학술논문
In vivo antitumor activity of Hyrubicin ID6105 : Targeted inhibition of heme oxygenase in solid tumor
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- KWON Koo-Hyun LEE Pung Sok LEE Jung YeoI HAN Jin-Yi HONG Jin-Tae SONG Sukgil CHUNG Youn- Bok RYU Jung-Su KIM Tae-Yong LEE Hong-Sub
- 간행물 정보
- 『추계총회 및 학술대회』(2006년) vol.2, 322~323쪽, 전체 2쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2006.11.30
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- Antioxidative, whitening and anti-wrinkle effects of Vaccinium uliginosum extracts
- Role of Copper Transporters in Cisplatin Resistance
- Cytotoxic constituents from Aralia cordata
- On-chip Monitoring of Drug-induced Cell Viability Mediated by Apoptosis Using Biochip
- Anti-Angiogenic, Anti-Inflammatory and Anti-Nociceptive Activities of Vanillin
- Release of Sphingosine-l-Phosphate from Platelets that isIncreased by Enhancement of Platelet Sensitivity in Hypercholesterolemia : Roll of Sphingosine -l-Phospate on the Development of Atherosclerosis
- The signaling mechanism of lysophosphatidic acid-induced COX-2 expression in cultured feline esophageal epithelial cells.
- Characterization of Chemically Depolymerized Acharan Sulfate and Chondroitin Sulfate by Free Radicals Induced by Hydrogen Peroxide with Copper Salts
- o ,p-DDT Increases the Expression and Activation of Matrix Metalloproteinase- 2 in Human Fibrosarcoma HT1080 Cells
- Quercetin activates an angiogenic pathway HIF-l-VEGF by inhibiting HIF-prolyl hydroxylase: A structural analysis of quercetin for inhibition of HIF-prolyl hydroxylase
- Regulation of Matrix Metalloproteinases (MMPs ) by ErbB 2 in MCFIOA Human Breast Epithelial Cells
- Evaluation of Anti-hepatic Cirrhosis Effects by Rutaecarpine on TAA-induced Hepatic Cirrhosis in Vitro and in Vivo
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- Characterization of the transport of berberine across Caco-2 cell monolayers
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- Genotoxic effects and lung cancer-related gene expression by urban air-borne particulate matters (PM2.5)
- The adaptive surv ival response against oxidat ive stress due to iron overload in bthalassemia / HbE (b-Tha l/HbE ) patients
- T-bet, a Master Regulator of T hl Cell Differentiation
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- A metabolomic approach to evaluate toxicological effects of bisphenol A and nonylphenol on rats
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- Distribution of Lidocaine and Bupivacaine in Patient after Epidural and Spinal Anesthesia.
- Protective Effects of Viticis Fructus Extract against Acute Liver Injury induced by Acetaminophen in Mice
- Induction of Heme Oxygenase-1 Expression by the Anthocyanin Extracted from Purple-Fleshed Sweet Potato
- Determination of Carbamazepine in Human Plasma using HPLC
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- Effect of gamma-irradiated ovalbum in (OVA ) on OVA -induced allergy in mice
- Evaluation of Genotoxicity in Endometrial Cancer Induced by Tamoxifen
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- Pharmacokinetics of Paclitaxel of New Micelle Formulation
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- 2',4',6' -T ris(methoxymethoxy) Chalcone Attenuates Hepatic Stellate Ceil Proliferation by a Heme Oxygenase-Dependent Pathway
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- Review of Drug Interaction based on Outpatient's Prescriptions published in General Hospital
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- Identification of the enzymes in vitro involved in metabolism of l-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound
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- Genotoxicity Tests for the Prediction of Carcinogenecity.
- Enhanced the oral bio availability of etoposide by concomitant administration of quercetin in rats
- Determination of Metformin in human plasma by Liquid chromatography-Tandem Mass Spectrometry
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- Effects of Morphine Exposure on Glutamate Uptake in the Cultured Cerebellar Astrocytes
- The Effects of VKORCl Polymorphims on the Pharmacokinetics of Menatetrenone and Its Major Metabolite.
- High-throughput Dniggability Evaluation in Korea Chemical Bank
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- Determination of plasma concentrations of losartan in healthy volunteers by high performance liquid chromatography with fluorescence detection
- Validation of a high-performance liquid chromatography method for the determination of assay and purity of sibutramine hydrogensulfate
- Arsenite enhances procoagulant activity by phosphatidylserine exposure and microparticle generation in human platelets
- Immunological Adjuvanticity of 18 p -G lycyrrhetinic Acid Induces Protective Antibody against Disseminated Candidiasis in M ice .
- The Effects of Lactobacillus Rhamnosus LCR35 on the Methotrexate and Starvation Induced Bacterial Translocation
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- The Effect of Oxidative Stress and Calcium Ion on Taurine Transport through the Blood -Placental Barrier
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- Gene expression profiling of dedifferenatiated murine myoblast reveals correlation between epigenetics and lineage specificity .
- Molecular Mechanism of Apicidin-Induced Down-regulation of DNA Methyltransferase 1 Expression
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- Determination of Tolterodine in human plasma by Liquid chromatography-Electrospray Ionization Tandem Mass Spectrometry
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- Non-epimerizable Isosteric Analogs for the Putative Metabolites of Thalidomide
- Inflammation as the Link between Normal Aging and Disease
- Cytotoxic Effects of the Essential Oil Fraction and Its Main Components of Ligusticum Chuanxiong on Various Cancer Cells
- Production and Characterization of Low Molecular Weight Heparins by Recombinant Heparinase I
- Issues and Prospects of Drug Sector Negotiation in KORUS FTA
- An Adjuvant Effect of a Combination of E. coli DNA Fragments and Modified L ipopolysacchar ides to HBV Vaccine
- Inflexinol, a NF-kB inhibitor prevents colon cancer cell growth via induction of apoptotic cell death
- Synthesis and biological evaluation of 5-arylamino-6-chloro-lH-indazole-4,7-diones as inhibitors of protein kinase B/Akt
- Novel Pharmacological Activities of Gallic Acid.
