학술논문
Pharmacokinetic and PK/PD modeling of dihydropyridine calcium channel blocking agents in cardiovascular effect.
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- YUN Min-Hyuk YUN Hwi-Yeol KANG Won Ku KWON Kwang-il
- 간행물 정보
- 『추계총회 및 학술대회』(2005년) vol.2, 530~530쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2005.11.30
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- Synthesis and biological evaluation of quinoxaline -5 ,8 -diones that inhibit vascular smooth muscle cell proliferation
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- An olefin disconnection strategy for the practical synthesis of (+ )-brefeldin A ： cross metathesis and intramolecular Homer-Wardsworth -Emmons olefination
- Screening and Identification of PTPIB Inhibitory Natural Products for the Treatment of Type 2 Diabetes
- Sulforaphane inhibits phorbol ester-induced COX-2 expression in human breast epithelial cells ：IkB kinase p as apotential target
- C y c looxygenase -2 inhibition attenuates lipopolysaccharid e -induceddopaminergic toxicity.
- Effect of Sophorae Radix on anti-40CD and recombinant interleiikin-4- induced cytokine production in murine B-cells
- Quantitative analysis of anthraquinone and stilbene deriva ives in various rhubarbs
- Protective Effect of Tissue Cultured Root of Mountain Panax ginseng C A . Mayer against 2 ,3 ,7 ,8 -tetrachlodibenzo -p -dioxin Induced Toxicity in Rat
- Reduction of oncogene expression in cancer cells using siRNA delivery systems
- Dose Dependency in the Oral Bioavailability of an Organic Cation Model, Tributylmethyl ammonium (TBuMA), in Rats
- Molecular Cloning of the Gene Encoding the Thermostable L-Asparaginase from Streptomyces lincolnensis M -20
- Genexol-PM , a polym eric micellar paclitaxel formulation, suppresses primary tumor growth and lung metastasis in a green fluorescent protein orthotopic model of breast cancer
- Virus Validation for Plasma Derivatives
- Bisphenol A -in duced immunosuppression in 7 -weeks -old offsprings of mice.
- Fatal Poisoning Cases due to Benfuracarb or Furathiocarb Ingestion
- Isoflavonoids Isolated from Pueraria Radix Is Potent Inducer of Heme Oxygenase -1 And Nrf2/ARE Signaling.
- Comparative Evaluation of Scoring Functions for Virtual Screening
- The inhibitory effect of the biologically active components from Oriental medicines on the m icroglial activation
- Hepatic geneex pression profiles study in the mouse liver by acute ethanol exposure induced steatosis
- Effects of Aster spathulifolius extracts (ASE) on fat accumulation, lipid profiles and UCP expression in high fat diet induced obese rats
- Endotoxin Induces Downregulation of TNF -a/iL-10 and Increased P oduction of IL -6 in P ristane-Primed Chronic Inflammation ICR Mice
- Form aldehyde-Induced gene expressio n in Human Trachea Hs 680 Cell Line
- Effects of L-DOPA on dopamine biosynthesis and cytotoxicity in PC12 cells
- Reduction o f mechanical pain by spider toxin
- Potent anti-breast cancer activity of a novel inhibitor of HD AC, IN -2001 in vivo MMTV /c-Neu mice
- Amelioration of age -related inflammation and oxid ative stress by PPARy activator : Suppression of NF -kB by 2,4-thiazolidinedione
- INHIBITION OF ANTTOXIDANTS AND CYP450 INHIBITORS AGAINST AIRBORNE PARTICULTE EXTRACT-INDUCED GENOTOXICITY
- Rho K inase Activation during Acetylcholine-induced Contraction of Cat Esophageal Smooth Muscle
- Comparison o f Sim ultaneous Extraction Methods for Basic Drugs in Biological Specimens
- Berbamine inhibits rat aortic vascular smooth muscle cell proliferation and cell cycle p rogression through inhibition of ERK l/2 activation and Rb protein phosphorylation
- The Effect of DA -8159 , a Novel PDE5 Inhibitor, on Erectile Function in th e Rat model of Hypercholesterolemic Erectile Dysfunction
- A denovirus mediated p53 treatment enhances photodynam ic antitumor response
- Photodynamic effects of Radachlorin on cervical cancer model
- Effect of A 0054E on Quinone Reductase [(NAD(P)H ： quinone oxidoreductase, OR] and on H ydrogen Peroxid e-induced Oxidative DNA Damage
- Protection of EGCG and ginsenoside Rgl against oxidative stress by th emodulation of ceram ide level in LLC-PK l cells
- In Vitro and In Vivo Antifungal Activities of Itraconazole-PM , a Polymeric Micellar Formulation of Itraconazole
- AMPK -mediated Cell Death by Metformin under the Condition of Oxidative Stress：Inhibitory Role of AMPK in Phase II Antioxidant Enzyme Induction
- Contents of Heavy Metals in Commercial Herbal Medicines in Seoul
- Determination of AUantoin in Dioscoreae Rhizoma by HPLC
- Monitoring(n) of Pesticid e Residues in Commercial Herbal Medicines
- The effect of shampooing on concentrations o f Methamphetamine and MDMA in human hair
- Role of de novo ceram ide synthesis in SK-1-induced apoptosis
- Estrogenic Effects of Marijuana Smoke Condensate (MSC) and Cannabinoid Compounds
- Role of Oxidative Stress in Peritoneal D ialysis Solu tion -induced Peritoenal Alteration
- Integration system for ageing research based on distance einalysis between factors
- A Short and Efficient Synthesis of L-Carbohydrates
- Dependence, neurotoxicity and memory impairment induced by dextromethorphan.
- Effect of extract from Punica granatum and some herbal extracts mixture on general postm enopausal symptom in vitro.
- Development of Controlled-Release Pellets with Sodium Alginate and Surelease？？ using Extrusion/Spheronizatdon
- Expression Profiling of Cellular Process in Squamous Cervical Cancer Omic Approaches and Its Correlation with Array-CGH
- Quantitative Determination and Structural Identification of Ten Major Saponins in Platycodi Radix by HPLC with ELSD and LC-ESI tandem MS
- Novel Anti-Depressant Effects of Nelumbinis Semen
- Determination of famotidine in human plasma by high-performance liquid chromatography.
