두경부 편평상피세포암종에서 18FDG−PET을 이용한 방사선치료 반응평가

• 영문명: Evaluation of the Response of Radiotherapy to Squamous Cell Carcinoma of the Head and Neck using 18 FDG−PET
• 발행기관: 대한두경부종양학회
• 저자명: 이상욱(Sang wook Lee) 김재승(Jae seung Kim) 류진숙(Jin sook Ryu) 이병용(Byong yong Yi) 김종훈(Jong hoon Kim) 안승도(Seung do Ahn) 신성수(Seong soo Shin) 김상윤(Sang yoon Kim) 남순열(Soon yuhl Nam) 송시열(Si yeol song) 윤상민(Sang min Yoon) 박진홍(Jin hong Park) 김성배(Sung bae Kim) 최은경(Eun kyung Choi)
• 간행물 정보: 『대한두경부종양학회지』제19권 제1호, 58~62쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2003.05.30

영문 초록

Purpose: To evaluate the efficacy of positron emission tomography with 2-[F-18] fluoro-2-deoxy-D-glucose in discrimination of response in the nasopharyngeal carcinoma patients who treated with radiotherapy. Methods and Materials: Twenty-four patients who underwent FDG-PET scan before and after radiotherapy for no disseminated head and neck carcinoma at the Asan Medical Center between August 2001 and September 2002 were evaluate by prospective analysis. First FDG-PET scan performed before radiotherapy within 1 month, and second FDG-PET scan performed 1 month after radiotherapy. FDG-PET images were analyzed by standard uptake value (SUV). Follow-up period was more than 6 months. Results: The pretreatment SUV was 3.4-14.0 (median: 6.0) and posttreatment SUV was ground level-7.7 (median: 2.0). The overall sensitivity and specicity of FDG-PET to evaluate residual tumors in the nasopharyngeal carcinoma patients were 94% and 94%. Conclusion: FDG-PET is effective in evaluation of radiation response in the nasopharyngeal carcinoma. We think that the timing of one month after finished radiotherapy FDG-PET scan was not too fast to evaluation of radiation response.

목차

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대상 및 방법

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키워드

방사선 치료 두경부 편평세포암종 FDG-PET Radiotherapy Head and Neck Squamous cell carcinoma