- Leonurus sibiricus induces nitric oxide and tumor necrosis factor-alpha in mouse peritoneal macrophages
- Davallialactone, isolated from Inonotus xeranticus, is apotent anti-inflammatory priciple with inhibiting Akt/PI3K pathway
- The Issue of FT A between the U.S. and the Korea in the Pharmaceutical Industry
- The role of Rho-kinase inhibition in isoflavonoids-induced vasorelaxation.
- Recent Trends and Evaluation on DNA Chips
- Novel Formulations Safely Improving Absorption of Poorly Absorbable Drugs
- I nvolvement of COX -2 in TRANCE -induced Osteoclast Formation by PDE4 inhibitor
- In vitro Antiinflammatory Activity of Hibiscus manihot in Murine Macrophage Raw 264.7 Cells
- The effects of hair washing and coloring on concentrations of methamphetamine and amphetamine in hair
- Long-term Measurement of Physiological Cardiovascular Parameters using Telemetry system in Monkey
- The effect of Allan thus altissima swingle on mast cell-mediated inflammatory response.
- Molecular Modeling of Acetylcholinesterase and the newly synthesized AChE Inhibitors comparative Donepezil
- Inhibitory Action of Arctigenin from Arctium Fructus on DNFB- and PC-induced Contact Dermatitis
- Single Oral Dose Toxicity Test of Water Extracts of Puerariae Radix in ICR Mice
- Inhibitory effects in melanin synthesis and tyrosinase activity, cytotoxicity in Melanoma cell B16B16 and antioxidant, antibiotic activity by Thymus magnus extracs .
- Farnesyl Protein Transferase Inhibitory Compounds from Lithospermum erythrorhizon
- Effects on and Policy Implications for Drug Expenditure Issues in KORUSFTA
- Epothilone inhibits neointimal hyperplasia by inducing arterial smooth muscle cell apoptosis via p53-dependent caspase-3 activation
- Molecular Basis for the Cardioprotective Effect of BMS-180448 in a Rat Heart Model of Ischemia and Reperfusion (I/R) Injury
- Ethanolic Exteracts of Brassica rapa L. Prevent High-Fat Diet Induced Hyperlipidemia and Obesity in ICR Mice
- Effect of Silibinin on Experimental Autoimmune Encephalomyelitis
- Effects of HDAC inhibitors on Huntingtin Aggregation and Huntington's Disease Model
- Effects of Chrysanthemum morifolium Extracton The Synthesis of Basement Membrane Proteins of Calf Pulmonary Artery Endothelial Cells
- Curcum in differentially modulates LPS- activated signaling pathways in macrophage
- Transition Ratio of Cytotoxic Alkaloid Components and Toxicity in Herbal Prescriptions Containing Aconitum Species.
- Toxicogenomic Analysis of Acute Ethanol Exposure in Mouse Liver : Global Gene Expression Changes and Lipid Metabolism
- A Facile Synthesis of Trisaccharide Template Corresponding to Antitumor Activity in Triterpenoid Saponins Isolated from Pullsatilla koreana N.
- Angiotensin-converting enzyme I inhibitory activity of phlorotannins from Ecklonia stolonifera
- Phytochemical Constituents of Saussurea triangulata
- Validation of a HPLC MS/MS Method for Determination of Doxorubicin in Mouse Serum and its Small Tissues.
- Activation of MAP kinase Isoforms in Cortical Neuronal Cell Death Induced by Oxygen-Glucose Deprivation
- The Synthesis and Biological Evaluation of a Novel Series of Antibacterial of the Oxazolidinone Formamide Derivatives
- Pinl Pins down JN Kl to Enhance JN Kl Activity
- Postmortem heart blood and femoral vein redistribution of many kinds of drugs
- CCRS -mediated promotion of neurogenesis of neuronal stem cells and functiona centra nerve system development
- The activation of NF-kB through Akt-induced FOXOl phosphorylation during aging and its modulation by calorie restriction
- Antioxidative and Anti-inflammatory Activity of Sopungsan's Prescription.
- Anticonvulsant Effect of Baicalein Isolated from Scutellaria baicalensis
- Antimicrobial Activity of Mupirocin, Daptomycin, Linezolid,Quinupristin /Dalfopristin and Tigecycline against Vancomycin -Resistant Enterococci (VRE ) from Clinical Isolates in Korea (1998 and 2005 )
- Lead enhanced procoagulant activity mediated through phosphatidylserine exposure in human erythrocytes: A contributing factor to cardiovascular disease
- Antiparkinsonian Effects of Dextromethorphan Analogs
- Development of Ibuprofen-loaded Coated Gelatin Microcapsule as a Long Acting Oral Delivery with Bioavailability Enhancement
- Abnormal Accumulation of Citrullinated Proteins by Peptidylarginine Deiminase 2 (PAD2) in the Mouse Modelof Prion Disease
- 7,7^-dihydroxy bursehernin inhibits the expression of inducible nitric oxide synthase through NF-kB DNA binding suppressio
- p53 dependent apoptotic cell death by berberine in human neuroblastoma and prostate cancer
- The effect of racemates and enantiomers of higenamine and its analogs, YS-49 and YS-51, on platelet glycoprotein expression.
- Neuroprotective effects of apigenin through inhibition of microglia cell activation
- Differential effects of apicidin, a histone deaceylase inhibitor, on regulation of apoptosis through the ERK pathway in H-ras-transformed human breast cancer cells
- Inhibitory effect of water fraction from Bupleuri Radix on SP ligand binding in neurokinin-1 receptor using U-373MG cell-based assay system
- Synthesis of Benzoxazole Containing Indole Analogs and Their Inhibitory Activity on p-Amyloid Aggregation
- The antioxidant effect of lipoic acid on B16F10 murine melanoma cell
- Effects on and Policy Implications for Intellectual Property Right (IPR) of Drugs in KORUS FTA
- The Combination Effects of Interferon-alpha and Artemisinin on Differentiation of Human Promyelocytic Leukemia HL-60 Cells.
