비인강암의 동시 항암화학방사선치료

• 영문명: Concurrent Chemoradiotherapy in Nasopharyngeal Carcinoma
• 발행기관: 대한두경부종양학회
• 저자명: 정은지(Eun Ji Chung) 김용태(Yong Tai Kim) 홍현준(Hyun Jun Hong) 홍원표(Won Pyo Hong)
• 간행물 정보: 『대한두경부종양학회지』제24권 제2호, 169~173쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2008.11.30

영문 초록

Purpose ：This is a retrospective study to evaluate the results of concurrent chemoradiotherapy in nasoph-aryngeal carcinoma. Material and Methods ：From Mar 2000 to June 2005, 18 patients with nasopharyngeal carcinoma completed planned concurrent chemoradiotherapy. Stages were I in 1 patients, II in 2 patients, III in 7 patients and IV in 8 patients. Pathologic type was squamous cell carcinoma(WHO type 1) in 2 patients, non-keratinizing type(WHO type 2) in 8 patients and undifferetiated carcinoma(WHO type 3) in 8 patients. The follow up period ranged from 30 months to 95 months with a median of 56 months. Follow up was possible in all patients. Results ：Response to concurrent chemoradiation therapy was a complete response in all patients. Patterns of failure were as follows：local recurrence in only one patient(5.6%) and distant metastases in three patients with N3 diseases(16.7%). The overall 5 year survival rates were 88.5%, the 5 year disease free survival rate was 77% and these were very good results. There were no significant differences in the local control and survival rates between the clinical stages and pathologic types. Conclusion ：The outcome of the nasopharyngeal carcinoma treated with concurrent chemoradiotherapy was very good, even though most of the patients(15/18=83.3%) were in stage III and IV diseases. We concluded that concurrrent chemoradiotherapy in nasopharyngeal carcinoma showed the good local control and survival rates without significant complications. In the patients with N3 disease, we have to consider the more effective and strong chemotherapeutic regimens to prevent distant metastases.

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Nasopharyngeal cancer Concurrent chemoradiotherapy 비인강암 동시 항암화학 방사선치료.