학술논문
Pharmacokinetic and PK/PD modeling of dihydropyridine calcium channel blocking agents in cardiovascular effect.
이용수 0
- 영문명
- 발행기관
- 대한약학회
- 저자명
- YUN Min-Hyuk YUN Hwi-Yeol KANG Won Ku KWON Kwang-il
- 간행물 정보
- 『추계총회 및 학술대회』(2005년) vol.2, 530~530쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2005.11.30
무료
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
영문 초록
목차
키워드
해당간행물 수록 논문
- Clinical Trials ; Know What the KFDA Wants
- Analysis of ginsenosides of black ginseng
- Discovery of Novel Protein Tyrosine Phosphatase 1B (PTP1B ) Inhibitors by Structure - Based Virtual Screening
- Control of xenogeneic immune responses via inhibition of NK cell funtion.
- Wogonin inhib its cytokineproduction and cell migration in microglial cells via N F - kB, not cAMP,dependent pathways
- The Analysis of Genome-Wide Expression Array for the Efficacy and Toxicity Test
- Evaluation of Tumour Necrosis Factor Cytotoxicity Using the AlamarBlue Assay
- Synthesis of Poly Heterocyclic Compounds and Evaluation of Inhibitory Activities on Topoisomerase 1 &II and Antitumor Cytotoxicity
- Stereoselective synthesis of (E )-and (Z )-enol ether possessing allylic amino group ：Application to the synthesis of p -amino a -substituted acid derivatives.
- The Pungency of Garlic: Activation of TRPA l and TRPV l in Response to Allicin.
- Synthesis of Tyrosinase In hibitory Kojic Acid Derivative
- Continentalic acid from Aralia continentalis as an active antibacterial agent againt Methicilline-resistant Staphylococcus aureus
- Pharmacokinetic-pharmacodynamic model of direct thrombin inhibitor, argatroban, in predicting concentration-effect relationship in rats
- Anti-oxidative effect of Leucocyanidine and herbal extracts in ethanol-fed rats
- Liquid Chromatographic-Tandem Mass Spectrometric Determination of Itraconazole
- Hydroquinone suppresses macrophage-mediated immune responses
- Pharmacokinetic and Pharmacodynamic Analysis of CNS Drugs
- Inhibition of Lipopolysaccharide-induced Expression of iNOS and COX -2 by Ethanol Extract from G leditsia sin en sis via Suppression of Nuclear Factor-icB Activation in RAW 264 .7 Macrophage Cells
- Chronic E xposure to Smoking Extracts Decreases Nitric Oxide Production in Endothelial Cells：Evidence for involvement of cyclic AMP and phosphodiesterase 4C
- Topical delivery of low molecular weight heparin with surface-charged flexible liposomes
- Curcumin induces ubiquitination of c -ErbB2 /Neu via the chaperone - dependent E3 ubiquitinlig ase CHIP An implication in down -regulation of ErbB2 activity by curcumin
- From Genes to Drug: Osteoporesis
- Oxidized peroxiredoxin -3 as a protein biomarker for cadmium - and ceramid e-in duced toxicity in human brain cells through display proteomic analysis
- Co-transfection of smad3 and IL-13 antisense oligonucleotides for the treatment of skin fibrosis using solid lipid nanoparticles
- Oral Absorption Enhancement of Pranlukast Hemihydrate, Poorly Water Soluble Drug
- Exposure to extrem ely low frequency m agnetic field enhances locom otor activity and fosrelated antigen im m im oreactivity via activation o f dopamine D1 recep tor in mice.