- Role of Nur77 in oxidative stress - induced cell death
- Luteolin Induced Growth Inhibition in Hepatoma Cells Involving TGF -p , Fas/Fasligand, and p53 Signaling Pathways
- Molecular mechanisms of hydroquinone-mediated inhibition of macrophage responses
- The Constituents of 19a-Hydroxyursane-type Triterpenoid from the Leaves of Rubus crataegifolius
- The Study on the Unification of Theories of the Oriental Medicine-Sihnsanghanron(New Sanghanron)-
- Rapid determination of Phenylbutazone and Oxyphenbutazone in equine plasma by GC/MS
- Anti-diabetic activity of IH-901 in db/db mice
- Vinegar processed ginseng radix prevents Diabetes and hyperlipidemia in db/db mice
- Determination of calcitriol in human plasma with validated and quantitative analysis of enzyme-immunoassay for bio availability study
- Practical Approach to Qualification of GMP Facility
- Anxiolytic-like effects of Zizyphi Spinosi Semen: Possible involvement of the GABA/benzodiazepine receptor complex
- Anti-diabetic effect of the major active components isolated from Salvia miltiorrhiza Bunge by an analysis of the effet on insulin receptor signaling
- Primary tumor regression and anti-metastatic efficacy of Genexol？？-PM, a polymeric micellar paclitaxel formulation, in a green fluorescent protein orthotopic model of pancreatic cancer
- Activation of p38 MAPK Induced Peroxynitrite Generation in LPS plus IFN -y -Stimulated Rat Pr imary Astrocytes via Activation of iNOS and NADPH Oxidase
- Effects of Bisphenol A and Nonylphenol on Cytochrome P450 Enzyme Activity in Rats
- An Analysis on the Factors affecting Revisit and Defection of Long-term outpatients in Neighboring Pharmacy of General Hospital
- Evaluation of Combined Vaccines
- Effects of Delta Frequency Magnetic Field on the Chemiluminescence of Mouse Brain
- Anti-inflammatory Activity of Fisetin in Human Mast Cells (HMC-1)
- Enhancement of insulin secretion by IH-901, an intestinal metabolite of ginseng saponin in HIT-T15 and primary cultured rat pancreatic islets
- A study of need for medication education and care management for elderly patients in an aging society
- Phytochemical Constituents of Synurus excelsus
- Design and Synthesis of N-Aryl-6-hydroxy-7-methoxy-2-chromancarboxamide Derivatives as Potential Anti-inflammatory Agents.
- A New Analytic Method for Quantification of Urinary 1-Hydroxypyrene with internal standard , 9 -Hydroxypyrene
- Diary! ether: Synthesis and biological evaluation as antimitotic agents
- Inhibitory effect of Eriobotrya japonica leaves on inflammatory cytokine production from HMC-1 cells
- Inhibitory Effect of Eupatiiin isolated from Artemisia princeps in IgE-induced Hypersensitivity
- Hepatoprotective Effect of Daidzin in Galactosamine/Lipopolysaccharide-Induced Liver Injury
- Two Novel 7,20-Epoxy-ent-kaurene Diterpenoids from Isodon japonicus and Their Inhibition of LPS-induced Nitric Oxide Production in RAW264.7 Cells
- Ion Mapping of the Retinal tissue by TOF-SIMS
- Anti-salinomycin Monoclonal Antibody Production from Cloned Hybridoma Cell.
- Activation of Estrogen Receptor-Mediated Gene Transcription by the Equine Estrogen Metabolite, 4-Methoxyequilenin in Human Breast Cancer Cells
- A novel Shiga Toxin Neutralizer for Treatment of Shiga Toxin-producing E. coli Infections
- Effects of Immunomodulators on the Antigen Presentation Capability of Dendritic Cells
- Antioxidant activity and whitening effects of various berries extracts
- Protective effect of ginsan on carbon tetrachloride-induced hepatotoxicity
- Development of Screening Methods for Steatogenic Hepatotoxicity using Cell-Based Assay Systems
- Studies on TheIsolation and Structure Elucidation of Anti- inflammatory Ef fects Compound from Sparassis Crispa Wulf, ex Fr,
- Proteomic analysis of differentially released proteins between normal plateletsand hypercholesterolemic platelets
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- Ga₁₂-Mediated Transcriptional Activation of MMP-2 in Human Breast Epithelial Cells
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- NO (Nitric Oxide ) production related to pro-inflammatory cytokine secretion in the presence of LPS (lipopolysaccharide ) : The effect of Chitosan Oligosaccharide in RAW 264.7 cells.
- Regulation of the HIF-la stbility by Histone Deacetylases
- Enantiomeric purity test of etodoiacUsing cinchonidine by H-NMR
- The Study of antioxidant in Salviae Miltiorrhizae Radix
- Microarray Analyses of Gene Expression Changes Induced by Ethanol Extract of Astragalus Membranaceus Bunge
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- Transdermal preparations of lidocaine hydrogel by phonoresis
- A Study to Clarify Ethnical Variations in Susceptibility to Statins
- Improved Glucose-Stabilizing Effect of Biotinylated Glucagon-Like Peptide-1 (GLP-1) : Stability, Pharmacokinetic profile and antidiabetic Efficacy in Type-2 diabetic mice.
- Drug evaluation based on Permeability and Solubility
- Expression of antioxidant enzymes in H411E cells infected by retrovirus containing GFP
- Anti-diabetic effect of extracts of natural products
- Anti-prostate activity of Forsythiae fructus Constituent
- Stability and Degradation Products of 3-Bromopyruvate, a Newly Found Anticancer Drug
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- Immunostimulative Effect of Red Ginseng Acidic Polysaccharides on Cellular Immune Responses in Mice
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- The activation of mast cells is suppressed by curcum in through the inhibition of Syk
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- Antinociceptive, antiinflammatory , sedative, prolonged hypnotic and antidepressant effect of essential oil from Thymus magnus .
