학술논문
Quantitative Analysis of Major Toxic Components from Strychni Semen by HPLC
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- HUR Sun-Jung KIM Kyoung-Young LEE Kyoung-Tae KIM Sun-Gun MOON Ye-Ji HAN Chi-Su KWON Oh-Jung PARK Taesim WHANG Wan-Kyunn
- 간행물 정보
- 『추계총회 및 학술대회』(2008년) vol.2, 283~283쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2008.10.30
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- Calmodulin-dependent Kinase II Regulates Osteoblast Differentiation
- Predictive Models of Cannabinoid-1 Receptor Antagonists Derived from Diverse Classes of Antagonists
- Discovery and Optimization of Novel Histone Deacetylase Inhibitors by Computational Drug Design Methods
- Synthesis of Wogonin Analogs and Their Biological Effects
- Synthesis and Evaluation of 7,8-Dihydro-6H-[1,3] dioxolo[4,5-g]chromene-6 -carboxylic Acid N-Substitutedphenylamide Derivatives as Inhibitor of NF-kB Activity
- Diketopiperazine derivatives from a Tropical Sponge Associated Marine Actinomycete
- Variation of Acharan Sulfate and Monosaccharide Composition and Analysis of Neutral N-Glycans in African Giant Snail (Achatina fulica)
- Determination of S-HT2c Agonist KKHQ80114 in Rat Plasma and Urine by Gas-Chromatography /Mass Spectrometry and its Pharmacokinetics in Rats
- A Lack of Pharmacokinetic Alteration of Doxorubic in by Naringin , Nanngenin , and Quercetin in Rats
- Use of Over The Counter Drugs and Health Supplements in Korean Geriatrics
- Antiapoptotic Fusion Protein Delivery Systems
- The Functional Role of H2 -M3 during Bacterial Infection
- KFDA's Approach to International Harmonization Review on Drug Safety and Efficacy
- Good Manufacturing Practice & Quality System
- Development of Self-Assembled Nanoparticles for Targeted Cancer Therapy
- Itraconazole Solubilized in Cream Formulation for Topical Delivery
- Current Status in the Development of Anti-diabetic Agents
- Increased Angiogenesis in Chemotherapy-Resistant Breast Cancer Cells
- Protective Effects of Fermented Ginseng through Activation NF-kappaB on Pancreas β-cell Death Induced by Streptozotocin
- Enalapril Inhibits Catecholamine Secretion from the Isolated Rat Adrenal Medulla
- IL-32y, a New Determinant Cytokine in the Cancer Cell Growth
- Compound CInhibition of Adipocytes Differentiation: Role of an Increase in p21 in the Suppression of Preadipocyte Clonal Expansion
- Protein Tyrosine Phosphatase IB Inhibitory Activity of Vietnamese Medicinal Plant Morus alba
- Cancer Cell Growth Inhibition by 4-O-methylhonokiol a Novel Neolignan Compound Isolated from Magnolia officinalis
- Inhibitory Effects of Ochnaflavone on the Proliferation of HCT-15 Human Colon Cancer Cells
- Metabolomic Analysis after Atorvastatin Administration in High Lipidemia Rats
- Biological Activities of Korean Muskmelon
- Genotoxic Effects and Oxidative Stress Induced by Silver Nanoparticles in BEAS-2B Cells
- Direct Quantification of Photosensitizer Druginduced DNA Single Strand Breaks Using Oligonucleotide Chip
- The Whitening Effects of Acai Berry Extracts on the B16F10 Melanoma Cell
- Viagra Can Induce Hearing Impairment in Mice
- Effects of Oral Morin on the Bioavailability of Doxorubicin for Oral Delivery in Rats
- Apicidin Blocks SK-OV-3 Cells Migration and Invasion through the Histone Deacetylase 4 Silencing
- Involvement of AMP-Activated Protein Kinase/ACC Pathway on the Fatty Liver Induced by Orotic Acid
- Role of Matrix Metalloprotease-9 in ATP-induced Microglial Migration
- Prodynorphin Gene Depletion Potentiates Nalbuphine-Induced Drug Dependence in Mice
- Anti-melanogenesis Effect of Sulforapharne on B16F10 Mouse Melanoma Cells
- Anti-Inflammatory Activity of PectoUnarigenin and Pectolinarin Isolated from Cirsium chanroenicum
- Expression and Purification of Human Papillomavirus Type 58 Ll Protein from Saccharom yces Cerevisiae
- Synthesis of (+)-Decursinol Isomer of 8-Hydroxy-7.7-dimethyl-8,9-dihydropyrano[2,3-g]coumarin from Hydroquinone
