Grandiflorum on Acrolein-induced Mucin Expression in Lung Epithelial Cells
- Immunomodulatory Effect of Sc-SGF on Macrophage Functions
- Toll-like Receptor 4-Dependent Maturation of Dendritic Cells by Polysaccharide Isolated from Cordyceps militaris
- Degeneration of t-Tubules in Rat Ventricle Cells by Culturing
- Saving Mice but Not Patients: Challenges for Sepsis Models in Treatment Development
- Inhibitory Effect of Sanguisorba officinalis Extract on Lipopolysaccharide-induced Pro-inflammatory Events in Macrophages
- Microbial Enzymes: Purification, Biochemical Characterization and Its Application for Biodiesel Production
- Trichostatin A Regulates the Protein Stability of ERα through Acetylation-dependent Stabilization of p300
- A Rapid and Sensitive Determination of Adefovir In Human Plasma by Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic Study
- Anti-mutagenic Effects of Acanthopanax koreanum Nakai using Ames Bacterial Reverse Mutation Assay
- Sesquiterpenoids from Laurus nobilis L. Leaves
- Synthesis and Anti-Hepatitis C Virus (HCV) Activity of 3'-C-Substituted-methyl Pyrimidine and Purine Nucleosides
- Bioequivalence Evaluation of Morniflumate 350 mg Tablets in Healthy Male Korean Volunteers
- Cytotoxic and Anti-inflammatory Effects of Six Species of Lactic Acid Bacteria
- Choline Kinase Targeted siRNA for Breast Cancer
- Sesquiterpenes from Lindera strychnifolia Roots Inhibit HSC-T6 Hepatic Stellate Cells
- Anti-inflammatory Compound from Carpesium macrocephalum Inhibits the Activation of p38, JNK through Down Regulation of NF-κB
- Synthesis of Amino Lipid-based PEG Conjugate and Preparation of Cationic Liposomes for siRNA Delivery
- Are we Prepared for PBL?
- Mechanism of On-Contraction Induced by Electrical Field Stimulation in Feline Esophageal Smooth Muscle
- Enviromental Influences on Gentamicin Pharmacokinetics by Using Population Pharmacokinetic Methods
- Stereoselective Synthesis of Pachastrissamine and its Epimers
- Flavonoids from the Stems of Stewartia pseudocamellia Maxim
- Celecoxib Pharmacokinetics in Relation to CYP2C9 Genotype
- Inhibitory Constituents of Sigesbeckia pubescens on Lipopolysaccharide-induced Nitric Oxide Production in BV2 Microclia
- Design of Silymarin-loaded Solid Dispersion System with Enhanced Solubility Using PVP K30, Tween 80 and Water
- Quantitative Proteomic Analysis of Colorectal Cancer Tissues for Biomarker Discovery
- In-line NIR Quantification of Film Thickness on Pharmaceutical Pellets during a Fluid-bed Coating Process
- A Novel Signaling Pathway for Enhancement of Neutrophil Bactericidal Activity
- Effect of TH1001 in the Tinnitus Animal Model
- The Extract of Artemisia capilaris Ameliorates Memory Impairments Induced by Scopolamine or Transient Forebrain Ischemia in Mice
- Anti-inflammatory Activity of Bark of Dioscorea batatas DECNE through the Inhibition of iNOS and COX-2 Expressions in RAW264.7 Cells via NF-κB and ERK1/2 Inactivation
- Anti-Diabetic Effect of Triticum aestivum Aqueous Extracts in Insulin Dependent Diabetic Mice Model
- Mono and Bicyclic Aminopyridinols as Antioxidants
- Purification and Crystallization of Prephenate Dehydratase
- Evaluation of Anti-inflammatory Activity of Andrographolide in Lipopolysaccharide-stimulated Macrophage Cells
- Anti-platelet Activity of Phellinus baumii Methanol Extract: Involvement of Inside-out Signaling but not Outside-in Signaling
- Mechanism Based Development of Therapeutic Agents for Treatment of Alzheimer’s Disease
- (-)-Epigallocatethin-3-O-gallate (EGCG) Counteracts Caffeine-induced Pharmacological Effects
- Risk Assessment Study of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
- Synergistic Effects of Valsartan Combined With Cilnidipine on Hypertension and Cardiovascular Disease
- Evaluation of Some Ginger Plant Extracts on Melanin Formation Inhibition in B16 Melanoma Cells
- Bioactive Constituents from the Capsosiphon fulvescens
- Heterocycle-linked Thioureas for the Inhibition of NO Production in LPS Activated Macrophages
- Development of Analytical Method and Monitoring of UV Filters in Cosmetics
- Synthesis and Evaluation of Branched Chain-Containing α-GalCer Derivatives
- Label-free, Real-Time Cell Analyzer - xCELLigence Innovative Technology for Drug Discovery and Cell-Based Assays
- Synthesis and Anticancer Activity of New Allylselenopyridazines
- Development of Her2 Inhibitor for Gastric Cancer
- A New Steroidal Saponin Isolated from Asterias amurensis
- Enantioselective Carbonyl Allylation from the Alcohol or Aldehyde Oxidation Level via Transfer Hydrogenative Coupling of Allyl Acetate
- Pharmacokinetics of Magnolin and Epimagnolin A after Oral Administration of Standardized Extract of Magnolia fargesii, NDC-052 in Rats
- Bioequivalence of Bambucol Tablet to Bambec Tablet (Bambuterol Hydrochloride 10 mg)
- Novel Amino Alcohol Derivatives of Chromone for their IL-5 Inhibitory Activity
- Protein Tyrosine Phosphatase 1B Inhibitory Activity of Chalcone Derivatives
- The Role of Kupffer Cells on Hepactic Cytochrome P450 Enzymes during Polymicrobial Sepsis in Rats
- Platycodin D, Triterpenoid Saponin from Platycodon Grandiflorum Induces Cell Cycle Arrest and Apoptosis in Human Cancer Cell Lines.