- Cytotoxic Effect of Aconiti Korean! Radix and Typhonii Rhizoma on Human Hepatocellular Carcinoma Cell Line
- Effect of karmpferol on the pharmacokinetics of tamoxifen and its metabolite, 4-hydroxytamoxifen in rats
- PEGylated TRAIL in Combination with Doxorubicin Exerted Antitumor Effects on Colon Cancer Cell Line HCT-116
- Anti-diabetes effects of Isaria sinclairii by repeated oral treatment in obese mice over a 6-month period
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- Activation of JNK-1 , ERK -1 /2 and p38 is Required for Glial Cell- Derived Neurotrophic Factor (GDNF )-Induced Migration of Hs683 Glioma Cells
- Synthesis of (+)-decursin analogues and their antitumor activities
- Stability of aceclofenac in the presence of its degrading substance, diclofenac in aqueous and solid state
- Enantiomeric Synthesis and Potent Anti-HIV Activity of Rigid LBicyclocarbanucleoside
- Immunostimulatory Effects of Prunella vulgaris
- Effect of Geranti Bio-Ge Yeast, a Dried Yeast Containing Biogermanium , on the Production of Antibodies by B Cell Proliferation
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- Single-dose Pharmacokinetics of Coenzyme QIO in Korean Healthy Volunteers
- Determination of Penciclovir in Human Plasma by High-Performance Liquid Chromatography: Application to Bioequivalence Study of Two Famciclovir Tablets.
- Lornoxicam pharmacokinetics in relation to CYP2C9*3 and CYP2C9*13 allele
- Anti-fibrotic Effects of IN-1130, a Novel Transforming Growth Factor 15 type I Receptor Kinase (ALK5) Inhibitor, in Pulmonary Fibrosis
- Epothilones induce apoptotic cell death of human colon cancer SW620 cells via tubulin polymerization independent activation of NF-kB/IKK signal pathway
- Neuroprotective Effect of Natural Products with Cell Culture System
- Preparation and characterization of cationic Paclitaxel PLGA nanoparticles
- National Compound Repository System
- The Structure Activity Relationship of Phenanthroindolizidine Alkaloids
- 3D-QSAR Study of Tricyclic Phtalimide Derivatives as HIV-1 Intergrase Inhibitors
- Synthesis of Selenazoloaminoindan Derivatives and Study of Dopaminergic Activity
- Regulatory properties of the M2 type pyruvate kinase, a novel bridge between glycolytic process and allergic reactions
- Guideline on Evaluation of Clinical Trials Neuropsychological Drug
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- Identification and Characterization of Antioxidants from Sophora flavescens
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- Growth inhibition and cell cycle arrest of schizandrin in T47D human breast cancer cells
- Immunomodulatory Effects of Cimicifugae Rhizoma Extracts in macrophages
- In vitro inhibiting activities of the essential oil from Pelargonium graveolens against antibiotic-resistant bacteria
- Rexflavone, a Plant Extract from Sophorae Fructus, Exerts Antiplatelet Activity via Inhibition of Intracellular Calcium Mobilization and Protective Activity on H9c2 Cells
- Preclinical Pharmacokinetics of DY-105359, a Potent PPAR Agonist
- The role of histone H3 K4 methylation in globa chromatin maintenance
- DNA Microarray Analysis of the Anti-Cancer Action of Evodiae fructus Ingredients
- Evaluation of Antioxidant Effects of Some Medicinal Plants
- The Investigation of Optimization of Shikonin derivatives in Lithospermum erythrorhizon sieb
- Q&A in the Bridging Study
- Phosphine-Catalyzed AUylic Substitution of Morita-Baylis-HUlman Acetates:Synthesis of N-Protected p-Aminophosphonic Acid Esters
- Characterization of the Desensitization Properties of Five Dopamine Receptor Subtypes and Alternatively Spliced Variants of Dopamine D2 and D4 Receptors
- Induction of cell cycle arrest and apoptosis mediated by honokiol in human gastric cancer cells
- Changes of gene expression profiling in octachlorostyrene treated Caenorhabditis elegans
- TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation
- Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on CycIooxygenase-2 Expression in Human Endothelial-like ECV304 Cells
- Role of The ATF3 in S. Pneumoniae Infection.
- Establishment of cisplatin resistant sublines from A549 non-small cell lung cancer cells.
- Promiscuous relationships of natural thermo TRP ligands
- Synthesis of New 4-hydroxy-2-Oxoquinoline Analogs of Aleurone Layer of Anthocyanin-Pigmeted Rice
- Molecular Mechanisms of p53- and ROS-induced senescence
- Rational Design, Enantiopure Synthesis and Anti-Viral Evaluation of New Iso-D-2',3'-Dideoxy-3'-fluorothianucleoside Analogues as a Bioisostere of Lamivudine
- Amino Acid Signaling to Neurogenesis in the Rat Brain
- Evaluation of PPARy Agonism of DY-105359 in Vitro and in Vivo
- Pharmacological Activities of Propyl Gallate.
- Development of Xanthone Derivatives Based on Constituents from the Root Bark of Cudrania tricuspidata which Shows a Selective Antibacterial Activity Against MRSA
- Therapeutic Effects of Mesenchymal Stem Cells in Animal Ischemic Brain
- Effects of KIOM-79 on hyperglycemia and insulin resistance in type 2 diabetic Goto-Kakizaki rats
- l- Bromopropane Induces Nitric Oxide and Proinflammatory Cytokines in Macrophages via NF -kB , ERK M itogen-activated Protein Kinases
- Significance of PTK /PTP shift in the inflammatory process :Regu ating NF-kB signaling during aging
- Synthesis of fluorinated acyclic and cyclopropyl nucleosides
- Melatonin Reduces Expressions of Chemokine (C-C motif) Ligand Family Genes in LPS-induced PBMC
- An Ellagic Acid Rhamnoside from the Roots of Potentilla discolor with Protein Glycation and Rat Lens Aldose Reductase Inhibitory Activity
- A newly developed antiarrhythmic drug CW-2602, a furocoumarin derivative, is ideal in treating atrial fibrillation
- Hyperglycemic Effect of Ilex cornuta on Streptozotocin-induced Diabetes Rats
- In vitro immune cell regulatory effects of nonsteroidal anti-inflammatory drugs (NSAIDs) at the clinically available doses
- Phospholipase A₂S Inhibitory Activities of Synthetic Biflavonoids
- Anti-tumor effects of Cordyceps militaris in melanoma
- Growth inhibition and induction of apoptosis by honokiol in MDA-MB-231 breast cancer cells
- Calisomerin: A Multifunctional ER Protein with Calcium Storage and Protein Disulfide Isomerase Functions
- Bioactive constituents from the leaves of Zanthoxyhim schinifolium.