- Synthesis of Novel 4'-ethenyl or Ethynyl Carbocyclic Nucleoside An alogues of Stavudine
- New Meroditerpenoids from the Brown Alga Sargassum siliquastrum
- Total Synthesis and Anticancer Activity of Glycolipid
- Inhibitory Effect of Nyazol from Anemarrhena asphodeloides on the Growth of Human Cancer Cells
- Marine Actinomycetes: A New Source of Angiogenesis Inhibitors
- New Facile Way to Synthesis New Isoflavones for the Inhibitor! of Bioactivity of Interleukin-5
- Inhibition of bFGF-Induced Angiogenesis by Xanthorrhizol, a Sesquiterpene Isolated from Curcuma xanthorrhiza
- Quantitative Analysis of Major Toxic Components from Strychni Semen by HPLC
- A New Ergostane-Type Sterol from the Liquid Cultured Ganoderma appianatum
- Two New Flavonoid Glycosides from Salvia plebeia
- Two new oligostilbenes from Caragana sinica
- Anti-inflammatory Activity Change of Processed Gardeniae Fructus
- A New Antimalarial Polyether from a Marine Streptomyces sp. H668
- Galloyl Glucoses from the Seeds of Comus officinalis with Inhibitory Activity on Protein Glycation
- The Estrogenic and Anti-estrogenic Action of Epimedii Herbain Pubertal Female Rats
- Development of an Analytical Method for the Determination of Residual Nine Cephalosporins in Milk using LC-MS /MS
- Determination of Leflunomide Metabolite , A771726 in Human Plasma by Semi-micro HPLC/UV
- Survey of Tar Colors in Syrup Preparations for Children
- Analysis of Narcotics in Various Hallucinant Herbal Drugsusing TLC and GC/MS
- Development and Validation of a Method for Quantitative Determination of Alendronate in Human Plasma by High Performance Liquid Chromatography-Fluroscence Detector Spectrometry
- Pharmacotherapy of Ursodeoxycholic Acid in Preterm Infants Associated Cholestasis with Parenteral Nutrition
- Action of Teucrium japonicum Houttuyn on Mast Cell-Mediated Allergy Model
- The Anti-inflammatory Synthetic 7-0-3"' (C-O-C) Biflavonoids
- Enthopharmacological Roles of Codonopsis lanceolata on GM-CSF Expression in Macrophage-like Cells
- Management of Psychotic symptoms in Parkinson's Disease
- Solvent Effect on N-methoxycarbonyl-L-proIine-N-methylamide
- Drug Reprofiling Platform as a Risk Leverage Strategy in Drug Discovery
- VEGF-Loaded Polymeric Nanoparticles for the Treatment of Ischemic Damage
- KFDA's Regulation on Herbal Medicinal Products Update
- Drug Transport in Drug R& D : from Molecular to Clinical
- Manufacturing Issues of Therapeutic Antibody
- Growth Inhibitory Effects of a Novel A₃ Adenosine Receptor Agonist Thio-CI-IB-IMECA in Human Prostate Cancer Cells
- Anti-proliferation EfTect of Indirubin Derivatives in Multicellular Spheroids Human Colorectal Cells
- Anti-inflammatory Effects of Thiacremonone, a Novel Sulfurcompound Isolated from Garlic via Inhibition of NF-kappaB
- Compound K Stimulates Glucose Uptake through AMPK (AMP-activated kinase) Activation in C2C12 Cells
- Dopamine D₂ Receptor-mediated Regulation of Wnt Signaling
- Induction of Apoptosis by siSMYD3 in the Cervical Cancer Cells
- In Vivo EPR Detected Pathologically Important OH Radical in Lung Injuries Caused by Diesel Exhaust Particles
- Hepatoprotective Effect of the Aralia Continentalis against Carbon Tetrachloride-Induced Liver Injury
- Effects of Aqueous Extract Isolated from Prunella Vulgaris on Macrophage Activation
- Pinl, a Novel Prolyl Isomerase o f p70S6K, Induces Cellular Transformation through Upregulation of AP-1 Activity
- Manassatin A Inhibits CREB-Dependent Melanin Production in 3-Isobutyl-l-IVIethylxanthine-Activated Melanoma Cells
- Quorum Sensing-mediated Triggering of the Insect Innate Immunity
- Probiotic Effect of Bacillus thuringiensis on Experimental Infection with Enterobacteria
- Molecular Analysis of Constitutively Expressed erm Genes from Clinical Gram Positive Cocci
- Design and Synthesis of Azaisoflavones as Inhibitors against the NO Production
- Efficient Synthesis and Anticancer Activity of Chlorin e6
- Biological Activities of Fractions from Methanolic Extract of Picrasma quassioides (D.Don) Benn.