- T e Role of Phospholipase A2 and Its Metabolite in Histam ine Release in RBL 2H 3 Cells
- 3D-QSAR study of 2- Phenyl- 1,8 -naphthylridin-4 -one with anticancer activity
- Transcriptional configuration o f m ou se cerebral cortex by long -termex posure to 3, 4 -m ethylenedioxym etham phetainine (MDMA) through gene expression profiling
- Risk Assessment of Heavy metals in PM 2.5 and PMIO
- Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice
- Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1 -expressing glioblastoma cells
- Screening of pharmaceutical excipients on hepatic metabolism of olanzapine, in vitro
- Cryptotanshinone, One of the Major Ingredients of Salviae Miltiorrhiza Bunge(Dansham),Inhibits Rabbit Platelet Aggregation by Reducing Intracellua Ca Mobilization and Arachidonic Acid Liberation
- Anti-wrinkle E ffect of Acanthopanax extracts in Human Dermal Fibroblast,
- Determination of eperisone in human plasma by liquid chromatography-tandem mass spectrometry
- Drug Discovery at the Interface between T\imor Immunity and Autoimmunity
- Panax ginseng increases hypoxia-induced dow nregulated cellular response related genes in human neuroblastom a cells
- Rapid Screening of blood-brain barrier penetration of drugs using the immobilized artificial membrane phosphatidylcholine column chromatography
- Effect of morin on the paclitaxel bioavailability after oral and intravenous administration of Paclitaxel in rats
- Anti-diabetic Effect and Mechanisms of KHP-03
- Inhibition of tyrosin ase activity by N ,N -iansubstituted selenouread erivatives
- A ntitum r Constituents from the Bark of Tilia amirensis
- Single Nucleotide Polymorphism (SNP) Detection In Microfluidic Device Using Poly(NIsopropyDAcrylamide As Pseudostationary Phase
- Evaluation of cholesterol in hair of patients with hyi>ercholesterinemia
- Crystal Structure of Prophenoloxidase Activating Factor-II, a Clip Domain Family of Serine Protease
- Rapid determination and validation of losartan in human plasma by liquid chromatographytandem mass spectrometry and its application to a bioequivalence study
- Heme Oxygenase-1 Induction by YS 51, An Analogue of Higenamine, Inhibits Nitric Oxide-Induced Apoptosis of ROS 17/2.8 cells
- Changes of Gene Expression Related to Cisplatin Resistance in Gastric Cancer Cell
- Synthesis and screening of cyclooxygenase activity of 9-amino-l,2 ,3 ,4- tetrahydroacridine derivatives.
- Immuno-modulating effect of Mountain cultiired ginseng
- Nrf2 Protects against Oxidative and Nitrosative PC12 Cell Death through Up-regulation of -Glutamylcysteine Ligase and Heme Oxygenase-1
- Pharmacokinetics of gabapentin in Rat with Acute Renal Failure Induced by Uranyl Nitrate
- Enhanced anticancer efficacy of a-tocopheryl succinate by polyethylene glycol conjugation
- Nicotine attenuates kainate-induced neu rotoxicity via activation of a7 nAChR in the rat.
- Characterization of Immune Responses Induced by Intramuscular Vaccination with DNA Vaccines Encoding Measles Virus Hemagglutinin and/or Fusion Proteins
- Synthesis, Structure-Activity Relationships, and Mechanism of Action of Novel Indirubin Derivatives as Potent Anti-proliferative Agents with CDK2 Inhibitory Activities
- Small-Molecule Inhibition of Siderophore Biosynthesis in Mycobacterium tuberculosis and Yersinia pestis
- Synthesis and Cytotoxicity Test of Xanthone Derivatives as Anticancer Agents.
- Activities of the Novel Oxazolidinone Analogues Against Staphylococcus aureus in Murine S ystemic Infection Model
- Effect of L-Carnitine Supplementation on Cardiac Carnitine Palm itoyltransferase Activities and Plasma Carnitine Concentrations in Adriamycin Treated Rats
- Quantitative analysis of oxidation dye components in hair dyes
- Relatively high amount of IL-3 2 q isoform is constitutively produced in human T cell leukemia cell line Jurkat compared with other human cell lines.
- Pulmonary delivery of Lys^-mono-PEGylated glucagon-like peptide-1 (7-36)： Hypoglycemic effect and pharmacokinetics
- Phenolic Constituents from Tetragonia tetragonoides
- Red wine polyphenolic compounds strongly inhibit pro-MMP -2 activation in response to throm bin via direct inhibition of MTl-MMP in vascular smooth muscle sells
- Acteoside of Callicarpa dichotoma attenuates scopolamine -induced memory impairments
- Comparison o f M oxifloxacin Monotherapy versus Cephalosporin - A zithrom ycin Combination Therapies for Community Acquired Pneumonia
- In hibitory Effects of Paeonol on Morphine-Induced Reverse Tolerance and Conditioned Place Preference in Mice
- A study on evaluating quality of service in pharm acy using SERVQUAL
- Consideration of Physical and Biological Factors for Oral Drug Bioavailability
- Pharmacokinetic and PK/PD modeling of dihydropyridine calcium channel blocking agents in cardiovascular effect.
- Treatment with FermentaGinseng Decreases Colonic Inflammation in the Murine Model of Ulcerative Colitis
- Enhanced Cellular Uptake of Cytarabine via a Petidyl Prodrug, L-Valyl-Cytarabine in Caco-2 Cells
- Inhibition of Diacylglycerol Acyltransferase by lupane type triterpenoids from the bark of Betula platyphylla var. japonica
- A Molecular Mechanism for Hair Growth Effect of Minoxidil
- The Stability of cefditoren pivoxil in Tylenol？？ and Febron？？ oral liquid syrups
- Role of Cadherins in Bone Biology
- Deterzniiiation of sildenafil, tadalafil, vardenafil and their analogues in food marketed for penile erectile dysfunction by HPLC-UV
- Cytoprotection against oxidative damage by Nrf2 - regulated genes: Induction of the 26S proteasome
- The Cytotoxic Saponin from Heat-Processed Achyranthes faurici Roots
- Studies on Target Microbial Contamination of Herb Medicines
- Hepatoprotective Effects of Chrysanthemum indicmn Liime Extract in Rats treated with CC14
- The Effect of Taurine Chloramine on PMA -elicited Superoxide Anion Production： T au-C l Modulates NADPH Oxidase A ssembly
- Monoclonal Antibody and Its Therapeutic Approach
- Enantioseparation of Urinary Naproxen and 6-0-Desmethylnaproxen as Diastereomeric (R)-(+ )-1 -Phenylethylamides after Oral Administration of (S)-Naproxen by Achiral Gas Chromatography
- Analysis of depiorination of guanine-b ased nucleosides with 2-bromopropane and other structurally similar halogenated alkanes at the physiological condition by using HPLC and LC/MS/MS.
- Synthesis and In Vivo Evaluation of Selenoflavanone
- Developement of Metalloproteinase Inhibitors from a Fungal Metabolite, Gelastatin
- Chemistry of Plant Polyphenols in Foods and its Contribution to Human Health
- Construction of Thesaurus for Human Gene and Protein Nomenclatures
- Regulation of Transduction Efficiency by Pegylation of Baculovirus Vector in vitro and in vivo
- AKAP12 down -regulates the H IF -la stability
- Anti-hepatofibrotic effect of Rhus vemiciflua Stokes flavonoid extract in human hepatic stellate c e ll line, LI90 and hepatom a cell line, HepG2 cells
- Involvem ent of K ,Cr-Cotransport-Mediated Generation of Reactive Oxygen Species in M elan ogen esis Induced by A pigenin in B16 Melanoma Cells
- Neuroprotection of ginsenoside Rg3 and signal evidences in neuroblastom a cell line (SK-N -MC )
- A Pharmacokinetic Study to Compare the Absorption Characteristics of Single-, Multi-dose of Transdermal Nicotine Patches
- The protective effect of QGC on gastritis in rats.