- Function of ARD1 in Zebrafish Development
- Transplantation of Skeletal Myoblast with Injectable Polymer Scaffolds Improves Cardiac Function in Myocardial Infraction Rat Model
- Identification and Quantification of Proteins Related Insulin Resistance in PUGNAc Treated 3T3-L1 Adipocytes using ATP-affinity Chromatography
- Cloning, Expression and Purification of α-L-Arabinofuranosidase from Bifidobacterium longum H-1
- Guideline for the Evaluation of Analytical Method for Bioequivalence Study
- Anti-Allergic Effects of Sinomenine by Inhibition of Prostaglandin D2 and Leukotriene C4 in Mouse Bone Marrow-Derived Mast Cells
- Endogenous Concentrations of Gamma-Hydroxybutyric Acid (GHB) and Its Stability in Korean Urine Samples
- Pharmacokinetics of Mirodenafil and Its Two Metabolites, SK3541 and SK3544, in Spontaneously or DOCASalt-Induced Hypertensive Rats
- Responsive Neurovascular Unit: The Role of AKAP12 in Blood-neural Barrier Functioning
- Role of Drug Metabolism and Pharmacokinetics (DMPK) in Drug Discovery and Development
- Small Molecule Drug Discovery for the Treatment of Metabolic Disorders
- Review of the Evaluation Project on Appropriate Prescribing from Foreign Countries' Experience
- Effects of Chinese Ferns on Antioxidation and Inhibition of Matrix Metalloproteinase in Human Skin Fibroblasts
- Development of a Simple and Sensitive HPLC-MS/MS Method for the Determination of Atomoxetine in Human Plasma
- Design and Synthesis of SATE Derivatives of 2’- or 4’-Modified Carbocyclic Nucleoside Phosphonates
- HS-1793, a Resveratrol Analogue, Induces Apoptotic Cell Death, Cell Cycle Arrest and Affected Hypoxia Induced Expression of HIF-1 in Human Breast Cancer Cells
- RORα Regulates the Expression and the Transcriptional Function of LXRα
- Investigation of Intrinsic Dissolution Behavior of Fluconazole Polymorphs Prepared by the SAS Process
- Determination of Omeprazole in Human Plasma Using a LC-MS/MS Analytical Method and Its Application to a Pharmacokinetic Study
- Bioactivities of Extracts from Liriodendron tulipifera
- Regulatory Effects of Src-dependent Heme Oxyganase-1 Expression by Hydroquinone in Macrophage-like RAW264.7 Cells
- The Improve Effects of Saengmaeksan on Ulcerative Colitis
- Inhibition of DNA Topoisomerases I and II and Cytotoxicity of Ulmus davidiana var. japonica
- A Novel Peptide Antibiotic from Bacillus amyloliquefacines BA6
- In Vitro Cytotoxicity of Cytokine-Induced Killer Cells Mainly Depends on CD3+NK1.1+ Subset
- Quality Control of Modified Boyanghwano-Tang through Simultaneous Determination of Major Constituents by HPLC
- Constituents with DNA Topoisomerase I and II Inhibitory Activity and Cytotoxicities from Euonymus alatus
- The Biological Activities of Brown Rice and Rice Bran
- A Research of Atopic Dermatitis Animal Model
- Prediction of Clinical Outcome of Human Cancers Using Gene Expression Profile
- Procoagulant and Prothrombotic Activation of Human Erythrocytes by Phosphatidic Acid
- Anti-inflammatory Potentials of Coptis chinensis for the Prevention and/or Treatment of Atopic Dermatitis
- Mitochondrial Dysfunction in the DJ-1 K.O. and PINK1 K.O., Mutant Dopaminergic Neuronal Cells of Familial Parkinson’s Disease
- Role of Dieckol in TPA-Induced MMP-9 Activation in Human Hepatoma SK-Hep1 Cells
- Simultaneous Determination of Celecoxib and its Carboxylic Metabolite in Human Plasma by LC-MS/MS
- Synergistic Effects of Valsartan Combined with Amlodipine in SHRs and Mice
- Effect of Galla rhois on the Aroclor 1254-Induced Hyperactivity and Learning Impairments
- Molecular Cloning and Chacterization of Human Anoctamin7
- Formulation and Dissolution Rate Evaluation of Matrix Based on Sustained-Release Tablets Containing Sarpogelate-HCl
- Effect of Rosiglitazone-loaded Cationic Lipid Emulsion on the Physicochemical Properties and Stability of Lipoplexes Encoding Adiponectin
- Involvement of GABAA Receptor in Attenuation of Methamphetamine-Induced Hyperlocomotion by MDL72222 in Mice
- Potent Protective Effect of Cryptotanshinone against 7,12-Dimethylbenz[a]anthracene-Inducible Genotoxicity in Human Breast Cancer Cells
- Enhanced Expression of Mitochondrial Superoxide Dismutase Leads to Prolonged In Vivo Cell Cycle Progression and a Concomitant Up-Regulation of Mitochondrial Thioredoxin
- Emodin as 5α-Reductase Inhibitory Components from Polygonum multiflorum (Polygoni Multiflori Radix)
- Development of Second Generation Interferon-β1a for the Treatment of Multiple Sclerosis
- Apoptosis-Inducing Activity of Compounds from the Fruit Bodies of Ganoderma lucidum
- Antioxidant Effect of Some Medicinal Plants from East Kalimantan, Indonesia
- Anti-allergic Effects of Meoruh Wine on Mast Cellmediated Allergic Model
- HPLC Condition for Determination of Five Active Isoflavones in Rat Plasma Using Liquid Liquid Extraction for SEM, Dissolution Study, Solubility Study, Measurement of Particle Size and Zeta Potential
- Simultaneous Determination of Bioactive Components in Leonuri Herba for Quality Control by HPLCDAD and LC-ESI-MS/MS
- Persistence of the Ability of Methamphetamine Preexposure to Induce Conditioned Place Preference in SHR and Wistar Rats
- Modulation of IL-12 and IFN-γ Secretions by Lignans from Acanthopanax koreanum Nakai
- Natural Occurring Phenylpropanoids Inhibit LPSinduced NF-κB Activation via the inhibition of IκB and IKK Phosphorylation
- A Sensitive Validated LC-MS/MS Method for the Determination of Udenafil in Rat Plasma for the Pharmacokinetic Studies
- Prevention of Hepatic Steatosis by Carbenoxolone through SREBP-1c Pathway and Anti-apoptotic Action
- Induction Cell Cycle Arrest by Methanolic Extract of Mahonia bealei in HT-29 Cells
- Possible Neuroprotective Mechanisms of Quercetin 3-Methyl Ether Isolated from Opuntia ficus-indica var. saboten
- Anti-obesity Effect of folium perillae Extracts Involves the PPAR-γ Signal Pathways in 3T3-L1 Cells
- Synthesis and Pharmacological Evaluation of Celecoxib Derivatives
- Ginsenoside Rg2 suppresses glucose production via AMPK activation in HepG2 cells
- Complement Component 3 Mediated Brain Injury is Upregulated by Oxidative Stress after Focal Cerebral Ischemia.
- Resveratrol Modulates RTX Toxin-Induced Cytotoxicity through Interference in Adhesion and Toxin Production
- Folate Receptor Targeted, Superparamagnetic Iron Oxide Nanoparticles for Chemotherapy and Magnetic Imaging of Liver Cancer
- Synthesis, Topoisomerase I and II Inhibitory Activities and Cytotoxicity oF Hydroxylated Terpyridine Bioisostress
- New Phytochemicals from Commercially Processed Dry Ginger (Zingiber officinale)
- Hepatoprotective Activity of Taraxacum mongolicum H. Complex (TMC) against Carbon Tetrachloride (CCl4)-induced Hepatotoxicity
- Adult Neurogenesis Impairment in Stress-Related Psychiatric Disorders
- Ultra High Definition LC-MS portfolio: Introducing High-end LC-MS Technologies for Pharmaceutical Studies
- Ginseng Extract Increases Spontaneous Sleeping via GABAergic Systems
- Ameliorating Effects of the Ethanol Extracts from GP-EX on Chronic Electric Footshock Stress
- Determination of Impurities in Pharmaceutical Products by Online Pre-treatment System Combined with LCMS-IT-TOF mass spectrometer
- Effects of Cordycepin on the Alternations of Sleep Architecture and EEG Power Spectra in Rats
- Hepatitis B virus X Represses CCAAT/Enhancer Binding Protein β-Dependent Phase II Detoxifying Enzymes Expression
- Synergistic Increase of BDNF Release from Rat Primary Cortical Neuron by Combination of Several Medicinal Plant-derived Compounds
- Antioxidant and Free Radical Scavenging Activity of Gynostemma pentaphyllum
- Antitumor Activity of Myriocin, a Sphingolipid Biosynthesis Inhibitor, and Its Mechanism in Melanoma Mice
- Neuroprotective Effects of Some Compounds of Morus alba L. against Oxygen-Glucose Deprivation(OGD) Induced Oxidative Cell Death on Neuronal Cells
- The Anticolitic Effect of Cyanidin-3β-D-glycoside Isolated from Black Rice
- The Pharmacokinetic Interactions of Cimetidine and Pramipexole in Relation to OCT2
- Synthesis, Characterization and Application of Exendin-4 by Approaches of Functionalized Bioconjugations
- Structure Activity Relationship of 5,8-Dimethoxy-1,4-naphthoquinone Derivatives on PDGF Inhibitory Activity
- Macrolactins, Antimicrobial Macrolides from a
- A Concise Total Synthesis of (+)-Tetrabenazine and (+)-α-Dihydrotetrabenazine
- Synthesis and Anti-tumor Effects of CB-dimers without Aldedyde Group
- Detection of Benzodiazepines and Hypnotics Used to Drug-Facilitated Crimes in Biological Specimens by LC-MS/MS
- Oxygen Radical Absorbance Capacities of EtOAc Layers from Natural Plants, Persicaria perfoliata and Sorbaria sorbifolia var. stellipila MAX
- An Improved Procedure for Preparation of 4’-Hydroxydichlofenac
- Inhibition of HIV-1 Protease and Cytopathic Effects by Flavans and Lignans from Stem Barks of SNUPH-0052
- On the Relation of Paeonia lactiflora Pallas Complex (PLC) to Nifedipine-induced Gingival Hyperplasia and Impaired Submandibular Glands Function in Rats In Vivo
- Cyperi Rhizoma has Protective Effects Against Dopaminergic Neuronal Damage Induced by 6-Hydroxydopamine
- Application of NIR In-line Monitoring for Manufacture of Acetaminophen FormII in Solution
- Murrayafoline A and their Analogues; Synthesis and Evaluation as Inhibitor of the Wnt Signaling
- Protective Effect of [6]-Gingerol against β-Amyloidinduced Pro-inflammatory Damages and Cell Death
- Neuroprotective Flavonoids of Rhus verniciflua Barks on Glutamate-Induced Oxidative Injury in HT22 Hippocampal Cells
- Formulation and Evaluation of Captopril Gastric Retension Tablets Using Floating DDS System
- New Cystine Knot Peptides from a Marine Sponge Asteropus sp.