- Development of coated ibuprofen-loaded gelatin microcapsule as sustained release oral delivery with enhanced bioavailability
- Discovery of KR-33028, a highly selective sod ium-hydrogen exchanger subtype 1(NHE-1 ) inhibitor
- Effects of Korean Mistletoe Lectin on Proliferation and Cytokine Expression in Human T -Cells and Murine Splenocytes
- A lteration of Gene Expression after Cadmium Exposure in A 549 Human Lung Carcinoma Cell Line
- Transcriptional configuration of ENPP2 (Autotaxiii/lysoPLD) in breast cancer cells by using DNA m icroarrays
- Antitumor effect of thio-Cl-IB -MECA in HCT 116 -xenograft nude mouse model
- Highly Enantioselective Synthesis of (2S)-Q -(Hydroxymethyl)-glutamic Acid via Phase -transfer Cataly tic Michael Reaction
- cGM P/protein kinase G-dependent inhibition of TRPV l activity in rat sensory neurons
- Anti-Prostate Cancer Effect of Oxypeucedanin from Angelica koreana
- Inhibitory Effects of Saponins Derived from Roots of Platycodon Grandiflorum on NNK-Induced Lung Tumorigenesis in A /J M ice
- Evaluation of Chondroitin Sulfate in Shark Cartilage Powder as a Dietary Supplement
- Monoamine Oxidase Inhibitory Quinolone Alkaloids from the Fruits of Evodia rutaecarpa
- Current Efforts to Overcome the Barriers to Oral Protein Delivery
- E stablishment of Reporter Cell L ines for Assessment of Carcinogenicity of Toxic Chemicals
- Novel Nano-biomaterials for Protein and Gene Delivery
- Anti-convulsive effects o f Wogonin and Baicalein in ICR Mice
- Synthesis and High Binding Affinity of 3' -Ureidoadenosines at the Mutant A3 Adenosine Receptors
- Patent Map of Pharmaceutical Composition for Natural Products
- Anti-proliferative effects of lignan components in the extract from the aerial part of Saururus chinensis on human tumor cell lines
- Roles of zHyrac in the development of zebrafish nervous system
- PAT - A European Academic 후s Perspective
- Effect of Vehicles and Penetration Enhancers on the In Vitro Percutaneous Absorption of Alendronate through Hairless Mouse Skin
- PEGylated Nano-hybrid Adenovirus: Retargeting A denovirus to Tumor Cells
- Regulation and Functional Role of 58kDa CRMP-2 Expressed in PC12 Cells during Ischemia
- Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the determination of levofloxacin in human plasma
- E ffect of DA -8159 , a PDE5 Inhibitor, on Intraurethral Pressure in Steroid Induced Benign Prostatic Hyperpla sia Rats
- Potent Inhibition of P-glycoprotein Mediated Multi-drug Resistance by a Natually Occurring Phenylbutenioid Dimmer
- Gelatin-doxorubicin nanoparticle and PEGylated gelatin -doxorubicin nanoparticle as an effective cancer therapeutics
- Application of Expression Genomics into Toxicology for Discriminating the Molecular Basis of Toxicity and Toxicant-related Disease
- Cytotoxic constituents from Hypsizigus marmoreus
- Anti-inflammatory Activity of 20(S )-Protopanaxadiol: Enhanced Hem e Oxygenase 1 Expression in RAW 264 .7 Cells
- Geneticin Inhibits Ischemia-induced Apoptosis and Prevents Myocardial and Cerebral Ischemia /Reperfusion Injury
- Induction of G 2/M phase cell cycle arrest by an adenosine analog , thio-Cl-IB-MECA , in human colon cancer cells
- Diastereoselective Aminadon with Use of Chlorosulfonyl Isocyanate and its application to the Synthesis of (± )-4-epi- Cytoxazone
- Combined effect of heparin -Deoxycholic acid (heparin-DOCA) derivative and doxorubicin on apoptosis and tumor grow th inhibition in Squam ous cell carcinom a (SCC)and B16F10 melanoma
- Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via su p p re ssio n of NF - kB and Akt activation
- Production of NO. TNF -a and IL-6 by Squaiene, A lkoxy Gycerol, Batyl and Chimyl solutions in Raw 264.7 macrophage cells
- Identification of Genes that are Induced after Form aldehyde Exposure by Suppression Subtractive Hybridization
- The role of dynorphin gene in the methamphetamine - induced behavioral side effect and dopam inergic to xicity in mice.
- Flavonoid glycosides from Cephalotaxuskoreana
- Solid state characterization of fluconazole polym orphs prepared by the SEDS process using Solid -state carbon -13 cross-polarization magic angle spinning (CP/MAS) Nuclear Magnetic Resonance spectroscopy
- Bioactive constituents from the leaves of Zanthoxylum schinifolium .