- Identification of Taxol-Resistant Genes in Mouse Fibroblasts Transfected with a cDNALibrary from Breast Cancer C ells
- Anti-inflammatory Activity of Punica granatum Extracts ( I )
- Effects of Dicyclomine on Methamphtamine-lnduced Behavioral Sensitization and Dopamine Release as Measured by in vivo M icrodialysis in Mice.
- Synthesis and Cytotoxicity of Novel Cyclic Ceramide Analogues
- Application of a Sample Pooling Method for the Accelerated Assessment of the Rate of Uptake of Drugs by the Brain in Rats
- Structural, biological, and glucodynamic properties of [N-bile acid Lys] human insulin analogues
- Structure-Activity Relationships of 4 '-Thionucleosides As Potent and Selective Human A3 Adenosine Receptor Agonists
- Mechanism of prolonged gene expression by Epstein -Barr v irus-based plasm id in porcine cells
- DNA Gyrase and Topoisomerase IV Are Dual Targets of DW -224a in Streptococcus pneumoniae
- Tota l Synthesis of PM -94128
- Subacute Im munotoxicity of a Synthetic Propenone Compound, -Furan-2-yI-3-Pyridin-2-yl-Propenone in Mice
- The Effects of Carbapenems on the Pharm acokinetics of Valproic Acid
- Synthesis, Pharmacology and Molecular Modeling of New Piperidine derivatives for A lzheimer's disease the rapeutics
- Feasibility Studies for Buccal Transport of Paclitaxel： Influence of Vehicles and Permeation Enhancers
- Involvement of h istaminergic nervous system in the anxiolytic- like activities of Morus alba L. leaves in mice
- Comparative Studies of Intracellular Trafficking Pathways of Dopamine D2 and D3 receptors
- Development and Validation of a Bioanalytical LC-MS/MS Method for the Quantitative Determination of Amisulpride in Human Plasma
- Effects of 2, 4 -D and DCP on the DHT -induced androgenic action
- CCR5 -mediated promotion of neurogenesis of neuronal stem cells by cytokines and chemokines released from astrocytes
- Geranti Bio -Ge Y east, Dried yeast containing Biogennaniiun. enhances the production of Antibody via more B cell proliferation
- Kainate-induced hippocampal mitochondrial degeneration is more susceptible to senile-prone (P8) strain than senile -resistant (Rl) strain of senescence-accelerated mice.
- A new paradigm of Biphenyl Dimethyl Dicarbohydrate as an antiviral agent
- Chemical and Physiological Synthesis of N 3-Adenine Adducts by 1- and 2-Bromopropane, and A nalysis of their Adenine Adducts by HPLC and LC/MS/MS
- Topical delivery of IL-13 AS-ODN with cationic elastic liposome for the treatment of atopic dermatitis
- Pandemic Preparedness: Immune Responses of Live Influenza Vaccine
- 2"-Hydroxycinnam aldehyde inhibits SW620 colon cancer cell growth through prevention of AP -1
- DNA-Based Immunotherapy for Chronic Disease Such as T\iberculosis
- Revised Provision for SpeciHcations and Test Procedures of Drugs
- Correlation of Serum Thyroglobulin before the 1st 1-131 Remnant Ablation and Change of Thyroglobulin and C ervical 1-131 U ptake after Abladon
- Activation of NF -kB by HDAC inhibitor apicidin through Sp1 - dependent d e novo protein synthesis: its im plication for resistance to apoptosis
- PTPIB inhibitory effect of lignans isolated from Myristica fragrans
- Formulation and Evaluation of solution Preparation containing Ivermectin
- Rapid, simple and highly sensitive LC-ESI/MS/MS method for the quantitation of buspirone in human plasma： application to a pharmacokinetic study
- A Role for "Local" Protein Synthesis in Synaptic Plasticity, Learning & Memory
- Rubiae Radix Suppresses the Activation of Mast Cells through the Inhibition of Syk Kinase for A nti-allergic Activity
- Inhibitory effects of the stembark extract of grapevine on the proliferation of human tumor cell lines
- Epothilone B and D arrest cell growth via inhibition of N F -kB signaling pathway in SW 620 cells
- In hibitory effect of CBPharm -001 on lipopolysaccharide -induced cognitive dysfunction and its action mechanism
- Synthesis of Vermiculine and It"s Derivertives via Making Macrodiolide Conformation with selenol ester
- Docking of a series of norindenoisoquinoline topoisomerase 1 poisons into human topoisomerase I with FlexiDock
- The Formononetin Content Comparison of Astragali Radix with different cultivated regions by cultivated GAP(Good Agriculture Practice )
- Sialoglycoprotein-binding protein from the edible mushroom Cordyceps militaris
- Separation of N-FMOC a-amino-acids enantiomers by Liquid Chromatography and Capillary Elelectrochromatography
- Analysis of losartan in human plasma using high-performance liquid chromatography with fluorescence detection
- Inhibition of COX -2 Down-regulates cAM P-induced TRANCE Expression in Osteoblasts
- Anti-proliferative effects of the lignan components from Myristicae Semen on cultured human tumor cell lines
- Influence of Nelumbo nucifera GAERTN on the Response of Stressful Stimuli.
- Total synthesis of (+ )-macrospheldie A and B
- Studies on Immuno-Modulatoryand Antitumor Effects of Salicomia herbacea Extract
- Binding affinity test of aminoglycoside antibiotics to the HIV-1 Rev Responsive Element
- Enantioseparation and evaluation of naproxen by HPLC
- Sensitive column-switching high-performance liquid chromatography method for determination of propiverine in human plasma
- Development and Validation of HPLC-UV method for the Determination of Tranilast in Pharmaceutical Preparations
- Design, Synthesis and Biological Study of Novel Psorospermin/Quinobenzoxazine Hybrid Compounds
- Phytochemical Constituents of Prunus padus
- Reactive oxygen species mediate ET-1- induced activation of ERK l/2 and SAPK /JNKs signaling in cultured felinee sophageal smooth muscle cells.
- Immune-Enhance Effect and Its Mechanism of Scrophularia Buergeriana .
- Modulatory Effect of Coffee Diterpene Kahweol on A cute Inflammation in The Rat Air Pouch Model
- Triphlorethol-A Activates Heme Oxygenase-1 in Lung Fibroblast Cells via Up-Regulation of NF-E2 Related Factor 2
- Biotechnological Product Assistance Project- from Bench to Brand
- Structures of Enzymes and Drug Discovery
- Single pathogenic bacteria detection using a compact CMOS biochip system
- Eupatilin,a pharmacologically active flavone derived from Artemisia plants , protects cultured felin e ileal smooth muscle cells from indomethacin.