- Alpha-TTP, a Cytosolic Protein that Facilitates the Excretion of Vitamin E from hepatocytes
- Anti-inflammatory Principles from Evodia rutaecarpa and Paeonia lactiflora
- Biodistribution of boron in mouse tissues according to iv or ip injection of BPA
- Transcriptional Activation of MMP-2by TGF-pInvolves ATF 2
- In Vitro Cytotoxic Activity of Some Korean Medicinal Plants on Human Cancer Cell Lines; Enhancement in Cytotoxicity by Heat Processing
- Perspectives on the Blood-brain Barrier: Transporters and Regulation
- Molecular pathway -based characteristics of cerv ical adenocarcinoma and squamous cell carcinoma .
- Sulfation of Resveratrol by Recombinant Arylsulfate Sulfotransferase from Eubacterium A-44
- Asymmetric Synthesis of Cyclopropyl-fused 2'-C-methyl-Carbanucleosides as Potential Anti-HCV Agents
- A Simple and Convenient Preparation of Disaccharide Template Corresponding to Antitumor Activity in a-Hederin
- New Phytochemical Components from the Butanol Fraction of Opuntia flcusindica var. saboten
- N-Acetyl-L -Cysteine Reduces Ethanol Toxicity in Rats.
- Inspection of Clinical Trials
- Anti-inflammatory Activities of Two Phenolic Compounds, 4-Hydroxybenzyl Alcohol and 4-Hydroxybenzaldehyde, in Rat Air Pouch Model
- Synthsis of Buteine Derivatives Which Show Inhibiting Production of NO
- Anti-inflammatory Activity of the Synthetic C-C Biflavonoids
- Sensitivity of Streptococcus pneumoniae cIpL mutants to Oxidative Stresses
- A new herbal formula for hair growth promotion in vitro and in vivo models
- Oral administration of LMWH-DOCA derivatives using DMSO formulation in mice and monkeys
- C-N Bond Formation of Pyridazine Halide With Heterocyclic Amines
- Involvement of Nr f2 Signaling in Cytoprotective Effect of Bromocriptine Against Oxidative Stress
- Synthesis and Conformational Study of 2-Trityloxymethyltetrahydrofurans
- Phosphorylation of Histone H3 at Serine 10 Is Indispensable for Neoplastic Cell Transformation
- Relaxation effect of Rosiglitazone on KCl or thromboxaneA2 mimetic induced contraction of rat aortae.
- Development of Natural Drugs against Antibiotics-Resistant Bacteria from Artemisia and Chrysanthemum Species in Korea and Study on Its Active Mechanism (I)
- The Cyclic Sulfate Chemistry of Phytosphingosine in the Synthesis of Sphingolipids
- Role of Hypothalamic Forkhead Transcription Factor FOXOl in the Regulation of Food Intake and Energy Homeostasis
- An antimicrobial substance fr om centipede
- Stereoselective Functionalization of 1'-Position of 4'-ThionucIeosides
- Stereoselective Synthesis of Homo-apioneplanocin A as Potential Inhibitor of Sadenosylhomocysteine Hydrolase
- Inhibitory mechanism of quercetin 3-0-beta -(2 "-galloyI )-glucopyranoside on IL-6 expression in LPS -stimulated macrophages RAW 264 .7
- Synthesis of 3'-Ureidoadenosine Derivatives as Highly Potent Agonists at the Mutant A₃Adenosine Receptor
- In vivo antitumor activity of Hyrubicin ID6105 : Targeted inhibition of heme oxygenase in solid tumor
- KETAMINE DEPRESSES CATECHOLAMINE RELEASE IN THE ISOLATED ADRENAL GLAND
- MAP kinase is associated with immunomodulating activity of Korean Mist letoe lectin B chain
- Comparison of the Antitumor Activities of Angelica gigas Extract and its Major Components in Human Cancer Cell Lines
- Development of HPLC methods for the analysis of evodiame and rutecarpine in Herbal Medicinal Products containing Evodia Fruit.
- Concise Synthesis of Rodgersinol and Determination of the C-10 Absolute Configuration
- Enhanced menadione cytotoxicity in platelets isolated from streptozotocin-induced diabetic rats
- Inhibition of nitric oxide synthase expression in activated microglia and peroxynitrite scavenging activity by Opuntia ficus indica var. saboten.
- Review of Quality, Safety and Efficacy of Monoclonal Antibody products in Korea
- A Study on the Constituents from Ethyl Acetate Fraction of Orostachys japonicus
- Vision and Strategy of Biologies Headquarter
- Safety pharmacology studies on quinolone antibiotics
- Phytochemical Constituents of Paris verticillata
- The Development of a Novel Antidiabetic Agent Lobeglitazone (CKD-501)
- Develpment of Novel Carbocyclic Nucleosides as Potent Antiviral and Antitumor Agents
- Anti-carcinogenic effect of Akebia saponin D from the Roots of Dipsacus asper Wall
- Inhibitory Effect of Phytochemicals on Abused Drug-induced Dependence
- Neurrprooecttve ffeet oo a utaaol xtrrct rommOpuntia -ficus indicavar . saboten in a Rat Model of Focal Cerebral Ischemia
- Asymmetric Synthesis of Various Aminocyclopentitols as Glycosidase Inhibitors via CSl-mediated Stereoselective Amination
- Comparison of Oral Bioavailability of Genistein and Genistin in Rats
- Constituents from Acanthopanax senticosus Fruits
- Molecular Mechanisms of Dietary Restriction on the Neuroprotection and Hippocampal Neurogenesis
- Microfluidic High-Throughput Screening Systems in Drug Discovery
- Guidelines on the Evaluation of Clinical Trials Anticancer Drugs
- Enantiopure Synthesis of Novel Pseudo-D-vinylcyclopropyl Nucleosides Bearing Quaternary Carbon as Potential Anti-Herpesvirus Agent
- Simultaneous Quantitative Analysis of Bioactive Sphingoid base-l-phosphatey Direct Infusion ESI /MS /MS
- Cyclooxygenase-independent down-regulation of Multidrug Resistance-associated Protein-1 Expression by Celecoxib in Human Lung Cancer Cells
- Development of Novel PPAR ot/y Dual Agonists:Design, Synthesis and Biological Evaluation
- A New Benzylated Flavanone from Cudrania tricuspidata
- Bacterial DNA Containing Methylated CpG Motifs Retains Immunostimulatory Activity in Synergy with Modified L ipopolysaccharides
- The IL -ip-induced IL-32 expression is positively regulated by phospholipase D and p38 MAP kinase
- Identiflcation of Non-phosphorus PTPIB Inhibitors with High Selectivity over TCPTP by Computational Screening of Chemical Database
- Flavonols from Houttuynia cordata with Protein Glycation and Aldose Reductase Inhibitory Activity
- Meliae Corte x Extract Exhibits Anti-a llerg ic Activity through the Inhibit ion of Syk K inase in MastCells
- Effect of Carbon Chain Length on Stability of Ketorolac Enhancer-Prodrugs
- 3D-QSAR modeling and docking analysis of imidazolyl aryl-piperidine derivatives as MCHIR antagonists
- Chemoselective ortho-bromination of phenol in the presence of olefin : Application to the synthesis of Obovatol
- Comparative Effects of Apicidin on Regulation of Cell Cycle Genes in Estrogen Receptor-positive and -negative Human Breast Cancer Cells
- The anti-oxidant effect of ' Chungshinchongyitang' in auditory cells.