- A Limonoid, Obacunone, Isolated from Phellodendron amurense Inhibits Major Inflammatory Mediators in LPS-Stimulated RAW264.7 Macrophages
- Anti-Oxidative and Nitric Oxide Production Inhibitory Effect of Roots of Ulmus macrocarpa Hance
- Phagocytic Effects of Beta -glucan from Coriolus versicolor are Involved with Dectin-1 Signaling and NOS expression in Macrophages
- Phytochemical Constituents and Biological Activity of Veronicaperegrina
- Antidiabetic and Renal Antioxidative Effect of Phaleria macrocarpa on Alloxan-Induced Diabetic Rats
- Quantitative Analysis of Major Active Components from Prunella vulgaris by HPLC
- Effects of Medicinal Plant Extracts on Promoting Adipocyte Differentiation in Human Bone Marrow Mesenchymal Stem Cells
- Development and Validation of a Method for Quantitative Determination of Aceclofenac and Bioequivalence in Human Plasma by High Performance Liquid Chromatography-UV Spectrometry
- Fatty Acid Profiling and Screening Analyses of Triglycerides and Free Fatty Acids in Algal Lipids by Gas Chromatography
- Identification of Transport Mechanism of Paclitaxel in Syncytiotrophoblast Cells through the Bloodplacenta barrier.
- Effect of Silica and Zinc Oxide Nanoparticles on Cytokine Production and the Viability of Macrophage Cells
- Structure-Activity Relationship Study of Ligands as Inhibitors of the Interaction Between Z a Domain and ZDNA
- Drug Synergism of Rosiglitazone Combined with Fenofibrate for the Treatment of TVpe 2 Diabetes in Mice
- Hepatoprotective Effect of Morin in CCI4-Induced Liver Injury
- Cognitive-enhancing and Anti-oxidant Activity of SNP3878 in Scopolamine-induced Amnesia Mice
- Inhibitory Effects of Lindera obtusiloba BL. Extract on Melanin Synthesis from UVB-induced Pigmentation in C57BL/6 Mice
- Apoptosis-inducing Activity of Compound K through an AMPK in HT-29 Colon Cancer Cells
- Effects of Lycium Fructus Extract on the Lipid Metabolism in the LPS-induced Hepatotoxicity
- Inhibitory Effect of Dibenzobutyrolactone Lignans on PLA 2 Activity and Neutrophil Chemotaxis
- Neuroprotective Effects of CBNU06 against Beta-Amyloid-Induced Toxicity through the Inhibition of NF-kB Signaling Pathway in PC 12 Cells
- Comparison of Cytokine-Induced Killer Cells Generated from Mouse Splenocytes, Bone Marrow Cells and Thymocytes
- Effects of Short-term Baicalin Dietary Supplementation on Fox01 Modulation in Aged Kidney
- The 3D-QSAR Study of Quinoline Salicylic Acids with P-Selectin Antagonistic Activity
- Imine Analogs of Resveratrol Potently Protect PC12 Cells from Oxidative Damage
- Transcriptional Change of Transporters in Tuberculosis Infection
- A bsorption Behavior and Modulation Mechanism of Melatonin by Pharmaceutical Excipient
- Optimization Polyethylene Glycol Size of Antidiabetics PEGylated Peptide Drug for Parenteral Administration
- Involvement of MRPl and BCRP in the Transport of Belotecan and Topotecanin Engineered MDCK Cells
- Combination Therapy of NIK Suppressings iRNAs in Cationic Liposomes with 5-FU for HBV -derived HCC
- In vivo Delivery of Antisense Nucleic Acids via Opsonized Erythrocyte Ghosts for Liver Targeting
- Preparation of Highly Elastic Chitosan IMicros-pheres for Anti-Cancer Embolotherapy
- Effect of Morin on the Bioavaiiability of Losartan in Rats
- A Study on Willingness to Pay for Medication Therapy Management Service of Polypharmacy Patients
- Effects of Injinho-tang on the Biliary Excretion of Phenolsulfonphthalein, a Model Organic Anion Drug