- A New Drug for Luminal Amoeb asis ： Synthesis and Properties of Dextran-Metronidazole Succinate as a Colon -Specific Prodrug of Metronidazole
- Pharmacokinetic Modeling of Testosterone Metabolism using Primary Cultures and Cryopreserved Hepatocytes
- Identification of a novel form of 30 kDa membrane-associated and neutral sphingomyelinase and its role inexocytosis mechanism of neurotransmitter
- All-trans Retinoic Acid Overcomes a Doxorubicin -Resistant Phenotype via Induction of Fas /Fas L igand System in Acute Myelocytic Leuke ia Cells
- Prenylflavone Derivatives from Psoralea Corylifolia Inhibit Nitric Oxide Synthase Expression through the Inhibition of IKB Degradation in Activated Microglial Cells
- Enhanced solubility of paclitaxel in the liposomes： effect of the composition
- Cytotoxic Phenylpropanoids from the Rhizomes of Alpinia galanga
- Potent Inhibitory E ffects of N -A ryl S-A lkylthiocarbamate Derivatives on Melanin Production
- Possible role of ceramide in lung injury induced by diesel exhaust particles
- The Pharmaceutical Effects of Antimicrobial Molecules from Arthropoda
- Modulation of P-glycoprotein Activity by Kaempferol Derivatives
- Effect of Piogiitazone on Cerebrovascular Blood Flowin Type 2 Diabetic Patients
- Glycosylation pattern of recom binant CTLA4Ig from transgenic rice cells
- Role of Monocarboxylic Acid Transporters in the Intestinal Absorption of Carboxylic Acid Drugs
- The Validation of Anti-Cancer Targets by Clinicopathological study: TGF-P Signaling in Gastric Carcinoma
- Isolation of Butein from R hus vemiciflua and Synthesis of Its Derivatives w ith Anti-inflammatory activities by inhibiting production of Nitric Oxide
- B ifim ctional e ffect of resveratrol on theexpression of ErbB 2 in human breast cancer cell
- IdentiHcation of Novel Targets for Cancer Therapeutics through Genome Expression Profiling
- A new norditerpenoid alkaloid from Aconitum sp. cultivated in Korea
- A nticolitic effect of Ginseng
- Effects of D i(n-butyl)phthalate on Gene Expression of the Male and Female Reproductive Organs
- N -Glycosylation Analysis of Recombinant Human Tissue Plasminogen Activator Produced in Urea Cycle Enzymes Expressing CHO Cell Line
- The study of metabolite-to -parent drug ratios of Methamphetamine and Methylenedioxym etham phetam ine in hai
- The Smoking-Related Factors and Smoking Cessation in Korea
- Critical Domains in the Heterotrimeric G protein Subunit for Interaction with Receptors and Effectors
- Revised Provision of Stability Test
- Diememorfan, a dextromethorphan analog, attenuates methamphetamine-induced dependence and dopaminergic toxicity via the inhibition of cannabinoid CB 1 receptor
- Alkamides, ACAT inhibitors from the fruits of Piper nigrum
- Effect of a natural extract on symptoms of the alcohol hangover
- Molecular Mechanism of Na,K-ATPase Inhibition by Ouabain：Ouabain Dephosphorylates Cofilin through the Ras/MEK/ERK Pathway
- Inhibition of human secretory non-pancreatic phospholipases A2(PLA 2) Involved in inflammation
- Kidney Medulla-Specific Reduction in the Distribution of TEA in rats with Uranyl nitrateinduced Acute Renal Failure.
- Synthesis of New 3 -Alky amino -6 -allylthiopyridazine Derivatives
- Inhibitory effects of madecassic acid on the productions of NO, PGE2, TNF -a and IL-lp via the suppression of NF -kB pathway in LPS-induced macrophages
- Studies on Comparative Analytical Methods for Minerals in Multi-Vitamins with Minerals Pharmaceuticals
- p38 MAPK Mediates Ceramide-induced Apoptosis through the Phosphoinositide 3 -k inase-Akt Pathway
- Discovery of a Novel PPARy Agonist, KR62980 with New Indication of Osteoporosis Treatment
- Effect of Traditional Herbal Medicine on the Formation of Advanced Glycation Endproducts (AGEs) in Vitro
- Asymmetric synthesis of 1,2 -diol and its app ication to the synthesis of (+ )-clemastine
- The T\imor Suppressor, p l6 Prevents Cell Transformation Through Inhibition of c-Jun Phosphorylation and AP-1 Activity
- Preparation and evaluation of clavulanic acid-loaded Eudragit^ microspheres for sustained release and enhanced stability
- Stealth Cell Delivery for Self-Regulating Glucose Level
- Induction o f G lutathione S - Transferase in IGF type I receptor overexpressed hepatoma cells
- A 24-nor-Triterpenoid from the Steins of Rumex japonicus with Advanced Glycation End -products (AGEs) Inhibitory Activity
- Hepatoprotective Effects of Viticis Fructus Extractin Rats treated with CC14
- In Silico Screening of Angiogenesis-related Genes in Hepatocellular Carcinoma using Protein Interaction and Expression Data Base
- Immunosuppressive effect of poly(RGD) sequence on allogenic CTL induction in mice
- Development of Anti-arthritic Therapeutics from Saponins
- TGF -p Modulates Expression of MMP-2 and MMP-9 through p38 Signaling in Breast Epithelial Cells
- Chemical modification of santonin confers the ability to in duce the differentiation of human promyelocytic leukemia cells： Involvement of N F -k B, PKC, ERK an d PI3 -K
- LY2821 Inhibits Rat Aortic Vascular Smooth Muscle Cell Proliferation by Upregulation of p27
- Regulatory Effects of K Jl on Macrophage-mediated Immune Responses
- Mechanism of Functional Impairment of the Rat Taurine Transporter by Nitrogen Oxide: Evidence for the Activation of Nitrogen Oxide by Superoxide
- Toxicogenomics Concepts and Applications to Develop New Pharmaceuticals
- The Effect of Taurine Chloramine on LPS-Induced NO Production： Tau -C l Regulates Ras-ERK-NFkB Signaling Pathway
- Antioxidant Properties of Ttingtungmadic Acid Isolated from Salicomia Herbacea
- Prevalence and Determ inants o f Influenza Vaccination in Koreans
- Development of Anti-Bacterial Agents by Using Structural Information
- Implementation strategy for the regulations on the package unit for the medicine
- In vitro and in vivo anti-inflam m atory activity of Q -linolenic acid isola ted from Actinidia polygam a fruits
- Evidence that Protease-activated Receptor -2 M ediates Trypsin -induced Reversal of Stellation in Cultured Rat A strocytes
- ERK-m ediated production of neurotrophic factors by astrocytes promotes neuronal stem cell differentiation by ery thropoiein
- Physicochemical characteristics of solid lipid nanoparticles loaded with isotretinoin for topical delivery
- Synthesis of Arginine-grafted Dendritic Block Copolymer for Gene Delivery and Its Cellular Uptake Mechanism Leading to Effective Transfection.