- The study of Artemisia capillaris component standard for each growing region,time, part.
- Phytochemical Constituents of Artemisia capillaris
- Effect of Arginine, Cysteine and Lysine on A lcohol Metabolism in Rats .
- National Chemical Library Management System
- Asymmetric Synthesis of Stereoisomeric 3-Hydroxypipecolic Acid Analogues and Their Conformational Analysis
- Synthesis and Anticancer Activity Study of New Xanthone Analogues
- A New Horizon of ProteoChip Technology in New Drug Discovery
- Modulation of P-Glycoprotein Activity by Naturally Occurring Compounds
- Array Comparative Genomic Hybridization Analysis of Cervical Intraepithelial Neoplasia and Cancer
- Studies on Newa Benzene Ring NHE-1 Inhibitors
- Role of IL-6 signaling in the expression of inducible nitric oxide synthase in murine melanoma cell
- Proteomic and phosphoproteomic analysis of PI 3-kinase/Akt signaling in the MCFIOAT lineage : Early events with progressive human breast epithelial cells : Tumorigenic risk and tumorigenesis
- Palladium(II)-CataIyzed Isomerization of Olefin with Hydrogen Donors
- Standardization on Scutellaria baicalensis components
- Anti- inflammatory Effects of Poncirin Isolated from the Fruits of Poncirus Trifoliata in Lipopolysaccharide-Stimulated Raw 264 .7Cells
- Angelicae Gigantis Radix and its ingredient prevent bone loss in ovariectomized rats
- Role of neuroinflammation in the amyloidogenesis in Alzheimer^s Disease
- Epigenetic Regulation of Androgen Receptor and Cell Cycle Regulators in Prostate Cancer Cells by the Histone Deacetylase Inhibitor Sodium Butyrate
- Enantiopure Synthesis of Novel Pseudo-L-vinylcycIopropyl nucleosides Bearing Quaternary Carbon as Potential Herpesvirus Inhibitor
- Virtual Screening for finding Candida albicans isocitrate lyase (ICL) inhibitors
- Effects of SPA005 on chronic ethanol-induced heptotoxicity in rats
- Antioxidizing Activity and Antimicrobial Activity of Catechins from Tea(Camellia sinensis, Diopyros kak i)
- Simultaneous determination of Biological Active compounds in Ostericum koreanum by HPLC and Electrospray Ionization Tandem Mass Spectometry
- Effects of L-Dopa on Dopamine Biosynthesis and Intracellular Cytotoxicity in Pc i2 Cells
- Characterization of Biologically-Active Compound Mixture in Crude Extracts from roots of Codonopsis lanceolata by Fast Atom Bombardment Mass Spectrometry
- study of Cell Mediated Immune Assays to Validate the Efficacy of HPV16 Vaccine Candidates .
- Regulation of TNF-athrough S6K1 Signaling Pathway in RBL 2H3 cells
- Docking and 3-D QSAR studies of dual PDE4-PDE7 inhibitors
- Overexpression of multi-drug resistance protein 2 (MRP2) in tam oxifen-resistant breast cancer cells
- Effects of Bisphenol A on Behavior Alterations, Expression of Estrogen Receptors in Vivo, and Cytotoxicity related to Calcium in Vitro
- Active Anti-inflammatory Components in PONCIRI IMMATURUS FRUCTUS; 25a- and 25b-methoxyhispidol
- Phytochemical study of Humulus japonicus
- The study of origins on Polygonatum species
- Systematic Screening Procedure for Drugs by TLC , LC and LC /MS. ( I ) 40 steroids .
- A new furofuran lignan from Geranium thunbergii Sieb. et Zucc.
- Vasorelaxative actions of isoflavones via Rho-kinase inhibition and K channels opening in vascular smooth muscles of rat aortae precontracted with fluoride.
- Synthesis and evaluation of new series of chalcones as inhibitor of interleukin-5
- Determination of diminazene in bovine, chicken, porcine meat, flatfish and Japanese eel muscle by High-Performance Liquid Chromatography.
- Simultaneous Chira! Discrimination of Multiple p-Blockers by Capillary Electrophoresis in Normal Polarity Mode
- Analysis of mono- and disaccharides in Rehmannia glutinosa Libosch by highhighperformance anion-exchange chromatography with pulsed amperometric detection
- Determination of Nadolol Enantiomers in Human Plasma by Coupled Achiral-Chiral Chromatography.
- Effect of Alcohol Consumption Characteristics on the Body Mass Index and Blood Pressure
- Analysis of Anti-inflammatory, Analgesic and Chondrogenic effects of KD-30, A New Herbal Agent (in vitro and in vivo experiment)
- Influence of Bile Salts and Non-aqueous Vehicles on Solubility and Dissolution of Simvastatin.