- Development and Validation of Simple and Selective LC-MS /MS Method for Quantifying Baclofen in Human Plasma ; Application to Pharmacokinetic Studies
- Effect of Stilbenoids on PGE₂-Mediated Cell Proliferation and Their Mechanisms of Action in Human Colon Cancer Cells
- 3',5'-Diprenylgenistein Isolated from Tetracera scandens Enhances Muscle Glucose Uptake via AMPactivated Kinase
- Anti-Inflammatory Effect of Chungsim-Yeunja-Tang
- Anti-oxidative Effects of the Quercetin-3-O-β-Dglucuronopyranoside (QGC) on Ethanol-induced Cell Damage in Feline Esophageal Epithelial Cells
- 4,9-Dihydroxy-a-Lapachone Modulates Dopamine Biosynthesis and L-DOPA-Induced Cytotoxicity in PCI2 Cells
- Functional Effects of the Novel Benzofliroindole Analogue (LDD175) in the Contractility of the Rat Urinary Bladder
- Inhibition of Cell Growth by Serine Palmitoyl Transferase Inhibitor in B16F10 Murine Melanoma
- Proteomic Approaches for Bisphenol A Exposure in Second Generation
- Honokiol Reverses Alcoholic Fatty Liver by Inhibiting the Maturation of Sterol Regulatory Element Binding Protein-1 c and the Expression of Its Downstream Lipogenesis Genes
- Characterization of Deoxypodophyllotoxin Metabolism in Rat Liver Microsomes
- Mechanism of Apicidin-induced Cell Cycle Arrest and Apoptosis in Ishikawa Human Endometrial Cancer Cells
- Differential Ceramide Level as a Potential Biomarker for Adipocyte Differentiation in 3T3-L1 Cells
- Antiproliferative Activity of JY0693, a Newly Synthesized Obovatol Derivative, on PDGF-BB-stimulated Rat Aortic Vascular Smooth Muscle Cells
- In Vitro Phototoxicity Test of Chemicals by Using Prediction Models
- Levo-Tetrahydropalmatine Inhibits Apomorphine and Methamphetamine-lnduced Drug Liability: Experiments with DNA and Protein Expression on NMDA and Dopamine Receptor
- Aspirin Blocked Proliferation and Induced Apoptosis in HepG2 Cells through the Activation of Egr-1
- Inhibitory Activation of Dibezobutyrolactone Lignans on LPS-induced NF-kB Activation in RAW 264.7 Macrophage Cells
- Xanthohumoi Inhibits IL-12 Production and Reduces Chronic Allergic Contact Dermatitis
- Immunoregulatory Function of Hot Water Extract from Scutelaria barbata Depending on Macrophage-mediated Immune Responses
- DNA Methylation and Histone H3 Lysine 27 Methylation Regulate CLDN3 Expression in Ovarian Cancer
- Hangover Substances Acetaldehyde and PGE2 Evoked Nociceptive Reponses via TRP Dependent Mechanism
- Report on Pesticide Residues for Kangseo Wholesale Market Vegetables in Summer
- PD-l/PD-Ll Interaction Regulates the Induction and Maintenance of /NKT Cell Anergy
- Urokinase-type Plasminogen Activator Induces BV-2 Microglial Migration through Activation of Matrix Metalloproteinase-9
- Effect of Alcohol Consumption in the Obese Mouse Immune System
- LPS Mediates ROS in NFATcl-induced Osteoclast Formation
- Immune Modulation Effect of Acanthopanax divaricatus var. albeofructus
- Effect of Ephedrine Consumption in the Obese Mouse Immune System
- Integrin α3 siRNA Confers the Proliferative and Anti-Migratory Activity of Human Lung Cancer Cells
- Novel Chalcone JSH 4-4 Inhibits IkB Kinase Beta Down-Regulating Lipopolysaccharide-induced Transcription of Inflammatory Genes in IVlacrophages
- Immunomodulatory Effects of the Fermented Extracts from Medicinal Herbs and Its Activities on Skin Disorder
- Immunomodulatory Effects of Ginsenoside Rpl, a Ginsenoside Derivative, on Macrophage-mediated Inflammatory Responses
- Molecular Delineation of γ-Ray-Induced NF-kB Activation and Pro-Inflammatory Genes in SMP30 KO Mice