- Synthesis of N -Phenylsuccinimide Derivatives as Novel T- type Ca Channel Blockers Based on SBDD
- Revision of the Korean Pharmaceutical Codex, The third Edition
- Quantitative Analysis of Polygonati Rhizoma
- Functional role of a novel form of 60 kDa Mg-dependent neutral sphingom yelinase
- In Rabbit M icrofracture Model Controlled Dehydroepiandrosterone-sulfate Release from PLGA Rod -type Implant Enhanced Cartilage Regeneration
- Identification of the Insulin Signaling Cascade in the Regulation of A lpha -Class Glutathione STransferase Expression in Primary Cultured Rat Hepatocytes
- Effect of gamma irradiated phyticacid on the function of immune cells
- Discriminating the Molecular Basis of Hepatotoxicants through Expression Profiling Analysis
- Protection and therapeutic effects of the herbal preparations containing bacalein and 6 -gingerol in the treatment for dermatits
- Metabolism of Tryptanthrin a Cyclooxygenase -2 Inhibitor in Rats in Vitro
- In-line Monitoring the Mixins Ratio of UFT Granules in Final Product Packages by NIR Spectroscopy
- Akt-G SK 3p pathway underlies the cardioprotective effect of KR -32568 , a novel sodium/hydrogen exchange r-1 inhibitor, in an isolated rat heart m odel of ischem iaand reperfusion heartinjury
- Post-marketing Surveillance Study of the Safety and Efficacy of Mesoglycan Prescribed in Primary and Secondary Care of Patients with Vascular Disease.
- Growth hormone releaser attenuates memory impairments via phosphorylation of A KT/G SK3b and activation of muscarinic Ml receptorin the genetic model of aging gene K lotho mice.
- Enhanced oral bioavailability of poorly water-soluble piroxicain by sodium hyaluronate- based solid microsphere using spray-drying method
- Prescription Order for Splitting Use of Tablets and Capsules in Korea
- Antioxidant activity of myricetin p resence of taurine
- PK/PD modeling for antiplatelet and cardiovascular effect of triflusal in human
- Characteristics of Pharmacogenomic and pharmacogenedc of 5 -FU in Koreans
- Conception and Synthesis of Aromatase Inhbitor
- Antiinflammatory effect of rotenoids from fruits of Amorpha fruticosa
- Cholinesterase inhibitory activity of oligostilbens from Vitis amurensis
- Effect of CYP2C9 polymorphism on the pharm acokinetics of lomoxicam in healthy Korean subjects
- Improved detection of microbial growth using automated culture system BacT/ALERT 3D.
- Anti-complement Activ ty of Constituents from the Leaf and Twig of Acer okamotoanum
- The reactivity of chalcone on the oxidative cyclization.
- A Study on Establishment of Assay method by HPLC of Herbal Medicinal Preparations containing Comus Fructiis.
- Inhibitory Effect of Euscaphic Acid and Tormentic acid from the Roots of Rosa nigosa on H igh Fat Die t-Induced Obesity in the Rat
- Total synthesis of Costunolide
- Synthesis of the carbocyclic phosphoramidite derivative of 2 '-deoxy- 2 '-C-p-methylcytidine
- Hepatoprotective Effects of Brassica campestris L. var. rapifera
- Inhibitory Effects of Phenolic compounds from Lysimachia clethroides DUBY on the Melanin Biosynthesis
- Determination of cytochrome P450 enzymes involved in the metabolism of rutaecarpine in human liver microsomes
- Identification of Hoelen Species in the Herbal Medicinal Products Using Molecular biological analysis Method
- Saturable Distribution of Tacrine into the Striatal Extracellular Fluid of the Rat： Evidence of Involvement of Multiple Organic Cation Transporters in the Transport
- Sesquiterpenes from Saussurea macrolepsis
- Clinical significance of CD99 downregulation and its mechanism in gastric adenocarcinoma
- Role of Translationally Controlled T\imor Protein in the Pathogenesis of Hypertension
- Point to Consider in Recombinant Products Evaluation
- Immunosuppressive Effects of Carbon Monoxide, a Gaseous Product of Heme Oxygenase-1
- Thermostability, Substrate Specificity and Transphosphatidylation of Phospholipase D from Streptomyces sp.
- Saponins Derived From Roots of Platycodon Grandiflorum Reduce Endothelial Adhesion Molecules ICAM-1 And VCAM -1
- Oral delivery of pooly water-soluble genistein incorporated in solid lipid micro/nano-spheres
- Inhibitory action of alpha-viniferin from Carex humilis on interferon-gamma-induced nitric oxide production
- Improvement of bioavailability and photostability of amlodipine using redispersible dry emulsion
- Study on the hydrolysis mechanism of PDE4D
- Determination of P lasma Tulobuterol Concentration by Gas Chromatography
- Preparative Resolution of the bevantolol Enantiomers
- Inhibitory effe t of irradiated LPS on L PS-induced endotoxemia
- Glucosylated Polypropyleneimine Dendrimer as a Novel Gene Carrier
- Prediction of Human Intestinal Permeability of Drugs from in-vitro Experiments
- Heparin, Low Molecular Weight Heparins and Analogs as Pharmaceutical Agents
- The Anti-inflammatory and Anti- nociceptive Effects of Ethyl Acetate Fraction of Cynanchi Paniculati Radix.
- Synergistic Induction of Growth Inhibition and Apoptosis in Cancer Cells by ID-6105 and Doxorubicin, Alone and in Combination with Tissue Cultured Mountain Ginseng Extract.
- Simultaneous Determination Of 16 Antiretroviral Drugs In Human Plasma For Quantitative Analysis With Liquid Chromatography-Tandem Mass Spectrometry
- Analysis of Prescribing Pattern with the Negative List Formulary System in Korea
- Efects of Six Polycyclic Aromatic Hydrocarbons on Liver and Lung Microsomal Cytochrome P450s in Rats
- Role of Early Growth Response Factor-1 and Hepatocellular Hypoxia in the Development of Chronic Liver Disease
- Inhibitory Effect of Ficus carica on the Lipid Production in Human Sebocyte Cell Line
- Identification of three plant extracts competitively inhibiting a 60 kDa membrane-associated ,Mg-dependent and neutral sphingomyelinase activity from Korea domestic natural plants
- Regulation of Tissue-Specific Gene Expression by Coordinated Changes in DNA Methylation and Histone Modifications in the Coding Region
- Qualitative Analysis o f Amitriptyline , Imipramine and their Metabolites in Blood by GC-MS
- DNA Topoisomerase II Inhibitory Activity of Procyanidin B4 from Mucuna birdwoodiana
- Antioxidant compounds from Aerial Parts of Atractylodes macrocephala .
- Preparation and Characterization of PLGA N anoparticles for Sustained Drug Delivery
- Capsaicin enhances the anticancer effect of 5-fluorouracil through peroxisome proliferatoractivated receptorg pathway in HT-29 human colon cancer cells
- Potent inhibition of human cytochrome P450 IBl by 2,2" ,4,6" -tetramethoxystilbene.