- National Compound Repository System
- Neuroprotective Eeffects of Amentoflavone in Neonatal Hypoxic-ischemic Brain Injury are M ediated by Direct Blockade of Apoptosis and Necrosis and by Inhibition of Inflammatory A ctivation of Microglia
- Study of the Current Situation on the Production and Distribution of Sm all-Packaged Reimbiirsable Drugs
- Gomisin A significantly improved scopolamine-induced memory impairment in mice
- Pharmdb:A Database for the Prediction of Pharmacological Targets based on an Integrated Drug-Target Network Analysis
- The Dysfunction of Blood-Brain Barrier in the Cerebral Vascular Dementia
- Alteration in the Expression of Heterotrimeric G P rotein P4 Subunit in Rat Brain by Age
- Evaluation of the Estrogenic Activity of Oriental Plants with Implications for its Role on Vascular Systems
- Study on the structure-function relationship of several Helicob acter pylori proteins
- Systemic Hypertension in Transgenic M ice Overexpressing Translationally Controlled Tumor Protein
- Lysophosphaddic acid -induced VEGF expression requires PI3-k inase/A k t/mT0R and p42/p44 MAP kinase pathways
- Anti-Oxidant and Nitric Oxide Production Inhibitory Activities of Extracts from Tricholoma matsutake Sing of Four Grades.
- Pyrrole Alkaloid and Megastigmane Derivatives from Non- polar Fraction of Opuntia ficus-indica var. saboten
- A ntioxidant compounds from Aerial Parts of Scutellaria baicalensis
- Vasorelaxant activity of the rhizome extract of Alpinia officinalum on the contractility of rat aorta
- Antioxidant activity o f sea cucumber Stichopus japonicus
- dbPIATDatabase of Proteome Information of Aged animal model's Tissues
- Synthetic Bile Acids: Novel Modulators of the Cell Cycle and Mediators of Apoptosis in Several Human Cancer Cells in V itro and in Vivo
- Anti-allergic Activities of Bradykinin Antagonists： Their In hibitory Effects on Histamine Release from RBL -2H3 Cells.
- Ontogeny of oxidative stress in the genetically epilepsy-prone rats: roles of the adenosine A1 receptor and glutathione peroxidase.
- Involvem ent of Dopamine and NMDA Receptor Systems in Inhibitory Effects of Berberine on Morphine R einforcem ent and Analgesic Tolerance
- Antitumor Activity of Pulsatilla koreana Saponins and Their Structure -Activity Relationship
- Free radical scavenging activities of Fagaceae (Quercus) plant extracts
- Involvem ent of phosphatidyl inositol 3 kinase and Akt in regulation of muscarinic receptorm ediated sAPP release and CCE in SH-SY5Y cells
- ORAL DELIVERY OF LMWH DERIVATIVES USING DMSO FORMULATION IN VIVO
- Quercetinis a Potent Inhibitor of HIF -prolyl hydroxylase ： Im plication in Ulcer Healing Effect of Quercetin in Experimental Colitis
- Asymmetric Synthes s of Deoxymaiinojirimycin via Regioselective and Diastereoselective A m ination w ith Use of Chlorosulfonyl Isocyanate
- Relationship between compound substructure and biological activity： construction of focused library
- Immunostimulating activity effect of water extract of Acanthopanax Refinerve Nakai leaf in human peripheral blood mononuclear cells
- Whitening effect of silk powder
- Induction of Growth Hormone (GH) Release by K OM -12
- Phytochemical analysis of phenolic compounds from Panax ginseng
- Biological Activity and Pharmacokinetics of PEGylated Somatostatin Analogues
- Antioxidant compounds from Leonuri herba
- Activities of the Essential Oils Fraction in the Leaves of Coreandrum sativum against Streptococcus
- The Effect of l-Furan-2-yl-3-Pyridine-2-yl-Propenone on Pharmacokinetic Parameters of Theophylline
- Identification of Gene Expression Signature for Molecular Classification in Human Leukemia
- Accelerated wound healing by in vivo application of smadS antisense oligonucleotides impregnated chitosan/alginate polyelectrolyte complex
- Chemical analysis of Anethi fructus for quality control by gas chromatography
- Anti-Complementary Activity of Ursane-Type Triterpenoids from Weigela subsessilis
- A Study on the Diagnostic Method for Galactosemia by IC-PAD
- T h e effect of meso-d ihydroguaiaretic acid on the expression of matrix metalloproteinase - 2, 9 cause by ultraviolet irradiated cultured human keratinocyte cells (HaCaT)
- Effects of KIOM -79 on Prevention of Diabetic Nephropathy in the Goto-Kakizaki rat . a Model of lean Type 2 D iabetes
- Design of Apolipoprotein A l-mimetic peptides with enhanced antioxidant actions
- Heral Extract In duces Rat Growth Hormone in Rat Pituitary Cells and Prevents Bone Loss in Ovariectomized (OVX) Rats
- Regulation of Synaptogenesis by PSD-95
- Effect fCYP2C9 polymorphism on the pharmacokinetics of irbesartan in healthy Korean subjects
- Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel
- Inhibitors from Alpinia Officinarum on LPS -induced Nitric Oxide Production in Macrophages ：Structural Requirements of Diaryheptanoids for the Activity
- Butein decreases oxidative stress and JNK activation in GCDC-induced primary rat hepatocytes.