- Effect of Subconjunctivally Injected, Liposome-Bound, Low-Molecular-Weight Heparin on the Absorption Rate of Subconjunctival Hemorrhage in Rabbits
- Population Pharmacokinetics of Alendronate in Human Plasma and Urine
- High selectivity analysis method of ginsenosides from panax ginseng by reverse phase HPLC
- Fishing-rod approach to isolating protein targets of bioactive small molecules
- Determination of amygdalin from Armeniacae Semen and Persicae Semen by revers-phase HPLC with Pulsed amperometric detection
- Oleanolic Acid, an Oleanane Type Pentacyclic Triterpenoid, Activates Platelet in a Phospholipase C-Calcium Dependent Signaling Pathway
- Identification of glutathione conjugates and its metabolites of 1-bromobutane in female BALB/c mice by liquid chromatography-electrospray ionization tandem mass spectrometry
- Oncogenic Risk of t e Residual Cellula r DNA in Biotechnological Products
- Cleaning Validation for the Cleaning Procedure
- KJl is a new class of anti-inflammatory compounds with akt inhibition
- YD-107617, a novel PPAR a/y dual agonist, displays potent anti-diabetic activities in vitro and in vivo
- Whitening Effect of Acteoside Is Related to The Inhibition of cAMP Product ion by a -Melanocyte Stimulating Hormone in B16 Melanoma Cells
- A study on the Extracts of Sorbus Commixta L . and and Sanguisorbae Radix along with their physiolog ical activities
- Regulation of CYPIBI promoter activity by hepatic nuclear factor in Hepa lclc 7 cells.
- Mechanism-based Inactivation of Cytochrome P450 3A4 by Natural Product Compounds
- Effects of Constituents of Amomum xanthioides on Gastritis in Rats and Growth of Gastric Cancer Cells
- Dual induction of G ₂/M phase cell cycle arrest and apoptosis by N-(4-methoxy-phenyl)-3,5 -dimethoxy-benamide in HeLa cells.
- Synthesis of androstane derivatives and ant-breast cancer effect
- Use of KHMC-Bigubang to Inhibit Mast Cell-Mediated Allergic Reaction and PMA plus A23187-Induced Inflammatory Cytokine Production
- Design and Synthesis of Chroman-2-carboxylic acid arylamide
- Decreased sphingolipid biosynthesis as potential biomarker for cholesterolinduced hepatotoxicity in mice.
- Design and Synthesis of 5-Substituted-pyridine-2-carboxyIate Derivatives As a Novel Telomerase Inhibitor
- From Development to Approval on Cellular Therapy Products
- Simple High-performance Liquid Chromatographic Method for the Determination of Zaltoprofen in Dog Plasma
- Histamine participates in excitation of sensory neurons via the PLA2/Lipoxygenase /TRPVl pathway
- Involvemant of chemok ine on the opioid receptor - mediated pain perception
- In vitro anti-mycobacterial activity of a new generation of respiratory quinolone ,DW -224a
- Enantiopure Synthesis of Apio Fluoroneplanocin A Analogs as Potential SAdenosylhomocysteine Hydrolase Inhibitor
- Role of acetylcholinesterase in apoptosome formation during apoptosis
- Proliferative and Antiapoptotic Effects of Caragana sinica Extracts on Human Osteoblast-like MG-63 cells.
- Antiplasmodial activity of novel stilbene derivatives isolated from Parthenocissus tricuspidata from South Korea
- The standardization of domestic Angelica dahurica depending on areas
- Suppressive effect of demethoxycurcumin and bisdemethoxycurcumin on expressions of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX-2) in RAW 264,7 Macrophage Cells
- A Study of the factors causing the increase in redundant-Stock-M edicine and the solutions
- Inhibiting activity of essential oil from Artemisia iwayomogi against antibiotic- resistant bacteria
- Tissue Factors from Medicinal Plants
- Applications of the Chiral Monofluoro Structural Unit in Biochemistry and Medicinal Chemistry
- Isoprenylated Flavonoids Isolated from the Root Bark of Erythrina mildbraedii
- Enhanced Invasiveness in Drug-Resistant Acute Myelocytic Leukemia Cells via the Increased Expression of Matrix Metalloproteinase-2 and -9
- Platycodon grandiflorum Prevents Concanavalin A-Induced Hepatitis in Mice
- Impaired Ca signaling in cryopreserved swine sperm
- Anti-inflammatory and anti-painful effects of Ostericum korearnum Maximowicz against lipopolysaccharides induced inflammation .
- Changes of gene expression profiling in octachlorostyrene treated Caenorhabditis elegans with whole genome microarray and real time RT- PCR
- Genotyping of Human Papillomavirus with Multiplex Liquid Bead Array system .
- Therapeutic Effects of Schizandra chinensis Fruit on DSS-Induced Colitis
- Stress Decomposition Studies on Terazosin Hydrochloride and Behaviours of it's Related Substances.
- Chromatographic Enantiomer Resolution Using Covalently Immobilized and Coated Polysaccharide Derivatives as Chiral Stationary Phases in HPLC with Fluorescence Detection
- Solubility Improvement of Tacrolimus by Solid Dispersion Systems
- The Comparative Study on Post-Marketing Surveillance System for Pharmaceuticals
- Effects of epigallocatechin on the pharmacokinetics of verapamU after oral and intravenous administration in rats
- Kinetic Analysis of the Hepatic Uptake and Biliary Excretion of 11-hydroxyaclacinomycin X (ID6105) in Rats
- Anti-proliferative activity of diterpenes from Biota orientalis leaves on hepatic stellate cells
- Development of high sensitivity analysis method of mono- and di-saccharide by reverse phase-HPLC with Pulsed amperometric detector
- Simultaneous Analysis of SD-2007 and Its Metabolite, Apicidin, in Rat Serum Using a Liquid Chromatography/Tandem Mass Spectrometry: Application to a Drug-Metabolite Kinetic Model
- Synthesis and Biological Evaluation of N-Formyl Hydroxylamine Derivatives as Potent Peptide Deformylase Inhibitors
- Blend Uniformity Analysis : Validation and In-Process Testing
- The Korea-U.S. Free Trade Agreement (KORUS FT A) May Raise the Price of Medicine and the Public's Medical Expense.