- Structure - activity Relationship of Multihydroxyursane-type Triterpenoids on the Inhibitory Effect of TPA -induced Ear Edema
- D ifferent Expressions of Platelet Glycoproteins between Catecholamine Responders and Nonresponders
- N-methyl-N-propyny l-2 -phenylethylamine, a selegiline analog attenuates MPTP-induced dopam inergic toxicity：com parison with the effects of selegiline.
- Inhibitory effects of Artemisia princeps on passive cutaneous anaphylaxis reaction
- Current development and Evaluation of Vaccine & Safety & Efficacy Evaluation of Vaccines
- Development of Vaccines to Emerging / Reemerging Virus: SARS - A Case Study
- Petrotetrayndiol A from Sponge Petrosia sp., Induces A poptosis in Human Skin Cancer Cells
- INHIBITORY ACTION OF qj-CONOTOXIN GVIA AND CELNIDIPINE ON CATECHOLAMINE SECRETION
- A linker Molecule for Regulating Inflammation and Angiogenesis
- Synthesis of New 3 -A Uylthio -6 -aminopyridazine Derivatives and Their Antihepatocarcinoma Activity
- Correlation between antioxidative and antinephrotoxic activity of (+ )-catechin-7 -0 -p -xylopyranoside under renal injury
- Formulation of Transdermal Drug Delivery Systems Containing Fentanyl
- Protein tyrosine phosphatase IB inhibitory activity of triterpenes isolated from Astilbe koreana
- Thioredoxin/TRX-Dependent Redox Regulation of Inflamamatory Process
- Anti-inflammatory Effects of Apigenin on Lipopolysaccharide-induced Activation of Microglia is M ediated by Inhibition of the NF -kB Pathway in BV -2 Cells
- Pharm acokinetics of aceclofenac and its metabolites in human
- Induction of cell cycle arrest and apoptosis mediated by xanthorrhizol in human colon cancer cells
- Development of New Histone Deacetylase Inhibitors using Chemical Genomics
- Design and Synthesis of N-Aryl-6-hydroxy-7-methoxy- 2 -chromancarboxamide Derivatives
- Molecuiar Mechanism s of Inhibitory Effects of PLG. an alkaloid from Piper longum L., on Throm bosis and Atherosclerosis D evelopment
- The Role of Epidermal Growth Factor in Enhancing Dermal Matrix Regeneration and Its Implication in Wound Contraction and Scar Formation
- Development of a Rapid HPLC Method for the Analysis of Anti-impotence Drug Analogues in Foods using a Monolithic Column
- Inhibition of Chronic Skin Inflammation by Topical Anti-inflammatory Flavonoid Preparation,Ato Formula
- Process Analytical Technology (PAT); What is PAT
- Design and Synthesis of F luorocyclopentenyl-pyrimidines as Potent Anticancer Agents
- Clotrimazole cause G1 cell cycle arrest in HT -29 human colorecta l cancer cells
- Chromatographic enantiomer separation of N-benzyloxycarbonyl amino acids and their esters on polysaccharide derived chiral stationary phases
- Honokiol protects rat hepatocytes from bile acid-induced apoptosis
- New Approach to Chiral Oxazolidin-2-one from Oxirane with Use of Chlorosulfonyl Isocyanate
- Effect of Novel Antihypertensive Drug, Fimasartan in Variety of Experimental Hypertension Model
- Analytical Method Validation and Bioavailability Study of Sodium Alendronate in Human Urine
- Strain Improvement of Streptomyces laidlogenes by Antibiotic-Biosynthesis Regulation Genes
- Suppression of Inducible Nitric Oxide Synthase Expression by L ignans from Flos Magnoliae
- Screening of pharmaceutical excipients on solubility, chemical stability and hepatic metabolism of simvastatin
- Effects of Tetrahydropapaverolin e on Dopamine Content and L-DOPA -Induced Cytotoxicity in Differentiated PC12 Cells
- Inhibitory Effects of Moraceae Extracts on Melanin Biosynthesis
- Epigenetic Modification of MGMT in Colon Cancer T issues
- Neuroprotective effect of FuUerene
- The combination of oligodeoxynucleotide and therapeutic vaccines induced by photodynamic therapy enhances antitumor immune response
- In-vitro activities of essential oils from Cnidium officinale against antibiotic-resistant bacteria
- Design, Synthesis and Cytotoxicity on the Benzonaphthofurandione and Benzofuranoquinolinedione Derivatives
- Molecular aspects of human monocytic (U 937) cells during CD29 (b l integrins) activation
- Protective roles of interleukin 6 gene in the trimethyltin-induced neurotoxicity and memory impairment.
- Chem osensitization of Human Ovarian Cancer C ells by a Recombinant Adenoviral Vecotr. AdLPCD, together with 5FC
- Efficacy and Safety Evaluation on Incrementally Modified Drug
- Anti-diabetic Effect and Mechanism s of KHP -01
- LC determination of carbamazepine in human plasma.
- Chemical and Pharmacological Profiling of Natural Products Leads and Herbal Medicines
- DNA Methyltransferase Inhibitor, 5-A zacytidine, Induced Cell Cycle A rrest and A poptosis in Human Prostate Cancer Cell lines.
- Synthesis of l-a llylthio -4 -alkylthio- 5 ,6 ,7 ,8 -tetrahydrophthalazine derivatives for hepatocarcinoma and hepatiszn
- Anti-inflammatory Activity of Trifolirhizin isolated from Methanol Extractof Sophora Flavescens Ait (the Sophorae Radix) in Experimental Animals
- Isolation of Butein from Rhus verniciflua and Synthesis of Its Derivatives with Hepatoprotective and Antioxidative Activities
- Dual Effects of Aspirin on Platelets Aggregation
- E ffect of sea cucum ber Stichopus japonicus on lipid peroxidation and antioxidant enzymes in ovariectomy
- Xanthones, Flavonoids and Secoiridoids from Halenia comiculata
- Highly Enantioselectiv e Epoxidation of 2 ,4 -Diarylenones by Using Dimeric Cinchona Phase -Transfer Catalysts: Enhancement of E nantioselectivity by Surfactants
- Effects of Candesartan on Insulin Resistance and Serum Concentration of MMP-2, MMP-9,TIMP -1, and TIMP -2 in Type - 2 Diabetic Patients with Hypertension
- TNF-a induces invasion by stimulating urokinase-type plasminogen activator and b-catenin signaling in human breast epithelial (M CF-lO A) cells through generation of reactive oxygen species
- Total Synthesis of Manzacidin B
- Hepatoprotective activity of LAB(lactobacillus acidophilus. Bifidobacterium bifidum and Streptococcus thermophilus) in Rat treated with Carbon tetrachloride and Ethanol.
- Inhibition of Lipopolysaccharide -Induced Expression of Inducible Nitric Oxide Synthase by Ethyl Acetate Fraction of Angelica Dahurica in Mouse Macrophage Cells.