- Mechanism Studies of Calpain Inhibitors Discovered through High-throughput Screening
- Detection of 4-Methylaminoantipyrine in Equine Plasma and Urine after Administration of Dipyrone by GC/MS and LC/MS/MS
- Development of New Anticancer Drug-like Molecule for Her2-Positive Human Breast Cancer
- NIR-based In-line Monitoring of The Crystallization Process of Acetylsalicylic Acid
- The Comparative Study of Anti-allergic Inflammatory Effects by Fermented Red Ginseng and Red Ginseng
- Determination of Anti-diabetic Drugs by Liquid Chromatography-charged Aerosol Detection and Comparison of Ultraviolet Detection and Evaporative Light Scattering Detection
- Characterization of Human Liver CYP and UDPglucuronosyltransferase Enzymes Involved in Jaceosidin Metabolism
- Enantiomer Resolution of Amino Acid Esters as 9-Anthraldimine Derivatives on Polysaccharide-derived Chiral Stationary Phases
- Essential Oil from Thujopis dolobrata Suppresses Development of Atopic Dermatitis-like Skin Lesion in NC/Nga mice
- Effects of 70% EtOH Extract of Rumex crispus L. on the Induction of Apoptosis and Inhibition of Lipid Accumulation in 3T3-L1 Cell
- Synthesis of Novel C-glucosides with 1,3,4-Thiadiazole Ring as Sodium-dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus
- Antioxidant constituents isolated from leaves and twigs of Juglans sinensis
- Population PK Modeling for Analysis of Relationship between Glucose-lowering Effects and Plasma Concentration of Metformin in Volunteers
- Xanthone Constituents of the Fruits of Garcinia mangostana with Anticomplement Activity
- The Ethanolic Extracts of Torilis fructus Ameliorates Learning and Memory Impairments Induced by Scopolamine in Mice
- Antifungal Activity and Phytochemical Study of Selected Medicinal Plants in East Kalimantan
- Herceptin-conjugated Immunoliposomes Encapsulating Gemcitabine for Breast Cancer
- Fabrication and in vivo, in vitro Evaluation of Salmon Calcitonin-Sodium Tripolyphosphate Ionic Complex System
- Preparation of Double Layer that has Forms of Following Process Method and Controlled Release of Dexibuprofen
- Review of Drug Classification Systems and Use of WHO ATC
- Protective Effects of MH022 on Rat Primary Neuronal Cultures in Aβ25-35-induced Alzheimer’s Disease Models
- The Effect of Prilocaine·HCl on Rotational Mobility of n-(9-Anthroyloxy)stearic acid in Neuronal Membranes
- The Improvement of Bioavailability of Insoluble Raloxifene HCl by using SMEDDS
- Discovery of Methyl Aryloxy Gallates as a Potential Scaffold for Regulation of Vascular Smooth Muscle Cell Proliferation
- Monitoring of Hazardous Heavy Metals in Watercolor Paints
- Hepatoprotective Effect of Luteolin on Fulminant Hepatic Failure by D-Galactosamine/Lipopolysaccharide
- Exploration of Oxidative Stress-Induced Inflammatory Mechanism by Angiotensin II in Aged Rat Kidney
- Anti-inflammatory Effects of Novel Kojic Acid Derivative, KNU-286, in LPS(lipopolysaccharide)-engaged Macrophages
- Regulation of Saponins Derived from Roots of Platycodon Grandiflorum on Osteoblast Differentiation Mediated through Runx2 Activation
- Baicalein Inhibits IR-induced Proinflammatory Responses through Regulation of NF-kB and FOXO Signaling Pathways
- Effects of Novel α-Tocopherol Analogs on TGFβ1-Induced Epithelial-Mesenchymal Transition in Rat Kidney Epithelial Cells
- Change of Human Salivary α-Amylase Activity Free Radical Scavenging Activity and Cortisol Level after Psychological Stress during Examination Task
- Metabolomic Study for Hepatotoxicity Evaluation Using In Vitro Systems
- The Effect of Epstein-Barr Virus Infection on Chemoresistancy of 5-fluorouracil in Gastric Carcinoma Cells
- Novel Blockers for Retinal Vascular Leakage
- Capsaicin Inhibits Migration of Fibrosarcoma Cells: Possible Mediation by Decreased ERK and p38 MAPK/AP-1 Signaling
- Anticancer Activity of All-trans-Retinoic Acid-Histone Deacetylase Inhibitor Conjugate Delivered by Liposomes
- Antioxidant Flavonoids from the Twigs of Stewartia koreana
- Asymmetric Synthesis of (-)-Codonopsinine
- Structural and Molecular Modeling Studies of Herbal Compound Farnesiferol C Targeting Src Tyrosine Kinase and Focal Adhesion Kinase
- Liquid Chromatography-tandem MS Quantification of FTY720-phosphate Released from HUVEC
- Safety Evaluation of Gene Therapy Products Using Electroporation
- 2-Thienyl-4-furyl-6-aryl Pyridine Derivatives: Synthesis, topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure Activity Relationship Study
- H+ Entry Affect Cell Responses Under Low pH Condition in Cultured Feline Esophageal Epithelial Cells
- Simultaneous Determination of Aripiprazole in Human Plasma by Liquid Chromatography/tandem Mass Spectrometry with Electrospray Ionization
- Study of Endogenous Metabolites for Safety Evaluation of Anti-Inflammatory Drugs
- Carbon Monoxide Inhibits Release of Late Phase of Pro-Inflammatory Cytokine, HGMGB1, in LPS or CLP-Induced Sepsis Rats
- Effect of Resveratrol on Doxorubicin-mediated Cell Proliferation, Invasion, and Migration in Human Breast Cancer Cells
- IL-32β Prevents Colon and Prostate Cancer Cell Growth by Inhibition of NF-κB and STAT3 Signals
- Neuroprotective Effects of Some Plant Extracts Against Oxygen-Glucose Deprivation-Induced Oxidative Cell Death on Neuronal Cell
- Anti-allergic Inflammatory Properties of Clinopodium gracile Matsum var. multicaule
- Design and Synthesis of Novel Prodrugs of Arylsulfonylimidazolidinone (JSH2282) for Selective Activation by Tumor-Associated Plasmin
- Effects of Decursin and Decursinol angelate on Sperm Count in male Rats
- Synthesis and Biological Evaluation of New Arylpiperazine-Containing Pyrrole 3-Carboxamide Dericatives
- Synthesis Of Calpain Inhibitory Chromone 2-Carboxamides Derivatives
- Inhibition of Mitochondrial Glycerol-3-Phosphate Acyltransferase by Flavonol Glycosides Isolated from Leaves of Aceriphyllum rossii
- Total Synthesis of (2R, 5R)-Dihydroxymethyl-(3R, 4R)-Dihydroxypyrrolidine (DMDP) using stereoselective CSI-mediated Amination
- Iterative Two-directional Enantioselective Carbonyl Allylation and Crotylation: Total Synthesis of (+)-roxaticin
- Determination of Motelukast Sodium in Human Plasma by Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic Study
- Direct Enantiomer Resolution and Optical Purity Determination of Thyroxine Enantiomers in Pharmaceutical Formulations
- Hepatic and Ovarian Expression of Cytochrome P450 During the Estrus Cycle in the Rat
- Neuroprotective Effect of Morus alba Extracts in N18-RE-105 Cells
- Preparation of Docetaxel Nanoparticles Using Biocompatible and Biodegradable Polymer, PLGA.
