두경부 말초신경초종의 임상적 고찰

• 영문명: A Clinical Analysis of Peripheral Nerve Sheath Tumors in the Head and Neck Region
• 발행기관: 대한두경부종양학회
• 저자명: 강석영(Seok Young Kang) 신명철(Myung Chul Shin) 유한석(Han Seok Yoo) 이용섭(Yong Seop Lee) 박철원(Chul Won Park) 태 경(Kyung Tae)
• 간행물 정보: 『대한두경부종양학회지』제24권 제2호, 174~178쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2008.11.30

영문 초록

Background and Objectives ：Peripheral nerve sheath tumors(PNSTs) are uncommon neoplasm in the head and neck region. The treatment of PNSTs is surgical removal, but excision cause neurologic complications. This study was performed to evaluate the proper diagnosis and treatment of PNSTs with our experiences. Subjects and Method ：During the period from October 1994 to July 2007, 58 patients were diagonised with PNSTs in head and neck region. We reviewed medical records and imaging study retrospectively. Result ：95%(55/58) of the PNSTs in head and neck were benign；5%(3/58) were malignant peripheral nerve sheath tumors(MPNSTs). 63%(37/58) were neurilemoma, 20%(17/20) were neurofibroma, 2%(1/58) was perineuroma. 55 patients underwent surgery. 80%(45/55) of cases were treated with excision. Enucle-ation was performed in 7(14%) patients. All cases of benign neurogenic tumors showed no recurrence. Among 3 of MPNSTs 2 patients were Von Recklinghausen’s disease and expired with regional recurrence and lung metastasis. Conclusion ：The benign PNSTs can be treated with enucleation if possible and observation can be another choice to minimize neurologic sequele.

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키워드

Neurilemoma Neurofibroma Peripheral nerve sheath tumor 신경초증 신경섬유종 말초신경종양.