- Hypoxia-Stimulated Transcriptional Activation of the eNOS Gene Is Mediated Through the Tax -Responsive E lement (TRE) in Endothelial Cells
- Microarray analyses of gene expression changes by paeoniflorin, paeonol, and albiflorin from Paeoniae Radix
- Anti-Osteoclast Therapy in Bone Disease
- The Korean Red Ginseng Extract Rescues PC12 Cells from PCB -induced Oxidative Cell Death by Activating Nrf2 and Upregulation of Heme Oxygenase-1 and y -Glutamate-Cysteine Ligase
- Determination of Zolpidem Tartrate in human plasma by HPLC with Fluorescence Detection and its application to a bioequivalence study
- A New HPLC Method to Determine Mequitazine in Pharmaceutical Preparations
- DRE-CALUX bioassay for the dioxin level inenvironm ental matrices and human blood
- Implications of Inflammatory and Oxidative Tissue Damage in Gastrointestinal Carcinogenesis
- Application of PAT in Pfizer Global Manufacturing
- Use of Single Nucleotide Polymorphism (SNP) in Toxicogenomic Research
- Patent Map of the Bioavailability Related Pharmaceutical Compositions
- In hibitory effect of alantolactone . a naturally occurring sesquitepenoid , on the growth o f human colon cancer cells
- The Effects of Aquas Extract of M.diantheraCAEMD) on Mast Cell Mediated Immediate-type Hypersensitivity.
- Inhibition of inducible nitric oxide synthase by sumaflavone isolated from Selaginella Tamariscina
- The Chracteristics of Illegal Oral Therapies for Erectile Dysfuntion in Korea.
- Case Report of Aspirin Intoxication
- Chronic toxicity of ch lorostyren es in the nematode Caenorhabditis elegans
- Protective Effect of Gisenosides for Neurotoxicity in Human Neuroblastom a SH -SY5Y Cells.
- Antimelanogenesis effect of phenolic compounds.
- Ulva lactuca Fucoidan and roles of Anti-oxidative emzyme in Ovariectom ized Rat.
- Effect of short-term , low dose aspirin supplementation on the activation of pro-inflammatory NF -kB in aged rats
- Synthesis and antifungal activity of 6-hydroxyciimolines
- Antihistamine Activities of Bradykinin Antagonists on Guinea -pig Ileum smooth muscle contraction
- Synthesis of 6 -chloroisoquinoline -5 ,8 -diones and [3 ,4-b ] phenazine- 5 .1 2 - diones and evaluation of their cytotoxicity and DNA topoisomerase inhibitory activity
- synthesis a d antifungal activity of new indole conazoles
- Regioselective and Diastereoselective Allylic Amination of Allylic Benzyl Ether using Chlorosulfonyl isocyanate： Asymmetric Total Synthesis of (2R ,5S )-Dihydroxymethyl-(3R ,4R )-dihydroxypyrrolidine
- Identification of Small Ligands that Inhibit the Interaction between Zalpha domain and Z -DN A
- Synthesis and antifungal activity of 4 ,7 -d ioxobenzo [b ]thiophenes
- Antimicrobial and antioxidative effects of Puerariae thunbergiana extractson skin microbial pathogens (II)
- Anxiolytic-like effects of Scrophularia buergeriana in mouse behavior models of anxiety
- Hair levels of cholesterol and 24s-hydroxycholesterol in patients with Alzheimer's disease using GC/MS.
- Preparation and evaluation of IL-5 antisense oligodeoxynucleotides/chitosan complexes
- Determination of Famciclovir in human plasma by high-performance liquid chromatography with ultraviolet detection
- Characterization and Lymphatic Delivery Evaluation of PEGylated Liposomes Containing Cyclosporine-A
- An Animal Model for the Inflammation-Related Colon Carcinogenesis
- Heme Oxygenase-1 in lUmors: Therapeutic Implications
- West Nile Virus: Therapeutic Strategies for Curing Diseases
- Development of Anti-aging Nutraceuticals from Nelumbo nucifera
- Authentication is the Fundamental Work for Standardization of Herbal Medicine
- Representation of Episodic Memory in the Hippocampus
- Osteoporosis and Traditional Chinese Medicine: an Animal Experiment
- Influence Of Anabasine On Catecholamine Release From The Isolated Rat Adrenal Medulla
- Vitexin Attenuates the Level of Hypoxia-Inducible Factor -la in PC12 Cells under Hypoxia
- Alteration of sphingolipid metabolism follow ing fumonisin exposure is a contributing factorfor a decreased Na/K-ATPase activity in LLC -PKl cells
- Lipiodol Solution of 188Re-HDD as a New Therapeutic Agent for Transhepatic Arterial Embolization in Liver Cancer
- Anti-oxidant Activity o f Pimica granatum Extracts ( I )
- Ultraviolet B Induces NF -kB Activation and Cyclooxygenase -2 Expression in Hairless Mouse Skin: Role of IkB K inase-p
- The Effects of chitosan oligosaccharide and squalen on mouse kidney about Candida albicans infection.
- HDAC inhibitors may sustain the self-renewal of mESCs in hypoxic condition by activation of LIF -Stat3 signaling
- 3D -QSAR study of HLE Inhibitory F lavonoids
- Effect of vitamin C on pre - osteoclast and osteoblast differentiation
- Analysis of Arbutin in Whitening Cosmetics
- Formulation of Transdermal Patch System Containing Tulobuterol
- Development of analytical method of Preservatives in oral rinse
- Modulation of Protein Aggregation at Liquid/Liquid Interface by Surfactants
- Bioeqiiivalence study of Fluoxetine HCl 20mg in capsule and tablet formulation.
- Enhanced bioavailability of tamoxifen after oral administration of tamoxifen with quercetin in rats
- Bioequivalence of Yutanal Capsule to Hamal Capsule (Tamsulosin HCl 0.2 mg)
- Factors A ffecting the Apparent Clearance of Tacrolim us in Korean Adult Liver Transplant Patients
- Anti Hepatitis B Therapy
- Induction of Heme oxygenase-1 and Overproduction of Carbon Monoxide Protect Cells from Apoptosis Caused by Peroxynitrite
- Injectable Polyphosphazene gels for the Local Drug Delivery
- Revised Provision for Drug Equivalence
- Biopharmaceutical Application of in situ Polymer Gel
- Combinatorial Effect of 5 -FU and Epigenetic Silencing Repressors in Huanm Colorectal Cancer Cells.
- Analytical Chemometrics for Process Analytical Technology
- Long-functioning cell therapy for treating d iab etes m ellitu s： 1 year study
- Interferon-Y Is Partly Involved in the Neuroprotective Mechanisms of Dietary Restriction.
- Apoptosis-induced cell growth inhibitory effects of a novel compound, AS4O6 in a cervical cancer cell line, SiHa in vitro
- KHUR-12 is a prominent anxiolytic agents.