- Development of a New Therapeutic Drug for Angiogenesis-associated Diseases
- Cytotoprotive Activity of Isoquercetin Isolated from Kalopanax pictus Leaf
- Attenuation of Methamphetamine-Induced Nigrostriatal Dopaminergic Toxicity by Pharmacological and Genetic Inhibition of Protein Kinase Cδ
- Effects of AT2-Receptor Antagonist on Catecholamine Release in the Isolated Perfused Rat Adrenal Medulla
- Monitoring of Cadmium, Chromium in Color Cosmetics
- Inflammatory Response by SWCNT in CCR5 Knockout Mice
- Development of New Reporter Gene Assay System from Carassius auratus to Detect Dioxin-like Activity
- Effect of Saponins from the Root of Platycodon Grandiflorum against Non-Alcoholic Fatty Liver Disease of Rats Fed High-Fat Diet
- Mechanism of Fatty Liver Induced by Chronic Ethanol Administration-Involvement of Nuclear Receptor PXR and Its Target Gene Cyp3a11
- Biological Monitoring of Phenols in Human Breast Milk
- Newly Synthesized Resveratrol Analogs:Potent Sirt 1 Activators against UVA-induced Inflammation
- Minimum Structural Requirements for Herbicidal Evaluation of 5-(R1)-6-(R2)-N-(R3-phenyl)-pyrazine-2-carboxamide Analogues as New Class Potent Herbicide
- Effects of Cherry Tomato on Prostate Cancer Prevention
- Biochemical Properties of Hemagglutinin Isolated from Drosophila melanogaster.
- Characterization of Protein L-isoaspartyl Methyltransferase as Histone Methyltransferase
- CXCL2 Induced by Receptor Activator of NFkB Ligand Enhances Osteoclastogenesis
- Antioxidation and Antiwrinkling of Fermentated Cosmetic Ingredients
- The G12 Family Proteins Upregulate Matrix Metalloproteinase-2 via p53 Leading to Human Breast Cell Invasion
- Docosahexaenoic Acid Protects against UV-induced Oxidative Stress through Upregulation of Heme Oxygenase-1 and NAD(P)H: Quinone Oxidoreductase in Mouse Epidermal Cells
- The Role of Interaction between Hepatitis B Virus X Protein and PARP1 on DNA Repair
- Modulation of Transcriptional Activity of Runx through Dimerization
- Profiling of Proteins Related to PUGNAc-induced Insulin Resistance in C2C12 Myotubes using Lectin Affinity Chromatography and LC MS/MS-based Proteomics Technology
- Dual Phosphorylation Snail by GSK3beta and CK1epsilon
- Sulforaphane Inhibits Activation of Toll-like Receptor 4 in a Thiol-dependent Manner
- Neuroprotective Effects of Ethyl Pyruvate Derivatives by Transition Metal Chelation
- Synthesis of D-2’-Methylneplanocin A as Potential Anti-HCV Agent
- A New Phenolic Glycoside from Bridelia cambodiana
- Anti-inflammatory and Anti-nociceptive Effects by the Roots of Aconitum ciliare in Rats
- A New Daphnane Type Diterpene Ester from Daphne genkwa
- Electrotransport of Calcitonin Through Skin
- Study on the Establishment of Dissolution Specifications for Octylonium Bromide Tablets and Pinaverium Bromide Tablets in Korea Pharmaceutical Codex
- Brain Permeability and Pharmacokinetic Analysis of Ginsenoside Rh1
- Effect of Phenol Red in Culture Media on Function and Expression of P-glycoprotein in LLC-PK1, MDCKII and LS174T Cell
- Preparation and Characterization of rhEGF (recombinant human epidermal growth factor)-loaded Solid Lipid Nanoparticels(SLNs) for Topical Delivery
- Oxidative Stress-Adaptive System NRF2: A Novel Potential Target for Controlling Cancer Cell Growth
- Analysis of Physicochemical Composition and in vitro Anti-oxidant Properties of Barnyard Millet (Echinochloa crus-galli, utilis, esculenta) Cultivars
- Effect of Stable Inhibition of NRF2 on Doxorubicin Sensitivity of Human Ovarian Carcinoma OV90 Cells
- The Regulation of TGF-β Negative Regulator by IN-1130, an ALK5 Inhibitor
- c-Myc Induces Epithelial Mesenchymal Transition in Mammary Epithelial Cells
- Radiosensitizing Effects of Xanthohumol on Human Cancer Cells
- Inhibitory Effect of Sulforaphane on Differentiation of 3T3-L1 Cells
- Atomoxetine Pharmacokinetics in Relation to CYP2D6*10 Allele
- The Changes of Phospholipase A2 and Phospholipase C Activity Exposed to Extremely Low Frequency-Electromagnetic Field in Leukocytes
- Melanogenesis Inhibition of Thiopyrimidine Derivative QNT4-32 by Acceleration of Tyrosinase Degradation
- The Regulatory Effect of Bay K8644 on RANKLinduced Osteoclast Formation
- Comparative Analysis of Screening Results from Various ELISA Formats Used for Detection of Antierythropoietin Antibodies
- Synthesis and Biological Properties of Benzo-Annulated Rutaecarpines
- Phytochemical Constituents from the Whole Plant of Potentilla kleiniana
- Comparative Analysis of the Quantitative Risk-Benefit Evaluation for Drugs
- Characterization of In Vitro and In Vivo Pharmacokinetics of PDE-310, a Novel PDE IV Inhibitor
- Flavonoids from the Aerial Parts of Persicaria filiforme Nakai
- A Novel Solid Self-microemulsifying Drug Delivery System (SMEDDS) Prepared by Spray-drying to Enhance the Solubility of Tacrolimus
- Biological Activities of Carotenoids and Carotenoid Extract from Carrots and Transgenic Carrots Overproducing Various Carotenoids
- Effect of Forsythiae Fructus and Its Main Component, Arctigenin, on Microglial Activation in LPS-stimulated BV-2 Cells
- Transplantation of Skeletal Myoblast Containing Genes Related to Differentiation and Angiogenesis Improves Cardiac Function in Ischemic Rat Heart Failure
- Evaluation of Anti-pigmentary Effect of Synthetic Sulfonylamino Chalcone
- An Efficient Total Synthesis of Valienamine via CSImediated Stereoselective Amination
- The Preliminary Study of Docetaxel Formulation for Intravenous Delivery with Docetaxel Prodrug
- Inhibitory Effect of Embelin, a Specific XIAP Inhibitor on the Growth of Human Prostate Cancer Cells
- Kalopanaxsaponins Isolated from Kalopanax pictus Ameliorate Memory Deficits in Mice.