- Effects of Sanguiin H -6 from Rubus coreanus on VEGF Binding to VEGF Receptor and Endothelial Cell Growth
- SB Inhibits Immunostimulatory Function of Dendritic Cells： MAPKs and translocation of N F-kB as potential targets
- Benzoxathiolone LYR -64 inhibits NF-kB activation via IKK complexin LPS -stimuated macrophages RAW 264 .7
- Multiple Conformations in the Ligand-Binding Site of the Yeast Nuclear Pore Targeting Domain of NUP116P
- Ulva lactuca Fucoidan and its Lipid m etabolism on Disfunction of Ovariectom ized rats,
- Antifungal Activity of Chlororinated bibenzyl compound on the Dermatophytic Fungus Trichophyton mentagrophytes
- Determination of Doxazosin in Human Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry
- Effect of CYP2C9 polym orphism on the pharm acokinetics of candesartan in healthy Korean subjects
- Enhanced intestinal absorption of biotinylated glucagon-like peptide-1 (7-36)
- Concentrations of organophosphoms insecticides in postmortem blood or specimens in the fatalities of Jeollanam-Do, JeoUabuk-Do and Jeju-Do of Korea from 1997. 7. to 2005. 6 (n=44)
- A Sensitive determination of fluconazole in human plasma by high-performance liquid chromatography with ultraviolet (HPLC-UV) detection： Application to comparative bioavailability study in Korean men.
- Isolation and Structural Identification of Minor Constituents from Sasa borealis
- Effect of Eupatilin on Cell Viability and Lytic Gene Expression in Epstein -Barr Virus Positive Gastric Carcinoma Cells
- Development and Validation of a Rapid HPLC-FLD Method for the Determination of Penciclovir in Plasma； Application to a Bioequivalence Study
- Effects of ginsenoside Rbl on brain cholesterol and 24S-hydroxycholesterol levels in immobilization stressed mouse
- Formulation of Transdermal Drug Delivery Systems Containing Ondansetron
- Pharmacokinetics of cefroxadine in Korean healthy subjects
- Establishment of rapid analysis methods for tetraconazole, flxiazifop-p-butyl, and fluoroimide residues in agricultural products with a GC
- T h e studies on the effect of DULAC™ on the intestinal and immune system o f rats
- Classification of WooHwangChongShimWon solution products based on musk substitutes by using near infrared transmittance spectroscopy and principal component analysis
- Oral Drug Delivery: Scientific Challenges and Product Development
- In Vitro and In V ivo Efficacy of a New Fluoronaphthyridone, DW -224a, against Streptococcus pneumoniae.
- Gas Chromatographic Profiling Analysis of Amino Acid Neurotransmitters and Acidic Metabolites of Catecholamines for Clinical Applications to Neurological Disorders
- Protein -bound Polysaccharide as Immuostimiilator for Cacner Therapy： Antitumor and Antimetastatic Effect by T- cell, NK - cell and Macrophage
- Neurochemical Regulation of Complex Behaviors: Conceptual Perspective
- Bioequivalence Evaluation of Lomoxicam 4 mg Tablets in Healthy Male Korean Volunteers
- Effect of gamma irradiated phytic acid on the function of immune cells
- Purification and Prophylactic Efficacy Study of Human Papillomavirus-like Particle Expressing HPV16L1 Capsid Protein
- Licensure of Biological Products in KFDA
- Synthesis of Methyl or Chloro-Containing T riaromatic-Substituted 2 ,4 ,6 -Pyridine Derivatives and Evaluation of Their Antitumor Activities
- Dopamine release in PC12 Cells is mediated by Ca -dependent production of ceramide via sphingomyelin pathway
- P-glycoprotein Inhibitory Activity of Tricin in Human Breast Cancer Cells
- The Mechanism of Sphingosine 1- phosphate -induced Extracellular Signal Regulated Kinase Activation in Cultured Feline Esophageal Smooth Muscle Cells
- Effects of a-Tocopherol and Deferoxamine on Methamphetamine-Induced Neurotoxicity in Rats
- Translationally Controlled Tumor Protein Interacts with Sorting Nexin 6
- Carrier-Mediated Absorption of Ketoprofen in Rats