- Multiplexed liquid assay system profiling for early detection of ovarian cancer
- Synthesis of Seleno-epigallocatechin-3-gallate
- Identification of system ic cell-cycle regulation by Apicindin, a histone deacetylase inhibitor in breast cancer cells through large-scale data analysis of gene expression profiling
- Development and validation of a new liquid chromatographic method with fluorescence detection for gemfibrozil analysis in human plasma
- Induction of GO/Gl cell cycle arrest by 3 -hydroxy -5 -benzoyl-trans -stilbene in HCT 116 human colon cancer cells
- Fenofibrate, an Antihyperlipidaemic Agent, Inhibits Platelet A ggregation and Proliferation of Rat Aortic Vascular Smooth Muscle Cells
- Mortality Effectin C57BL/6 Mouse Bearing Skin Cancer with Boron Compounds and Thermal Neutron Irradiation
- cis -9 ,trans-11-Conjugated linoleic acid down -regulates phorbol ester -induced COX -2 ex p ressio n in h airless m ou se skin： NF -kB and MAPKs as potential targets
- Cytokine Expressions of the Lectin from Serrognathus platymelus castanicolor.
- Hmnulone inhibits expression of COX-2 in phorbol ester -treated mouse skin by blocking activation of IkB K inase and MAPKs
- Effect of daidzein and gen istein on the antioxidant enzym e system in CHO cells.
- Electrospun PLLA-Chitossin Composite Nanofibrous Membrane for Guided Tissue Regeneration
- Total Synthesis of (+ )-Lactacystin
- Nitric Oxide Inhibitory Activities of seven Phenolic Compounds from the fruits of Actinidia arguta
- Ikaros. Transcription Factor, R egulates inducible Nitric Oxide Synthase Gene Expression through Chromatin Remodeling
- Activation of Neuroglia in the CNS Diseases
- The Wnt/P-Catenin and Ras-ERK Pahtway Interact in Cellular Transformaton
- Antidiabetic activity of Grape-Ginsengin Streptozotocin -induced diabeticrats
- The generation of soluble RANK protein using mammalian cell culture system
- Inhibitory effect of benzoxathiolone LYR -64 on expression of inflammatory mediators in LPS -stimulated macrophages RAW 264 .7
- 15 -Deoxy-A 12,14-Prostaglandin J2 Upregulates Heme Oxygenase-1 and VEGF through A ctivation of NF -E 2 -Related Factor 2 (Nrf2) in Human Breast Cancer Cells
- Enhanced Absorption after Oral Administration of Insulin
- Effect of Verapamil on the Modulation of Multi-drug Resistance and Intracellular Accumulation of a Novel Anthracycline in Hepatocarcinoma Cell Lines.
- A ntiplatelet Activity of 15 ,16 - dihydrotanshinone I. One of the Major Ingredients of Salviae Miltiorrhiza Bunge (Dansham ), and its Possible Mechanism s of Action
- Inhibitory Effect of Phthalates on Tamoxifen-induced Apoptosis
- Simultaneous Chiral Separation of Multiple p-Blockers by Capillary Electrophoresis in Reversed Polarity Mode
- Structure-activity relationship of indirubin derivatives on HL -6 0 leukemia cell differentiation
- Characterization of Cytochrome P 450 Enzymes and -Glycoprotein Involved in the Metabolism and Transport of a New Anti-an giogen ic Agent KR -31831
- Simultaneous analysis of indoloquinazoline and quinolone alkaloids in Evodiae Fructus by highperformance liquid chromatography^lectrospray tandem mass spectrometry
- Phospholipase D1 and 2 are regulated by serin e/threonine protein k inases in RBL-2H3 mast cells
- Gas Chromatographic Profiling Analysis of Catecholamine Neurotransmitters and Polyamines for Clinical Applications to Neurological Disorders
- Determ ination of Doxazosin in human plasma by h igh-perform ance liquid chrom atography with FLD detection
- A novel arsenic compound, As406 attenuates 3 -methylcholanthrene toxicity in human keratin ocytes by decreasin gcytochrome P4501A 1 expression
- Redox-Sensitive Transcription Factors in Cellular Defense Against Proinflammatory and Prooxidative Injuries
- The Shigella Flexneri Effector OspG Interferes with Innate Immune Responses by Targeting Ubiquitin-Conjugating Enzymes
- Differential Genomic Responses to Hypoxic Preconditioning and Hypoxic-ischemic Insult in the N eonatal Rat Brain： Identification of Potential Neuroprotective Candidates for Ischemic Stroke
- Qualitative estimation of major constituents of Sopung-San using U V -fingerprint and ES -LC -MS -MS
- Inhibition of Inflammatory Response by CBPharm -001 in UVB -irradiated H uman Fibroblast Cells and Lipopolysaccharide -induced RAW 264.7 Cells.
- Study on the Current Status and Future Improvement of Pharmaceutical Industry—Based Medical Information in Korea
- Comparative enantiomer separation for N-FMOC protected amino acids and their esters on immobilized and coated type chiral stationary phases derived from amylose tris(3,5- dimethylphenylcarbamate)
- Molecular modeling of novel human topoisomerase I inhibitors
- Current Status of Drug Master Files (DMF)
- In vitro Studies on the Immunosuppressive Mechanism of Recom binant CTLA4Ig from Transgenic Rice Cells
- Folate-conjugated heparin-lithocholic acid derivates induce apoptosis in human oral carcinoma KB cells
- Effect of Catalpalactone on Dopamine Content and L -DOPA -Induced Cytotoxicity in PC12 Cells
- Depurination reaction of adenin e-based nucleoside and calf-thymiis DNA with 2-bromopropane at physiological condition, and an alysis of the depurinated products using HPLC and LC/MS/MS
- Macrophage-colony Stimulating Factor Enhances MHC -restricted Presen tation of Exogenous Antigen in DC2.4 and BM -derived Dendritic Cells
- Role of glutathione peroxid ase in the neurotoxicity and dependence induced by methamphetamine.
- Induction of phase II enzyme gene expression by zerumbone derivatives in Hepalclc7 cells
- Studies on the evaluation of efficacy of functional cosmetics-E fficacy evaluation of the w hitening cosmetics using cell signalling
- L iposome - encapsulated melatonin atteenuates kainate -induced neurotoxicity via activation of melatonin MT2 receptor in mice
- Neuroprotective effect of meso-dihydroguaiaretic acid on staurosporine induced neurotoxicity in primary rat cortical cells
- Flexible docking of inhibitors into dihydrofolate reductase using QXP and Flex iDock
- Inhibitory mechanism of benzoxathiolone LYR-64 on iNOS expressionin IFN -gamma-stimulated macrophages RAW 264 .7
- The Methanol Extract from Artemisia Asiatic Naskapi Induces Gi Phase Arrest in A 172 Human Glioma Cells
- Bioinformatic Properties of the Earthworm Eisenia fetida derived Lumbrokinase 1
- A nticancer Activities and Structure-Activity Relationships of Novel Antimicrobial Undecapeptides Derived from Gaegurin 5
- Stilbenoid-induced Apoptosis Is M ediated by p38 MAPK and PI3K/Akt Pathway.
- Protective effect of the extract of Wasabia japonica on oxidative stress induced cell death
- A Famesyl Protein Transferase Inhibitory Compound from Centipeda minima
- Synthesis of Diacetoxy Acetal Derivatives of Santonin and Their Enhancing Effects on HL-60 Leukemia Cell Differentiation
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