- Characterization of Novel W nt/beta-catenin Pathway Inhibitor
- Molecular Analysis of Hypoxia-induced Genes in Early Ocular Vessel Development
- Molecular Mechanism of Histone Deacetylase Inhibitor (HDACI) Apicidin-lnduced Differentiation in Embryonic Carcinoma Cells
- The Biphasic Effect of PD98059 : Crosstalk Between Wnt and ERK Signaling
- Cellular Toxicity of Siiica and Zinc Oxide Nanoparticles in Human Alveolar Epithelial Cells
- Regulation of Differentiation by Aloin in Chondrogenesis Cell-line ATDC5
- Discovery of Multidrug Resistant Reversal Agents through Image Based High Throughput Screen
- Fluorated Bispyridinium Oximes as Improved Reactivators Against Organophosphorus Toxic Agents
- Celecoxib Inhibits Hypoxia-Induced HIF-1 Activation in Rat Cardiac H9C2 Cells
- Synthesis and Antifungal Activity of Substituted 1H-pyrrolo 4,9-dione
- Concise Synthesis of Stilbene Derivatives as Potent Protein Tyrosine Phosphatase IB Inhibitors
- Design, Synthesis and Evaluation of 2-Phenyl-lHbenzo[d]imidazole-4,7-diones as Vascular Smooth Muscle Cell Proliferation Inhibitors
- Pharmaceutical Formulation and Evalution of Hot Melt Granulated Matrix ( HIMGM ) Tablets Using Lipophilic Release Controller
- Risk Assessment of Drug Adverse Events and Establishment of Safety Information System
- Step Up Therapy for Ulcerative Colitis, But Step Down Therapy for the Prevention of Colitic Cancer
- Function of DJ -1,a Causative Gene Product for Familial Parkinson's Disease, and its Therapeutic Application to Parkinson's Disease
- Considerations for Special Characteristics of Cell Therapy Products as Drug
- Naturally Occurring Anti-inflammatory and Antioxid ative Substances with Cancer Chemopreventive Potential
- Drug Metabolism / Transport and Drug Interaction : Regulatory Perspectives of KFDA
- Vitamin E, Mechanisms of Transport and Genetic Disorder
- Drug Development for Hyperlipidemia using an Herbal Formula , SGMX
- Intracellular Delivery of the Cytoplasm ic Domain of CTLA -4
- Relationship Between the Nrf2-antioxidant System and Chemoresistance to Doxorubicin in Human Ovarian Cancer A2780 Cells
- Genetic Toxicity Test of Methyl Methanesulfonate by Ames, Micronucleus, Comet Assays and Microarray Analysis
- Induction of B Cell-selective Apoptosis by Shizukaol B
- lnterleukin- 6 Is a Potent Mitogen In Ovarian Cancer Cells
- Asymmetric Synthesis of D-Ribo-Phytosphingosine
- Effects of Prednisolone on the Pharmacokinetics of Loratadine after Oral and Intravenous Administration of Loratadine in Rats
- Fustin Attenuates Cognitive Dysfunction Induced by β-Amyloid in Mice
- Total Synthesis of Bioactive Macrocyclic Alkaloids:New Entry to Functionalized Macrolactams
- Inhibitory Effect of HY-01 on Neointimal in Rat
- Differential Roles of NF-kappaB and MAPK Signalings in Dendritic Cell Maturation
- Preparation of Self Nanoemulsifying Drug Delivery System of Coenzyme Q IO
- Development of Molecular Imaging of Redox Status in Oxidative Disease Models
- Induction of Autophagy by the Synthetic Bile Acid Derivative, HS-1200, in Hepatoma Cells
- Patent Issues on Biological Products-Patent Map about Therapeutic Antibodies
- Quantitative Determination of Spicatoside A Using HPLC-CAD and Optimized Pressurized Liquid Extraction of Spicatoside A from Liriopeplatyphylla
- Improved Stability by The Formulation Change of Tumor Necrosis Factor-Related Apoptosis Ligand ( TRAIL )
- New Insights into JNKl Function in UV-induced Apoptosis and Prevention of Skin Carcinogenesis.