- Inhibitory Effects of Captopril on Catecholamine Secretion from the Rat Adrenal Gland
- Rheology Evaluation of Natural Products for Patients with Dermatitis
- Homoisoflavonoid Derivatives from the Roots of Ophiopogon japonicus and Their In vitro Anti-inflammation Activity
- Physical Stability of Protein Drugs and Their Thermodynamic Evaluation
- Preparative Isolation of Idescarpin from the Fruit of Idesia polycarpa by High-Speed Countercurrent Chromatography
- Preparation and Evaluation of Gastic Mucoadhesive Formulations for the Improvement of Gastroprotective Effect
- Inhibitory Activity of the Root Extract from Glycyrrhiza uralensis on acyl-CoA: Cholesterol Acyltransferase (ACAT)
- Invetigation of Natural Products from Marine Resources
- Postmortem Distribution of Cyanide in 21 Victims of Cyanide Poisoning: Comparison of cYanide Concentration in Heart Blood, Peripheral Blood and Gastric Contents
- KM212 Inhibits Rat Vascular Smooth Muscle Cell Proliferation and Migration In Vitro and Improves Neointima Formation after Balloon Injury In Vivo
- Method Development for the Profiling Analysis of Endogenous Metabolites by Accurate-Mass Quadrupole Time-of-Flight(Q-TOF) LC/MS
- Burden of Disease due to COPD
- Search for Neuroprotective Substances Regulating Cytotoxicity Induced by Glutamate and Oxidative Stress
- Interleukin-6 Gene Deficiency Potentiates Age-Dependent Cognitive Impairments In Mice
- Bioavailability and Toxicokinetics of Citrate Coated Silver Nanoparticles in Rats
- Effects of Herbimycin-A on the Metabolism of Amyloid Precursor Protein
- Nitric Oxide Production Effect of an Herbal
- Anti-fatigue Effects of the Fermented GOG
- Molecular Docking Studies of Phlorotannins from Ecklonia stolonifera with BACE1 Inhibitory Activity
- Isolation and Quantitative Analysis of Peroxynitrite Scavengers from Artemisia princeps var. orientalis
- Effect of PLX-SA, a Composition of Herb Extracts, on Atopic Dermatitis in BALB/c and NC/Nga Mice
- Neuroprotective Effect of Persimmon Peel Extracts in Neuronal Cells
- Structure of New Phenylpropanoid Ester from the Rhizomes of Zingiber officinale
- Metabolomic Application to the Discrimination of Scrophularia spp. According to the Geographic Origin
- Inhibition of DNA Topoisomerases I and II and Cytotoxicity of Ulmus davidiana var. japonica
- Simultaneous Quantitation of Biomarkers for the Herbal Medicine, Polygoni Multiflori Radix by High Performance Liquid Chromatography
- The Effects of Honeybee Venom in Human Skin Wound Healing In Vitro
- Discrimination of Artemisia asiatica According to Geographic Origin with Near-Infrared Spectroscopy (NIRS) Combined with Multivariate Analysis
- In Vitro Effects of Butanol Extract of Arctium lappa L. on Anti-allergic Inflammation
- Antifibrotic Compounds from Liriodendron tulipifera Leaves and Twigs
- Quantitative Analysis of Dioscin from African Dioscorea species
- Determination of Lamivudine in Human Plasma by Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic Study
- Determination of a Peroxisome Proliferatoractivated Receptor γ Agonist, KR-62980 in Rat Plasma by Liquid Chromatography-tandem Mass Spectrometry
- A Rapid and Sensitive Determination of Rosuvastatin in Human Plasma by Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic Study
- Preparation and Characterization of a Human Serum Albumin-attached Exendin-4 derivative with Extended Hypoglycemia
- An Analytical Method of Bioactive Marker Components from Dipsaci Radix
- Comparison between Charged Aerosol Detection (CAD) and Evaporative Light Scattering Detection (ELSD) for the Analysis of Triterpenoid Saponins from Pulsatilla Koreana
- Simultaneous Determination of Glimepiride and Metformin in Human Plasma by Liquid Chromatography/Tandem Mass Spectrometry with Electrospray Ionization
- Antioxidant and Anti-diabetes Activities of Diarylheptanoid Isolated from Alnus hirsuta
- Preparation and Characterization of PEGylated TRAIL Loaded PLGA Microsphere for Dual Long Acting Effect
- Development of Novel Sodium Fusidate-loaded Wound Dressing with Polyvinyl Alcohol and Sodium Carboxymethylcellulose
- Preparation of Sustained-Release Tablet with Cilnidipine inclusion complex
- Effects of Solid Carriers on the Solubility and Oral Bioavailability Enhancement of Flurbiprofen Solid -SEDDS
- Formulation Strategies for Improving Solubility of Paclitaxel Using Surface-Modified Solid Lipid Nanoparticles with Cyclodextrin
- New Alkaloids Isolated from a Solitary Tunicate
- Decursin Inhibits Vasculogenesis in Tumorigenesis by Suppression of Endothelial Progenitor Cell Differentiation and Function
- Chemical Constituents of Chrysanthemum zawadskii var. latilobum
- A New Anti-allergenic Sesquiterpene from the Rhisomes of Cyperus rotundus
- Drug-Interaction Study of Phenolsulfonphthalein with Propylenglycol
- Solubilization of Amphotericin B by Inclusion Complex and pH-Sensitive Degradation Using Multiblock Copolymer Gel Formulation
- Comparative Evaluations of Drug Use for Outpatients Prescribed by General Practitioner or Specialized Practitioner in ENT Area
- Cost-Effectiveness Analysis of Erlotinib versus Docetaxel as a Second or Third Line Treatment of Non Small Cell Lung Cancer in Korea
- Pharmacokinetics of Itraconazole in Diabetic Rats
- Evaluation of Drug Use Causing Delirium and Drowsiness in Elderly Patients of Korean
- Development of Therapeutic Duplication Criteria for Computerized Drug Utilization Review Screening
- Concurrent Drug Utilization Review: US Perspective
- Budget Impact Analysis of Oral Antiviral Agents for the Treatment of Chronic Hepatitis B in South Korea
- Models of Centralized and Joint Institutional Review Boards for Multicenter Clinical Trials
- Glyceollins Inhibits Angiogenesis and Tumor Growth by Decreasing Hypoxia-inducible Factor-1α
- The Improvement Effects on Memory and Learning by Soyasaponin B from Glycine max
- Isolation and Identification of Chemical Constituents from Leonurus japonicus
- The Anti-oxidative and Anti-inflammatory Activity Effects of Phenolic Compound from the Barks of Quercus gilva Blume
- Antifibrotic Activity of Chemical Constituents from Betula platyphylla Barks on Hepatic Stellate cells
- Phytochemical Constituents of Cynanchum paniculatum
- New Iridoids and Phenylpropanoids from Aerial Parts of Caryopteris incana (Thunb.) MIq.
- Phytochmical Constituents of the Rhizomes of Anemarrhena asphodeloides
- Biologically Active Compounds from An Endozoic Fungus Associated with the Giant Jellyfish Nemopilema nomurai
- GSK-3b-Nrf2 Signaling Pathway for Neuroprotection in Alzheimer’s Disease
- A Triterpenoid Limonoid, Obacunone Isolated from Phellodonri Cortex Exerts Anti-inflammatory Activities through NF-kB DNA Binding Inhibition in LPS-stimulated RAW264.7 Macrophages
- Anticancer Activity of Kochiae fructus in HT-29 Human Colon Cancer Cells
- Glycyrol Induces Apoptosis on Human Jurkat T Cell Leukemia through Fas-FasL/Caspase-8 Pathway
- Chemical Constituents of Betula platyphylla and Their Inhibitory Activity on Lipopolysaccharide-Induced Nitric Oxide Production in BV2 Microglia
- Dammarane-type Glycosides from Gynostemma pentaphyllum and Their Effects on IL-4-induced Eotaxin Expressionin Human Bronchial Epithelial Cells
- Antioxidative Activities of Compounds from Artemisia annua L.