- Effects of physicochemical parameters on skin permeation by Ultrasound
- Analysis of alendronate in human urine using high-performance liquid chromatography with column-switching system
- Antiinflammatory Effect of Chunghyuldan in Lipopolysaccharide-induced BV -2 Cells
- Polymorphic Transformation of DA-6034
- Identification of mammalian cell genotoxin s in respirable particulate matters (PM 2.5) in urban area by bioassa y -directed fractionation
- D eadenylation of adenine-based nucleoside with 2-iodopropane, brom oethane and 2 .3 -dibrom opropene at p hysiological condition, and analysis of the depurinated products using HPLC and LC/MS/MS
- Hepatotoxic and Immunotoxic Effects o f 1 -Bromopropane and its Conjugation with Glutathione in Female BALB/c Mice
- Upregulation o f Cellular N F-kappaB A ctivity by NMU and NEU in Murine Macrophages is via Protein Kinase C -Mediated Pathway
- The Role of Toxicogenomics in Drug Discovery & Development
- Control of Osteoclasts as a Therapeutic Approach to Osteoporosis and Other Bone Diseases
- Antidepressant Drug Evaluation Using in vivo Screening Tool
- Anti-diabetic Effect and Mechanisms of KHP -02
- Mitochondrial Mechanisms of Tetrahydrobiopterin -Induced Dopaminergic Cell Death
- A nti-Hepatic Cirrhosis E ffects of Schizandrin, Glycyrrhizinic acid and Wogonin on T A A -induced Hepatic Cirrhosis in Primary Cultured Rat Hepatocyte and Stellate Cell
- Elucidation of anti-diabetic mechanism of Compoud K
- Effects f HDAC Inhibitors on Huntingtin Aggregation and Cytotoxicity in PC12 Cells for Huntington's Disease Model
- Structural Characterization of Urease Accessory Proteins
- Quantitative analysis comparison of pulegone content Korean and Chinese Schizonepeta tenuifolia
- Action of Artemisia Iwayomogi on M ast Cell-Mediated Allergy Model
- Determination of Byak-angelicin, Imperatorin, Oxypeucedanin and Isoimperatorin in Angelica Dahurica Root
- Development of New Fluorescence Analysis Method of Sugar
- Brazilin induces quinine reductase and heme oxygenase- 1 expression in Hepalclc7 cells
- Comparative chiral discriinination studies of (+ )-(18-crow n-6)-2,3,11,12-tetracarboxylic acid as a chiral selector by NMR spectroscopy and high-performance liquid chromatography
- Chiral purity test of bevantolol by capillary electrophoresis
- Protective Effect of Acanthopanax koreaniim Extract against Oxidative stress
- Study on encapsulation efficiency of the pegylated liposome carrying pCEP4 clone 790 DNA
- In vitro permeation and retention studies of 5-aminolevulinic acid based on the UDL for photodynamic therapy
- Investigation on the contrast agent for the liver targetdns in MRI
- Deformable Liposomes for Skin Delivery of Arbutin
- Defect of Toll-like receptor- mediated IL -8 signaling in human epithelial cells infected with Vibrio vulnificus mutants
- Preparation and Characterization of Paclitaxel-loaded PLGA Microspheres
- Comparison of Pharmacokinetics of Loxoprofen and its Active Metabolites after an Intravenous, Intramuscular and Oral Administration of Loxoprofen in Rats • Evidence for Extrahepatic Metabolism
- Bioequivalence of Glazid Tablet to Diamiclon Tablet (Gliclazid 80 mg) by Liquid Chromatography/Electrospray Tandem Mass Spectrometry
- Cost-Effectiveness Analysis of Treatment Options for Methotrexate -Resistant Rheumatoid Arthritis in Korea
- A Tetranor-cycloartane Triterpene Glycoside from Cimicifuga Rhizome and anti-complement Activity
- Effects of Various Surfactants on Solubilization and Dissolution of Poorly Water Soluble Acidic Drugs
- Memory Enhancing Effect of Essential Oil of The Needle of Abies koreana on Scopolamine Induced Amnesia in Mice
- Protective effects of natural com pounds, madecassoside and madecassic acid, on cisplatin-induced oxidative stress via MAPK activation and Nrf2
- Bisphenol A (BPA) Induces Apoptosis in Mouse Hippocampal (HT -22 ) Cell.