- Growth Inhibition and Induction of Cell Cycle Arrest Mediated by Coptisine in Human Lung Cancer Cells
- Mutant Presenilin 2(N14II) Increases Beta-secretase Activity through Increase of ERK Pathway Dependent Hydrogen Peroxide
- Recent Issues of Endocrine Disruptors in Medicine and Cosmetics
- Regulatory Involvement of the Transcription Factor Nrf2 in the Murine MDM2 Expression
- Anti-Inflammatory Mechanisms of Resveratrol in Activated HMC-1 Cells: Pivotal Roles of NF-kB and MAPK
- Tamoxifen-mediated Clusterin Suppression through Ubiquitin-proteasome Pathway in PC-3 Human Prostate Cancer Cells
- Quantitative Analysis of Toxic Components from Aconiti Lateralis Radix Preparata by HPLC
- Simultaneous Determination of Bioactive Saiko-saponins in Bupleuri Radix by High Performance Liquid Chromatography with Evaporative Light Scattering Detector
- Chemical Genomic Approach to Drug Repositioning
- Application of GPCR Panel Screening System into Drug Repositioning
- Metabolomics : Application to Prediction Adverse Effects by NSAIDs in Rat Urine
- Hepatoprotective Effects of Adenine Nucleotide Translocator-2 against Oxidative Stress and Aging
- Chemistry and B iology of Alph-Galactosyl Ceramide Homologues
- Inhibitory Effects of Aptosimon Isolated from the Daphne genkwa on the Inflammation Mediators , iNOS and COX -2 Expression in RAW 264 .7 Cells
- Comparative Dissolution of Alfuzosin
- Formulation and Evaluation of Lacidipine Using the Solid Dispersion System
- Therapeutic Effect of PEGylated TRAIL /Hyalu-ronic Acid Nanocomplexes on Rheumatoid Arthritis
- Pharmacokinetics of Phenolsulfonphthalein , a Model Substrate of Multidrug Resistance-associated Protein 2 , with Pretreatment of Quercetin
- Development of Fast Dissolving Tablet Containing Oriental Medicine by Freeze-Drying Technique
- Recent Advances in Computational Methods for Drug Discovery
- Development of Herbal Hepatotherapeutics Using an Herbal Formula, CGX
- Overview of the Validation
- Regulatory Perspectives on Biosimilars : Quality Issues
- Comparative Pharmacokinetic Evaluation of Controlled-and Immediate-Release Tablets Containing Simvastatin
- Regulations and Evaluation on Functional Cosmetics
- Exposure Levels of Endocrine Disrupting Phenolsin Breast Milk-Feeding Mothers and Their New Born Babies
- Digital TMA : The Database of Comprehensive Clinicopathological Data and Digital Tissue Images on Human Cancer Specimens
- Neuroprotective Lignans from Biota orientalis Leaves
- Bioactive Constituents from the Leaves of Zanthoxylum schinifolium
- Separation and Identification of Phlorotannins from the Ecklonia stolonifera by Reversedphase HPLC
- Reduced Antidiabetic Effect of Metformin in Rats with Ethynylestadiol-lnduced Cholestasis via Down-Regula-tion of Hepatic Octl
- Effect of Food Fat Content on the Itraconazole Pharmacokinetics in Healthy Volunteers
- Pharmacokinetic Studies of Ginsenoside Rg₁in Rats
- Identification of the Integrin Binding Domain in TIMP-2 :Potential Novel Peptide Therapeutic in Cancer Treatment
- Practical Use and Drug Development for Alzheimer's Disease from Multi-herbal Drug Combinations (LMK02)
- Puerarin Protects against Oxidative Stress-Induced Cell Death through the Estrogen Receptor Dependent PI3K/Akt/HO-l Pathway
- Standardization of Information on Drug Approval and Strategies to Support Development of Medicine
- IkB Kinase a (IKKα) is Involved in Nuclear Regulation of Histone H3 in the Transient Focal Cerebral Ischemia of Mice
- Saponins Derived from Roots of Platycodon grandiflorum Inhibits Ig-E-Induced Mast Cell Activation
- Anti Allergy-inflammatory Effects in the Korean Herbal Medicine "Juk-yo', from Inner Layer of Bamboo (Phyllostachys nigra), in Splenocytes, Bone Marrow Mast Cells and Asthma Murine Model
- Differential Proteome Expression of Invasive and Non-invasive Human Breast Epithelial Cells.
- New Quinolizidine Alkaloids from Lagerstroemia indica L .