- Neuroprotective Effects of Active Compounds in Triticum aestivum L. against β-Amyloid-induced Oxidative Cell Death and Scopolamine-caused Memory Impairments
- Validated LC-MS/MS Method for Simultaneous Quantification of Telmisartan in Human Plasma
- Inhibitory Effects of Inducible Nitric Oxide Synthase (iNOS) mRNA Expression and Nitric Oxide(NO) Production by Myrrh Oil
- Classification of Rhei Rhizoma using Partial Least Squares Discriminant Analysis of Bioactive Components by HPLC
- A Rapid and Sensitive Determination of Olmesartan Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic Study
- Screening of Small Molecules to Discover a Potent Inhibitor of ESX-Sur2 Interaction
- Effects of Myricetin, an Antioxidant, CYP2C9, 2D6 and P-gp Inhibitor in vitro, on the Pharmacokinetics of Carvedilol in Rats
- The Establishment of Analytical Method of New Restricted Preservatives in Cosmetics
- Chiral Separation of Decursinol Angelate and Decursin Derivatives on OD-H Column by HPLC
- Exendin-4 Derivative Conjugated with Palmitylamine Modified-PEG as an Injection-Based Long-Acting Anti-Diabetic Treatment
- In-line Monitoring of the Polymorphic Transformation via NIRS
- Determination of Stability Constants for Fluvastatin Enantiomer and Hydroxypropyl-β-cyclodextrin Complex
- Preparation of Nadolol Enantiomers using (-)-MCF as a Chiral Derivatizing Reagent
- Structural Analysis of Tumor Suppressor TGF-β Stimulated Clone 22 (TSC-22)
- Effects of Process Parameters on the Emulsion Droplet Size and Distribution Using SPG Membrane Emulsification
- Development and Validation of Dissolution Tests for Trimetazidine Hydrochloride Tablets in Korea Pharamceutical Codex
- Niacinamide as a Crystal Growth Inhibitor for the Preparation of Megestrol Acetate Nanopowder by Liquid Precipitation and Spray Drying
- Effect of Chemical Conjugation on Inhibiting Peptide Acylation in PLGA Matrix
- A New Method to Prepare Nanosuspensions for Ocular Delivery
- Pharmacokinetic Study of Rosiglitazone in Diabetes Animal Model
- Method Validation of Everted Gut Sac Technique for Glucose Intestinal Absorption
- Improved Dissolution of Biochanin A, a Bioflavonoid, via the Preparation of Solid Dispersion
- Enhanced Solubility and Oral Bioavailability of Silymarin by Using Membrane Emulsification Technique
- Physical Property Modification of Glimepiride Using Various Recrystallization Processes
- Conformational Changes in Escherichia coli Tryptophan Synthase β2 Subunit
- Effects of Silybinin, an Antioxidant, on the Pharmacokinetics of Losartan in Rat.
- Physicochemical Characterization of Tacrolimus Sustained-release Tablet Prepared by Solubility-enhanced Solid Dispersion System
- Preparation of Porous Poly(lactic-co-glycolic acid) Microspheres by pH Control Using Gelatin Porogen
- 2009 Summarized Report of ADME/Tox Screening Data in KRICT
- Apigenin, an Antioxidant, Enhanced the Bioavailability of Etoposide in Rats
- Pharmacokinetic Characteristics of Lornoxicam in relation to CYP2C9*3 Allele in Healthy Korean Subjects
- The Necessity of Vaccine Education for Pharmacists and Development of a Vaccine Leaflet for Patient Counseling
- The Pharmacy Health Promotion Program in Major Countries
- Review of Implementation of Prescribing Incentive Scheme in UK
- Study to Improve Medicine Approval System through Comparisons with Major Advanced Countries
- Modeling the Arrhythmogenic Property of Levofloxacin in Guinea-pig
- Study of the Guideline for Clinical Evaluation of Gastroenterology Drug
- Preparation and Characterization of Gemcitabine Micro/nanoparticles for Oral Delivery
- Anti-obesity Effect and Action Mechanism of Cinnamaldehyde in High Fat Diet Induced Mice
- New Small Molecules Targeting Hypoxia-inducing Factor-1 Signaling and Angiogenesis
- Antitubercular Nitroimidazoles : Aerobic and Anaerobic Activities
- Challenges and Opportunities in Biosimilars
- Analysis of Coding of Fear Memory in the Amygdale with Temporal and Cellular Resolution
- Novel DGAT Inhibitors as Potential Anti-Obesity Agents
- Design and Synthesis of Small Molecule Ligands for Oncogenic Ras Proteins
- Development of Long-Circulating Pegylated Granulocyte Colony Stimulating Factor
- Neurovascular and Neurodegenerative Diseases of Retina
- Educational Significance of PBL, and the Management of PBL in Medical School
- Role of the Extended Aamygdala in Pain-Induced Aversion
- Agonist-Induced Endocytosis and Receptor Phosphorylation Mediate Resensitization of Dopamine D2 Receptors
- Neuropsychopharmacological Potentials Modulated by Dextromethorphan Analogs
- Capillary Separation Techniques of Protein Drugs
- Development of DA-7218, a Next-Generation Oxazolidinone
- Glycan Microarrays for Functional Glycomics
- Hit to Lead Studies Based on Natural Product Prototypes
- Neuroprotective Effects of the Herbal Ethanol Extracts in 6-hydroxydopamine-lesioned Rat Model of Parkinson's Disease
- Effect of Sibutramine HCl on Cardiac hERG K+ Cannel
- Role of Ceruloplasmin in the Kainate-Induced Excitotoxicity
- Comparison of Antiangiogenic Activities of Ethanol Extracts Prepared from Several Natural Products of Plant Origin
- Role of Klotho Gene in the Cognitive Impairment
- The Beneficial Effects of Telmisartan Combined with Lacidipine on Hypertension and Other Risk Factors for Cardiovascular Disease
- Protective Effects of Neohesperidin and Poncirin Isolated from the Fruits of Poncirus trifoliata on Potential Gastric Disease.
- MeOH Extract of Hura crepitans L. Inhibits LPSInduced Inflammatory Response via Blocking of NF-kB Activation in Macrophages.
- Melittin, a Peptide Isolated from Bee Venom Toxin, Prevents Prostate Cancer Cell Growth through Modulation of NF-κB/caspase Pathway
- Anti-allergic Effect of Essential Oil from Thujopsis dolobrata by Decreasing Beta-hexoaminidase from Allergen induced RBL-2H3 Cells
- Effect of Plant-Derived Activators for AMP-Activated Protein Kinase Signaling in Metabolic Disease Animal Models
- CWP231A, First-in-Class Wnt Signaling Inhibitor for Cancer
- Lentiviral Mediated Stable Knockdown of Nrf2 Sensitizes ErbB2 Overexpressing Ovarian Cancer Cell Towards Docetaxel
- Simultaneous Analysis of Bioactive Metabolites from Rehmannia glutinosa by HPLC-DAD-MS/MS
- Drug Development with Korea Chemical Bank
- Synthesis of Anti-inflammatory Aurone Derivatives
- Norcarotenoid Glycosides from the Roots of Rehmannia glutinosa
- Solution Structure and Sequence Specificity of a Nucleic Acid Binding Protein CUGBP1ab
- Determination of Azelastine in Human Plasma by Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic study
- Effects of Acute Renal Failure Induced by Uranyl Nitrate on the Pharmacokinetics of Liquiritigenin and Its Two Glucuronides, M1 and M2, in Rats
- Discrimination of Genotoxic and Nongenotoxic Carcinogens by Analyzing Microarray Gene Expression Data
- Triolein Emulsion Increases Vascular Permeability Transiently
- Research to Find New Bioactive Compounds from Indonesian Plants
- CDKs and Neuronal Death in Stroke
- What's New in the Drug Regulatory System : Incrementally Modified Drugs ?