- Effects of chitosan oligosaccharide on the Candida albicans induced secretion of TNF -a and IL-6 in Raw 264 .7 cells
- HIL(hiuman interleukin )-6 inhibitory compounds from Selaginella tamariscina (Beauv.) Spring
- Enhanced bioavailability of itraconazole with a new self-emulsifying formulation in healthy volunteers： effects of food and dose on the oral absorption
- Dosage form design and evaluation of polyene antibiotic, amphotericin B for oral administration.
- Antifungal activity of (- )- ent- costimolide on the dermatophytic fungus Thichophyton mentagrophytes
- Validation of L-camitine in biological samples using HPLC with fluorescent detection via dehvatization techniques
- Inhibition of D acylglycerol Acyltransferase by chalcon , kuraridin from Sophora flavescens
- Lactic Acid Fermentation of Dioscorea Rhizome
- Signaling Molecules Mediating the Toxicity of 6-Hydroxydopamine in S K-N -SH Human Neuroblastoma Cells
- Regulation of human NK cells activation and function through 2B 4/CD 48 homotypic interaction
- Crystal structure of YTK -1 (C16H20O6)
- Extract of Punica granatum Inhibits Skin Photoaging Induced by UVB Irradiation
- 3 -0 -A cetyIated Catechin as A Potent Competitive Inhibitor o f Hepatic Microsomal CYPlA l
- The Modulation of Toll-Like Receptors: A New Gate to Control Chronic Inflammatory Diseases
- From Synthesis to Breast Cancer; the Multifaceted Roles of Organic Sulfates
- The Role of Sphingom yelinases on Fas-mediated Apoptosis in Human Jurkat T-Lymphocytes.
- A pplication of Proteomic and Bioinformatic Techniques to Aging Research
- Fast HPLC Method for Simultaneous Determination of Bioactive Components from Paeoniae Radix
- Diterpenes from Aralia continentalis
- Structural Studies of the Human Protein Tyrosine Phosphatase Family and Their Application in Drug Design
- Kinetic Analysis of the Hepatic Transport of ID-6105, a Novel Anticancer Agent, by Sandwich-Cultured Rat Hepatocytes
- Antimicrobial activity of selected Korean medicinal plants and herbal product
- Orthogonal A rray Design in Optimizing the Extraction Efficiency of Active Constituents from Jakyak -Gamcho Tang
- Effect of Itraconazole, a Cytochrome P450 3A inhibitor, on the Plaszna Concentrations of Risperidone and 9-Hydroxyrisperidone in Schizophrenic Patients
- Preparation and Evaluation of Controlled Release of Tamsulosin hydrochloride from Alginate Beads reinforced with Waxy Materials
- Homology Modeling of Melanin-concentrating Hormone Receptor 1 and Ligand Complexes for Successful Computational Screening
- Identification and Characterization of N ovel HDAC Isofonn -Selective Inhibitors for Development of Anti-cancer Agent
- Immunosuppressive Properties of RP 10356 Isolated from Hahella chejuensis in Peritoneal Macrophages
- Anti-Allergic Effect of Dracocephalum argimense on Mast Cell-Mediated Allergy Model
- A New Lavandulylated Flavonoid from Sophora flavescens Roots
- Study on the identification methods using IR-spectormetry for K.P.-drugs
- Anti-inflammatory effect of artemisolide on LPS-inducible inflammatory mediators in macrophages
- Application and Validation of a Liquid Chromatographic Tandem Mass Spectrometric Method for the Determination of Clopidogrel in Human Plasma
- Chemopreventive Effects of Curcumin on Azoxymethane-Initiated and Dextran Sulfate Sodium-Promoted Mouse Colon Carcinogenesis
- M olecular Mechanisms Underlying the Neuroprotective Effects of Escule tin on Oxidative Stress - induced Apoptosis in SH -SY5Y Cells
- Regulation of MMP-2 Expression by Gai2 ： Implication for Invasive Phenotype in Human Breast Epithelial Cells
- Inhibition o f tumor metastasis and tumor growth by a fermented extract of Korean m stletoe
- Immunomodulatory effect of the water extracts of Acanthopanax Rufinerve Nakai. on the production of Interleukin-2(IL - 2) and Interferon-Y (IFN -y) in PBMC. ,
- Bioanalytical Method validation of Testosterone in Rat Serum by Ligand-binding Assay
- The practical validation guidelines for performance verification of UV-VIS spectrophotometer
- Regulatory Expectation of Investigational New Drug Application (IND) in Cell and Gene Therapy Products
- Short-term feeding of baicalin inhibits age -associate dNF-kB activation
- Isomer docking studies of captoprils into mono-zinc carbapenemase and phosphoxiate monoesters into serin e beta -lactamase
- Determination of a Rapid and Sensitive Method for the Quantitation of Malachite green and Leuco-malachite green by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry(UPLC-MS/MS)
- A study on the standardization of Dipsaci Radix.