- Salmon Calcitonin (sCT ) Delivery through Buccal Mucosa with Chemical Enhancers and Iontophoresis
- Phytochemical Constituents of the Ethanol Extract from Galla Rhois and Their Anti-inflammatory Effects on LPS Induced Nitric Oxide in RAW 264 .7 Macrophages
- Therapeutic Effects of Hydrogel Preparations Containing Houttuynia cordata and Hydrolyzed Products of Onionon Dermatitis and Wounds
- Gene Silencing with siRNA Targeting HMGAl Inhibits Growth of Tumor Cells in vitro
- Study on Polymorphism of Atorvastatin
- In vivo siRNA Delivery via EDOPC-based Cationic Liposomes
- Pharmacogenomic Haplotype Analysis of the Korean Population and Ethnic Comparisons
- Role of Kupffer Cells in Vascular Stress Genes during Trauma and Sepsis
- Establishment of Testing Approaches for Assessing Safety for NanoBio Products
- Comparisions of HPLC Patterns of Wood Vineger (WV), Bamboo Caulis in Liquamen (BCL) and Korean Red Pine Wood Vineger (WVK) Using Three Common Characteristic Compounds
- Determination of the Related Compounds in Metformin Hydrochloride and Bambuterol Hydrochloride
- Development of Lung Cancer Targeting Hemato-porphyrin-Modified Nanoparticles
- Formulation and Characterization of Alendronate loaded Nano /microparticles for the Enhanced Oral Absorption
- Transdermal Delivery of Ceramide Using Sodium Deoxychloate-based Deformable Liposomes
- Expressional Changes of Transporters in Folic Acid Induced Acute Renal Failure and Their Effects on the Pharmacokinetics and Renal Secretory Processes of Belotecan
- Drug Developement for Asthma using Inula Flos or Mixed Hebal Medicine Materials containing Inula Flos
- Molecular Weight-Dependent Biliary Excretion Of Quartemary Ammonium Compounds
- Cardiovascular Safety Evaluation of Antidiabetic Drugs
- Technical Assistance in Medical Product Development and Regulatory Sciences
- The Anti-Oxidative Effects of Quercetin-3-O-β-Dglucuronopyranoside (QGC) on Interleukin-1 Beta-induced ROS Production in Feline Esophageal Epithelial Cells
- Development of a Novel CBl Receptor Antagonist as an Anti-diabetic Agent
- Regulatory Perspectives on Biosimilars :Non-Clinical / Clinical Issues
- Cellular Adaptive Survival Response to Oxidative , Nitrosative and Inflammatory Stress
- Production and Quality Control of Cell /Gene Therapy Product Tissue Gene-C ™
- Inhibitory Effect of Rutin on Intracellular Calcium, Histamine Release and β-hexosaminidase Activity in RBL-2H3 Cells
- Malondialdehyde Changes of Plasma and Tissues by N-nitrosodiethylamine-induced Oxidative Stress of Lutein-fed Mice
- Mollugin and Its Synthetic Derivatives Inhibit TNF-α-induced Intestinal Inflammation via Suppression of Inflammatory Mediators in HT-29 Human Colon Epithelial Cells
- Novel Chalcone JSH-1144 Inhibits Interleukin-3-induced JAK/STAT Signaling in pro-B BaF/B03 Cells
- Six New Diterpene Glycosides from Pharbitis nil CHOISY
- Alternative Method Development of Hazardous Reagents Using Method in Korean Pharmaceutical Codex
- Synthesis of 3,8-Dihydroxyquinolin Derivatives and Their Antibacterial Activity on Resistant Bacteria
- Neurite Outgrowth Promoting Effect of CBio2008 via Induction of Brain-Derived Neurotrophic Factor through Activation of the ERK Signaling
- Both Fractions of Ethylacetate and Methylene Chloride Extracted from Bokboonja (Rubus coreanum ) Wine Causes Vascular Relaxation
- A Novel Cardiovascular Protective Agent from Plant Resources:Balance between ROS and NO
- Antioxidant Plant Constituents
- Centralized DUR and Prescription Management : Leveraging the U.S. Experience in other Countries
- Anti-Inflammatory and Related Activities of the Ethanol Extract of Salvia plebeia R. Brown
- Measurement of Anti-Cancer Activity Induced by Anti-human CD24 Monoclonal Antibody for Ovarian Carcinoma Cells
- Characterization of Vitellogenin Cloned from Slender Bitterling and Its Regulation by EE2
- Ginsenoside Rg3 Induces Apoptosis of Human Breast Cancer MDA-M B-231 Cells.