- Thermodynamic Equilibration in Pd(0)-catalyzed Interconversion of Highly Constrained [2.1.2] Bicyclic Lactones: Its Mechanistic Investigation
- Structural requirements of Novel Chromone Analogs for their Inhibitory Activity Against Interleukin-5
- HS-104, a Novel Phosphatidylinositol 3-Kinase Inhibitor, Eicits Anticancer Activities in Human Liver Cancer Cells.
- Analytical Methods for Determining Effective Ingredients of Hair Nourisher Products
- Differential Effect of Genetic Variants of NTCP and OATP1B1 on the Uptake of HMG-CoA Reductase Inhibitors
- Development of a Micellar Electrokinetic Chromatography Method for the Determination of the L-enantiomer of Nateglinide
- Propenone Derivatives Inhibit Inflammatory Process In Vitro and In Vivo
- Genotoxic Effects of Silver Nanoparticles Using Bacterial System and Mammalian Cell System
- Inhibitory Effect of IL-32γ on the Growth of Colon Cancer Cell through Inhibition of NF-κB and STAT3 Signals
- Pathological Role of Pin1 in the Intimal Hyperplasia
- Study of Action Mechanism of IN-2001, a HDAC Inhibitor for the Breast Cancer Metastasis
- Alteration of Sulfur Amino Acid Metabolism between Human Breast Cancer Cells and Adriamycin Resistant Breast Cancer Cells
- Plasma Homocysteine Levels are Increased in C57BL/6 Mice Fed with High Fat Diet
- Lindera obtusiloba BL. 70% EtOH Extract Induced ERK Activation Inhibits Melanin Synthesis in Mouse B16F10 Melanoma Cells
- Antioxidation and Detoxification Potential of Wheat (Triticum aestivum) Sprout Juice in Korean Women
- Genotoxicity and Cytotoxicity of Titanium Dioxide Nanoparticles under UVA in Peripheral Blood Lymphocytes
- Selective Inhibition of Activated Stellate Cells and Protection from Carbon Tetrachloride-induced Liver Injury in Rat by a New PPARγ Agonist KR62776
- Bisphenol A Impairs Hippocampal Neurogenesis in Young Mice
- 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Induced Synaptic Disruption in Differentiated SH-SY5Y Cells
- Possible Role of the PI3kinase on the Mx1 Protein Translation and Antiviral Activity of Interferon-omegastimulated HeLa Cells
- Regulation of Autophagic and Apoptotic Cell Death by Novel Autophagy Regulators, Oxi Gene Family, in Dopaminergic Neurons
- Lycopene Inhibits Proliferation, Invasion and Migration of Human Breast Cancer Cells
- Propyl Gallate Induces Apoptosis and Cell Cycle Arrest in Activated Rat Hepatic Stellate Cells
- CoMFA on the Antiproliferative Activity of NSubstituted 2-Amino-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole Analogues against Bladder and Rectal Cancer
- Torilin from Torilis japonica Inhibiting Melanogenesis through the Down-Regulation ofMITF by Increasing ERK Activity in B16 Melanoma Cells.
- Establisment of Rapid Sterility Test for Cell Theraphy Products
- A Novel Extracellular Lipase of Streptomyces sp. CS326 Strain Newly Isolated from Korean Soil
- Purification and Characterization of a Fibrinolytic Enzyme from a Newly Isolated Streptomyces Strain
- Akt inhibitors, Alkylphospholipids, Induce Cell Death of HIV-1 Infected Macrophages
- The Antiosteoporotic Activity of Peptides in Bombycis Corpus
- Characterization and Application of a Lipase Produced by a Soil Acinomycetes
- Enzyme Activities of Bacteria Isolated from Human Feces
- Integrating Natural Products and Chemical Biology to Discover Drug Leads from Marine Cyanobacteria
- Novel Gastroretentive Drug Delivery System
- 5,5'-Substituted Indirubin-3'-oxime Derivatives as Potent Cyclin-Dependent Kinase Inhibitors with Anti-Cancer Activity
- Guideline on the Common Technical Document for NDA
- Directions for Establishment and Revision on Pharmaceutical Safety Standards
- Points to Consider in Review and Approval of New Pandemic Vaccines
- The Inflammasome and Therapeutic Interventions in the Sepsis
- Reproductive and Developmental Toxicity of Dioxin through Damage on Fetal Gonadotropins
- Constitutive Expression and Chemical-mediated Induction of Hepatic Cytochrome P450 1A (CYP1A) Subfamily Enzymes
- Bacteria-Derived Extracellular Vesicles as Vaccines for the Prevention of Nosocomial Infections
- Natural Therapeutic Magnesium Lithospermate B Potently Protects the Endothelium from Dysfunction in Diabetes
- The Effect of Selective Estrogen Receptor Modulators on the Breast Cancer Cells, MCF-7 cells and Tamoxifen-Resistant Cells
- Neuroprotective Effects of the n-Hexane Fraction from Laurus nobilis Leaves in Dopamine-Induced Cells and Animal Models of Parkinson’s Disease
- Mutation of Presenilin 2 Is Associated with Decreased Lung Tumorigenesis through Inactivation of Notch 2 Signaling
- Inhibitory Effects of PES0409 on PDGF-BB-induced Proliferation of VSMCs through Blocking PDGF-Rb Phosphorylation
- Anti-gastritic Effect and Anti-oxidant Activities of Chenopodium album Linne Extract and Fractions
- Epithelial-mesenchymal Transition in Tamoxifenresistant Breast Cancer Cells
- Therapeutic Effect of Korean Red Ginseng against Noise-Induced Hearing Loss in Animal Model
- Protection of Trimethyltin Neurotoxicity by Interleukin-6Gene
- Inhibition of SREBP-1c-mediated Hepatic Steatosis and Oxidative Stress by Sauchinone, an AMPK-activating Lignan in Saururus chinensis
- SNP1223 Inhibits Hydrogen Peroxide-Induced Apoptosis in SH-SY5Y Cells
- Exposure to Methylphenidate Alters Place Preference and Self-administration in Rats: Strain-specific Responses in Both Parameters
- Inhibitory Activities of Some Selected Antioxidant Compounds on the Chick Chorioallantoic Membrane (CAM) Angiogenesis
- Alterations in Intestinal Bacteria Metabolism Affect the Pharmacokinetic Property of Hesperidin
- Role of NRF2 Signaling in Tumor Angiogenesis of Colon Cancer Cells
- Role of the NRF2 System in TGFβ1-induced Epithelial-mesenchymal Transition in Rat Renal Epithelial Cells
- The Study of Radiosensitization of Tumor by Natural Small Molecules
- The Evaluation Methods of Anti-platelet Agents, and the Assessment of Trifusal on Anti-Platelet Aggregation Activity in Human Volunteers
- Neurotoxic Effects of Berberine in 6-Hydroxydopamine-Lesioned Rats Treated with Chronic L-DOPA
- Anti-Breast Cancer Effects of Propolis on ERPositive and ER-Negative Breast Xenograft Model
- Anti-inflammatory Activity of Methanol Extract of Elaeocarpus petiolatus (Jack) Wall. in Raw264.7 Macrophages
- The Protective Mechanism of QGC on Indomethacin-Induced Gastric Damage in Rats
- SPA019, a Natural Compound Reverses Alcoholic Fatty Liver by Inhibiting the Liver X Receptor alpha Mediated Sterol Regulatory Element Binding Protein-1c Regulatory Pathway
- Metabolomic Analysis of S-Containing Substances in Mouse Liver Treated with Silymarin Acutely
- Mechanism of Nephrotoxicity and Renal Stone Formation in Sprague-Dawley Rats Treated with Melamine and Cyanuric Acid
- A Novel Epoxypropoxy Flavonol Derivative Topoisomerases II Inhibitor, MHY-336, Induces Apoptosis in Prostate Cancer Cell
- The Carcinogenicity Evaluation of Herbal Medicines
- Reproductive Ototoxicity of TBBPA in Rat Offsprings
- Effects of Medicinal Herbs and Their Components on the Steatogenic Hepatotoxicity
- Immunomodulating Effects of Chaga Mushroom (Inonotus obliquus) in OVA-Sensitized Balb/c Mice
- Immunotoxicity Assessment of Common Traditional Korean Medicines
- Lipolysis Effects of Lancemaside A and Aglycon from Codonopsis lanceolata Water Extract in Primary Cultured Adipocytes from Obese Rat fed High Calorie High Fat Diet
- Effect and Mechanism of Morus bombycis Koidzumi on Collagen-induced Arthritis in Mice
- Determination of Some Preservatives in Distributed Cosmetics in Seoul Area
- Atrial Local Ca2+ Signaling and Inositol 1,4,5-Trisphosphate Receptors
- Effects of the Anthocyanin Isolated from the Purple-Fleshed Sweet Potato on Dimethylnitrosamine-Induced Liver Fibrosis and PDGF-BB-Dependent Signaling Pathways in Hepatic Stellate Cells
- Chemopreventive Effects of Baicalein on Dextran Sulfate Sodium (DSS)-induced Mouse Colitis
- 4-(6-Hydroxy-2-naphthyl)-1,3-bezendiol: A Potent, New Tyrosinase Inhibitor
- Cloning and Expression in Pichia pastoris of a New Cytochrome P450 Gene from a Dandruff-Causing Malassezia globosa
- Smurf2-Mediated Runx2 Degradation Is Regulated by AKT during Osteogenesis
- Autoacetylation of Human Arrest Defective 1 is Required for Tumor Growth
- Interactions of Tricyclic Isoxazoles with α2c-Adrenoceptor by Homology Modeling
- The Alpha-Helical Tip Region of MacA is Important in the Assembly of TolC in the MacAB-TolC Pump.