- Kainate-induced seizure intensity is not consistent with wet dog shake be aviours in the genetically epilepsy-prone rat： involvement of altered serotonergic system .
- Studies on the Standardization of Processed Coptidis Rhizoma Mixed with Wine
- Immune Responses of Peptide Vaccine against Systemic Infection due to Streptococcus Pneumoniae.
- In Vitro Dissolution: Current Issues and in Vivo Relevance.
- Study on a cytosolic, magnesium -independent and neutral sphingom yelinase in bovine brain
- Determination of proteins in infant formula by high-performance liquid chromatographyelectrosprayelectrospray tandem mass spectrometry
- The effects of membrane phospholipids headgroups on the pore-forming activity of L isteriolysin 0
- Lactic Acid Bacteria Increases Antihyperlipidem ic Effect of Crocin Isolated from the Fructus of Gardenia jasminoides
- A dhesion of osteoblast on FGF and Fibronectin-FG F fusion proteins absorbed chitosan surface
- Bovine lactoferrin suppresses ConA -induced T cell activation in mice
- Study of an organic fraction from Taraxacum officinale with cytotoxic activity on the thymocytes in culture
- The modification process for production of Sachromyces cerevisiae (KCTC-1199) containing Bio-germanium, Geranti Bio-Ge Yeast
- Simultaneous determination of simvastatin and simvastatin acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry
- Instilin -secretion activity of 3 - 0 - methylursolate in rat pancreatic islet cells
- Degradable PEG Nanogels for Cytosol-specific Release of Plasmid DNA
- Aberrant regulation of histone deacetylase 2 and Wnt/B-catenin signaling are distinct oncogenic event in human hepatocelluar carcinoma
- Hypoxia Influences S teady-State Level of ER mRNA in MCF -7 Cell
- Proliferative activity and protective effect of Kobophenol A on Osteobla st-like MG -63 cells
- Acute Oral Toxicides of Ethanol Extraction from Cordyceps pruinosa
- Process Understanding in Pharmaceutical Companies
- Enhanced nasal delivery of interleukin (IL)-4 antisense oligonucleotides (AS-ODN)
- Neuroprotective Effects of Rutaecarpine against H202~induced Oxidative Apoptosis in SH -SY5Y cells
- Identification of unlawful components in food using direct-infusion mass spectrometer
- Decursin Qualification of Angelicae Gigantis Radix cultivated by GAP(Good Agriculture Practice )
- A nti-inflammatory Activities of E thanolic Extract and Its Subfractions from Gastrodiaelata
- Increases of Lipoprotein Lipase Activity in the Experimental Autoimmune Encephalomyelitis (EAE )-induced Mice
- Neuroprotective effect of M0126E -K5 in SH-SY5Y cells with oxidative stress and transient global ischemia model in gerbils
- A0103E -K42 Attenuates Sodium Nitroprusside-Induced Neuronal Cell Death in Human N euroblastoma SH -SY5Y Cells and Primary Cortical Culture in Gerbils
- Identification of Cackayne Syndrom e AInteracting Proteins
- The role o f Nrf2 and HO -1 in adaptive response to tetrahydropapaveroline -induced a poptosis in PC12 cells
- Anti-inflammatory action of benzoxathiolone LYR-71 compound in macrophages RAW 264 ,7 by suppression of interferon -gamma-induced JAK-STAT signaling pathway
- HIV integrase inhibitory caffeoy l-carboxylic acid and amide derivative
- Benzimidazole -4 ,7 -diones as Selective Inhibitor of Endothelial Cell Proliferation
- Design, Synthesis and Cytotoxicity Test of Psorospermin /Quinophenoxazine Analogues
- Synthesis and biological evaluation of quinoxaline -5 ,8 -diones that inhibit vascular smooth muscle cell proliferation
- Acyl-CoenzymeA ：cholesterol acyltransferase(ACAT ) inhibitory effect of glabrol isolated from the roots of Glycyrrhizae Radix.