- 3D-QSAR Study of 3,8-Diazabicyclo[4.2.0]octanes as Nicotinic Acetylcholine Receptor Agonists
- Release-modulating Mechanism of Disintegrants from PEO Matrix Tablet
- Formation Mechanism of Self Nanoemulsion from Sutface-adsorbed Solid Dispersion Containing Water In soluble Drug
- Overview on Vaccine Production Technologies and GMP-Based Production
- Intranasal Immunization with Recombinant Toxin Co-regulated Pilus and Cholera Toxin B Subunit Protects Rabbits against Vibrio cholerae O l Challenge
- Structure-activity Relationships of Truncated 4'-Thioadenosine Derivatives as Potent and Selective A₃Adenosine Receptor Antagonists
- Population and Heat Shock Genes Expression of the T cells in Transgenic Mouse Expressing Small Ubiquitinlike Modifier 2
- JNK1 and JNK2 as Potential Targets for Chemoprevention of Skin Carcinogenesis
- Development of New Reporter Gene Assay System Using AhR-Related Genes Cloned from Goldfish
- Ceramide 1-Phosphate, a Novel Bioactive Sphingolipid, Has an Important Role on Neointimal Hyperplasia after Rat Carotid Artery Injury
- LPA2 and Gi/Src Pathway Mediate Cell Motility through COX-2 Expression in CAOV-3 Ovarian Cancer Cells
- Development a Method for Quantitative Determination of Pioglitazone in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry
- Change of Mineral Concentrations in Backbone of Mice for 3 Months by Oral Intake of Boron and Calcium
- Chemical Genetic Approach to Ubiquitin-Proteasome Biology:A Novel Strategy for Chemoprevention and Chemotherapy
- Gene Expression Profiles of Chlorambucil by Microarray Analysis and Genetic Toxicity Test
- Lactic Acid Bacteria Increase Anti-prurutic Effect of Ixeris sonchifolia
- Effect of Collagen-PHBV (PHCP) Nanoflber to H2O2-Mediated Apotosis and Wound-Healing Mouse Model
- Inhibitory Effect of the Compounds Isolated from Rhus verniciflua on Aldose Reductase and Advanced Glycation Endproducts
- Anti-inflammatory Activity of Synthetic C-O-C Biflavonoids
- Structural Insight into Toxin-Antitoxin System of Helicobacter pylori
- A Combined Chemoimmunotherapy Approach Using a Plasmid-Doxorubicin Complex
- Human Papillom a Virus E6 /E7 siRNA Potentiates Therapeutic Effect of Cisplatin in Cervical Squamous Cell Carcinoma
- Application of NMR-Based Urinary Metabolomic Profiling in Hepatoxicity-lnduced Rats
- The Study of the Ionic Interaction on the Substituted Derivatives with pK. Values
- An EfTicient Synthesis and Purification of Pharmaceutically Available Hydrochlorothiazide, 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiazide-7-sulfonamide- 1,1-dioxide
- A New HPLC Method for the Simultaneous Determination of Phenylephrine Hydrochloride , Guaifenesin ,Chlorpheniramine Maleate and Dextromethorphan Hydro- bromide in Cough Syrup
- Antioxidative Constituents from Euphorbia supina
- The New Condensed Tannins from the Roots of Rosa multiflora Thunberg
- Economical Evaluation for Unification of Medical Terminology in Different Hospitals
- Development and Validation of a Simple, Fast and Sensitive LC-MS /MS Method for Quantifying Doxifluridine in Beagle Dogs
- Assessment of Dosage Based on Renal Dosing Criteria
- Evaluation of Multiplex Genotyping Method for the Nanogen NanoChip 400 System
- Anti-obesity Effect of Sesam um indicum Leaf Extract in the ICR Mice
- The Cytotoxic Effect of Capsaicin is Mediated by Increased Oxidative Stress in Neural Progenitor Cells
- Development of a Novel Factor Xa Inhibitor Synthesized from the Earthworm and its Potential Effect through Cell Surface Receptor, Proteinase-activated Receptor
- Suppression of Atopic Dermatitis Like Skin Lesions in NC/Nga Mice by Molecule Isolated from Lactobacillus casei Cell-free Supernatant
- Novel Synthesis of Substituted Aminocyclitols as New Glycosidase Inhibitors
- Synthesis and Biological Activity of Novel 5-lodoneplanocin A and Its Analogues
- Design, Synthesis and Conformational Analysis of Novel 2',3'-Didehydo-2',3'-dideoxy-4'-selenonucleosides
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