동충하초에서 분리된 신규 항암물질의 효율적 합성법 개발

• 영문명: Development of an Efficient Synthetic Method for a Novel Anticancer Substance Isolated from Insect-flower
• 발행기관: 대한약학회
• 저자명: 차해연(Haiyan Che) 트루옹 넉 투엔(Ngoc Tuyen Truong) 윤덕효(Deok Hyo Yoon) 김태웅(Tae Woong Kim) 성기호(Gi-Ho Sung) 박해일(Haeil Park)
• 간행물 정보: 『약학회지』제56권 제2호 (2012년), 71~73쪽, 전체 3쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.04.30

영문 초록

Cordyceps militaris, a caterpillar-grown traditional medicinal mushroom, produces important bioactive compounds, cordycepin (3'-deoxyadenosine) and militarin. Militarin is reported to possess anticancer activities against several tumor cells. An efficient synthetic method of militarin was developed to prepare muti-gram scale sample for bioassay. Militarin was successfully synthesized from commercial starting materials in 5 steps and 29.3% overall yields.

키워드

Cordyceps militaris militarin anticancer activity multi-gram scale