- Antithrombotic and Antiplatelet Activities of Korean Red Ginseng Extract
- Biological Characterization of Long Term Cultured Human Mesenchymal Stem Cells
- HMC05, water extract of a modified herbal formula from Banhabackchulchunmatang, inhibits TNFa-induced monocyte adhesion to endothelial cells
- Equisetum hiemale Inhibits Inflammatory Responses in PMA and A23187 induced HMC-1 cells
- A Studies on the Instrumental Analysis of Antibiotic Drugs
- Osteoblast Differentiation Simulatory Constitents of Eclipta Prostrata
- Isolation and Quantitative Determination of Analysis Marker from Water Extract of Mori Cortex Radicis
- Absorbance Increase Effect of Azo and Anthraquinone Derivatives at 582nm on the Spectrophotometric Analysis of Unimark 1494DB
- Column-switching high-performance liquid chromatographic analysis of azasetron in rat plasma by direct injection
- Evaluation of CMC in the Clinical Trials
- Plasmacytoid Dendritic Cell Biology : An Overview
- Policy Direction and Strategies of the Drug Sector in KORUS FTA
- Up-regulation of Cyclooxygenase-2 Expression by 1-Bromopropane in Macrophages
- Immunomodulatory effects of Cordyceps militaris mycelium in macrophages
- Immunogenicity of PRP-TT Hib vaccine in Juvenile rhesus monkeys
- West Nile viral capsid protein induces cell apoptosis via NO-mediated death pathway in SH-SY5Y neuroblastoma cells
- Comparative studies of cell viability assay using human dermal f ibroblasts and human mesenchymal stem cells
- Synthesis and antifungal activity of lH-indole-4,7-diones
- Enantioselective Synthesis of (R)- and(S)-a-Alkylcysteines based on Aryl-2-thiazoline-4-carboxylic acid tert-Butyl ester via Phase-Transfer Catalytic Alkylation.
- Modification of Exendin-4(l-39) with bile acid for Ing-acting therapeutic aent in type-2 diabetes
- The Role of Repressor of GAT A (ROG) in T Cell Activation
- Alkaloids from the Korean Aconitum Plants
- Anti-oxidative and nitric oxide production inhibitory activities of phenolic compounds from roots of Rhododendron mucronulatum
- Simultaneous determination of five coumarins in Angelicae dahuricae Radix by C30 reversed-phase HPLC/UV and LC-MS/MS
- Antibacterial Activities of Essential Oils from Chrysanthemum indicum against Anrtibiotic Resistant Strains
- Preparation of Floating Microspheres for Fish Farming
- Label-Free Protein Chips to Hits
- Hepatitis B virus X protein-mediated MDRl activation: Potential role of C/EBPp
- Identification of distinct gene expression patterns in tamoxifen-resistant MCF7 cells
- Receptor-Mediated Gene Delivery by Folate-PEG-Baculovirus in vitro and in vivo
- Quercitrin gallate inhibits peroxynitrite production in zymosan A-stimulated macrophages RAW 264 .7
- Analysis of Protein Profile s in Terfenadine-Treated Rat Cardiomyocytes
- Inhibition of Sortase by CM-I -135 on the Virulence of Staphylococcus aureus in Mouse Model of Infection
- Chiisanogenin Induces Caspase-dependent Apoptosis in Human Promyelocytic Leukemia HL -60 Cells
- Comparative bio availability of two clopidogrel formulations in healthy male volunteers; Comparison between clopidogrel and its metabolite carboxy clopidogrel as pharmacokinetic parameter
- Kaempferol modulates age-related NF -kB activation
- A Simultaneous Determination Method of Marker Compounds in Turmeric(Curcuma longa L.) by High Performance Liquid Chromatography-Diode Array Detection
- Biological Function of Daumone in C. elegans
- Simultaneous analysis of bioactive components from Astragali Radix by high performance liquid chromatography with UV detector and tandem mass spectrometry
- Effects of daidzein on TCDD-induced immunosuppression
- Selection of Angiopoietin-2 Neutralizing mAbs from Human Phage Antibody Library
- The Influence of Size of Solid Lipid Particles upon Pharmacokinetic Behavior of Genistein
- Role of COX-2 in BH 4- induced Dopaminergic Neurodegeneration ; Implication for Parkinson's Disease
- cDNA cloning and characterization of Estrogen receptors(ER a and ER b) in Slender bittering (Acheilognathus lanceolatus)
- Correlation between VEGF and AGE in retina and serum of STZ-induced diabetic rats
- Quantification of Donepezil in Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry
- Quantitative analysis of acetophenones from Cynanchum wilfordii H emsley.
- Effects of Scutellariae Radix on gene expression in macrophage cell line using microarray.
- Comparison of Non-saponin Composition and Contents in Fresh Ginseng Roots Cultivated in Different Areas and at Various Ages
- Simultaneous Profiling Analysis of Multiple p-Blockers as Ethoxycarbonyl/Trimethylsilyl Derivatives by Gas Chromatography-Mass Spectrometry in Selected Ion Monitoring Mode
- Development of coated dexibuprofen (S-(+)-ibuprofen) dry elixir as a long acting oral delivery with enhanced bioavailability
- Determination of losartan in human plasma by liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS) method : bioequivalence assessment.
- Anti-diabetic Effects of Mechanisms of MEG
- Activation of ex-vivo cultured mur ine bone marrow -dendritic cell by Paecilomyces tenuipes
- 국내에서 재배하는 수종의 한약재에 대한 산지별 항균효과
- Simultaneous Analysis of Glycyrrhizin and Baicalin in Eulja-Tang (乙字湯)by HPLC
- Simultaneous analysis of bioactive components from Paeoniae Radix by high performance liquid chromatography with UV detector and tandem mass spectrometry
- Sulfur Dioxide Flowed in the Processing of Oriental Herbal Medicines
- Mass Spectrometry-Based Targeted Metabolic Profiling in Placenta of Woman"s Delivery with or without Labor
- Gene Expression Profiles of RAW264.7 Cells Teated with Compounds Isolated from Astragalus Membranaceus Bunge
- Oral Absorption and Pharmacokinetics of H-1018, an HMG-CoA Reductase, in Mice
- Bioequivalence of baclofen by liquid chromatography-electrospray ionization tandem mass spectrometry
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