- Inhibitory Effect of Chalcone Derivative (JSH 03-1-10) on Lipopolysaccharide-Induced NF-kB Activation and iNOS Expression in Macrophages
- High Fat Diet Impairs Adult Hippocampal Neurogenesis: Involvement of Lipid Peroxidation and Brainderived Neurotrophic Factor
- Antioxidative and Antiinflammatory Effects of Cabbage Extracts
- Wip1 Directly Dephosphorylates Gamma-H2AX and Attenuates the DNA Damage Response
- Predicting Idopathic Toxicity of the Anticancer Agent Cisplatin with a Pharmacometabolomic Approach
- TAZ as a Novel Enhancer of MyoD-mediated Myogenic Differentiation
- Oral Administration of 2-Docosahexaenoyl Lysophosphatidylcholine Displayed Anti-Inflammatory Effects on Zymosan A-induced Peritonitis
- Bacterial Reverse Mutation Test of Bidens pilosa
- Biochemical Activities of Feline Foamy Virus Integrase Protein
- RtxA1, a RTX Toxin of Vibrio vulnificus Causes a Programmed Necrotic Cell Death through VDAC-Mediated Mitochondrial Dysfunction.
- Inhibitory Effect of In Vitro Cultured NK Cells on the Growth of Breast Cancer
- Effects of Klebsiella pneumoniae and Bifidobacterium adolescentis in TNBS-induced Colitis Mice
- A New DNA Building Block, 4'-Selenothymidine: Synthesis and Its Modification to 4'-Seleno-AZT as a Potential Anti-HIV Agent
- Synthesis of L-2’-Methylnucleoside Derivatives as Potential Anti-HCV Agent
- Cordycepin Inhibits Diabetes Relating Genes through Suppression of Inflammatory Cytokines
- Anti-inflammatory Activity of New Compounds KNU00146 by STAT-1/JAK2-mediated Inflammatory Responses Inhibition in LPS-activated Macrophages
- Growth Promoting Role of Pharma in Future Healthcare Business
- Broccoli Extract and Antioxidation
- Acai Berry(Euterpe oleracea) Inhibits Melanogenesis in B16F10 Cells
- Preparation and Characterization of PEG-heparinbased Nanoparticles with Improved Stability for the TRAIL Delivery
- Interleukin-33 Stimulates Formation of Functional Osteoclasts from Human CD14+ Monocytes
- Tanshinone IIA Enhances BMP-2-Stimulated Commitment of C2C12 Cells into Osteoblasts via p38 Activation
- Protein Kinase C-δ Regulates the Stability of Hypoxia-Inducible Factor-1α under Hypoxia
- Novel Cinchona-Aminobenzimidazole Bifunctional Organocatalysts
- Migration Order of Sibutramine Enantiomers in Capillary Electrophoresis
- Regulatory Issues in Developing of Biosimilars
- Analytical Pathways For Biosimilar Development
- Synthesis and Antitumor Activity of seco-Duocarmycin Analogs
- Resveratrol and It's Analogue, HS-1793, Inhibit Hypoxia-inducible Factor-1α and VEGF Expressions in Human Hepatocellular Carcinoma Cells
- Interleukin-11-modified Liposomes for Cancertargeted Delivery
- Monitoring of Some Bioactive Components of Lonicerae Forium et Caulis Samples Collected from Korea and China
- A New Sesquiterpenoid from Angelica koreana
- Analytical HPLC-MS/MS Method for the Determination of Pramipexole in Human Plasma and Its Application to a Pharmacokinetic Study
- Akt-targeted Immunosuppressive Effect of HQ and Its Derivatives
- Synthesis and Docking Study of 12-Oxobenzo[c]phenanthridinones and C4-Substituted 3-Arylisoquinolines as Topoisomerase 1 Inhibitors
- Ajoene, a Stable Garlic Byproduct, Has an Antioxidant Effect in Hepatocytes through Nrf2-Mediated GCL Induction
- Phenylthioureas are the Inhibitors of Melanogenesis in Melanoma B16 Cells
- Design of D-ring removed Estradiol Analogues as SERMs
- Cliona Celata Extract Inhibits Lipopolysaccharide-Induced NO Production and iNOS Expression Require Inhibition of NF-κB Activation in Murine Macrophage RAW264.7 Cells
- Preparation and Characterization of Human Serum Albumin Nanoparticles Conjugated with TNF-related Apoptosis Inducing Ligand (TRAIL)
- Physicochemical Characterizations and Pharmacokinetic Studies of Two Isoflavone Extracts
- Synthesis and Structural Optimization of Multiple H-Bonding Region of Diarylalkyl (Thio)amides as Novel TRPV1 Antagonists
- Biological Evaluation of Isoegomaketone Isolated from Perilla frutescens and its Synthetic Derivatives as Antiinflammatory Agents
- Design and Synthesis of 2,3-Dihydrobenzofuran-2-carboxylic Acid N-(Substituted)phenylamide Derivatives as NF-κB Inhibitors
- Synthesis of Novel Cinnamoylsalicylamide Analogues and their Inhibitory Activity of Wnt/β-catenin Signaling Pathway
- New Secondary Metabolites Production by Microbial Co-Culture
- Anti-Tumorigenic Activity of Sophoflavescenol against Lewis Lung Carcinoma In Vitro and In Vivo
- Effect of UG0712 on Forced Swimming Capacity in Mice
- Enrichment of Sphingosine-1-phosphate using Immobilized Metal Affinity Chromatography-Mass Spectrometry techniques in Biological Samples
- Analysis of Impurities in Methamphetamine Crystals Seized in Korea by Combination of Liquid-Liquid Extraction (LLE) and Automated Headspace Solid-Phase MicroExtraction (HS-SPME) Method
- Microchip Electrophoresis for Monitoring PEGylation of Proteins
- Effects of Specific Bifidobacterium Strains Isolated from Korean Healthy Adults on the Growth Responses of Staphylococcus aureus
참고문헌
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!