- Preparative Purification of Natural Products using Centrifugal Partition Chromatography
- Purification of tonic substance from silkworm pupa male and mechanism of action
- Subacute Oral Toxicity of natural Phellinus linteus in Sprague -Dawley Rats
- Antioxidant effect of fenilic acid and sesamol on B16F10 murine melanom a cell
- Inhibitory Effect of Inflexinol on Nitric Oxide Production and NF - kB Activation
- The effect of chlorhexidine digluconate on lateral and rotational mobility of phospholipid mixture liposomes.
- Self-Assembled Nanoparticles for Cancer Imaging and Therapy
- CW 2007 from Torilis japonica Blocks hKv l.5 Channel Current
- T he effect of flavonoid fraction extracted from Rhus verniciflua Stokes on sexual behavior in SD male rats
- Inhibition of MHC-restricted antigen presentation pathways in vivo by immunosuppressive calcineurin inhibitors
- Anxiolytic-like Effects f Quercetin Using the Elevated Plus-Mazeand Hole-board Apparatus in Mice.
- An olefin disconnection strategy for the practical synthesis of (+ )-brefeldin A ： cross metathesis and intramolecular Homer-Wardsworth -Emmons olefination
- Screening and Identification of PTPIB Inhibitory Natural Products for the Treatment of Type 2 Diabetes
- Sulforaphane inhibits phorbol ester-induced COX-2 expression in human breast epithelial cells ：IkB kinase p as apotential target
- C y c looxygenase -2 inhibition attenuates lipopolysaccharid e -induceddopaminergic toxicity.
- Effect of Sophorae Radix on anti-40CD and recombinant interleiikin-4- induced cytokine production in murine B-cells
- Quantitative analysis of anthraquinone and stilbene deriva ives in various rhubarbs
- Protective Effect of Tissue Cultured Root of Mountain Panax ginseng C A . Mayer against 2 ,3 ,7 ,8 -tetrachlodibenzo -p -dioxin Induced Toxicity in Rat
- Reduction of oncogene expression in cancer cells using siRNA delivery systems
- Dose Dependency in the Oral Bioavailability of an Organic Cation Model, Tributylmethyl ammonium (TBuMA), in Rats
- Molecular Cloning of the Gene Encoding the Thermostable L-Asparaginase from Streptomyces lincolnensis M -20
- Genexol-PM , a polym eric micellar paclitaxel formulation, suppresses primary tumor growth and lung metastasis in a green fluorescent protein orthotopic model of breast cancer
- Virus Validation for Plasma Derivatives
- Bisphenol A -in duced immunosuppression in 7 -weeks -old offsprings of mice.
- Fatal Poisoning Cases due to Benfuracarb or Furathiocarb Ingestion
- Isoflavonoids Isolated from Pueraria Radix Is Potent Inducer of Heme Oxygenase -1 And Nrf2/ARE Signaling.
- Comparative Evaluation of Scoring Functions for Virtual Screening
- The inhibitory effect of the biologically active components from Oriental medicines on the m icroglial activation
- Hepatic geneex pression profiles study in the mouse liver by acute ethanol exposure induced steatosis
- Effects of Aster spathulifolius extracts (ASE) on fat accumulation, lipid profiles and UCP expression in high fat diet induced obese rats
- Endotoxin Induces Downregulation of TNF -a/iL-10 and Increased P oduction of IL -6 in P ristane-Primed Chronic Inflammation ICR Mice
- Form aldehyde-Induced gene expressio n in Human Trachea Hs 680 Cell Line
- Effects of L-DOPA on dopamine biosynthesis and cytotoxicity in PC12 cells
- Reduction o f mechanical pain by spider toxin
- Potent anti-breast cancer activity of a novel inhibitor of HD AC, IN -2001 in vivo MMTV /c-Neu mice
- Amelioration of age -related inflammation and oxid ative stress by PPARy activator : Suppression of NF -kB by 2,4-thiazolidinedione
- INHIBITION OF ANTTOXIDANTS AND CYP450 INHIBITORS AGAINST AIRBORNE PARTICULTE EXTRACT-INDUCED GENOTOXICITY
- Rho K inase Activation during Acetylcholine-induced Contraction of Cat Esophageal Smooth Muscle
- Comparison o f Sim ultaneous Extraction Methods for Basic Drugs in Biological Specimens
- Berbamine inhibits rat aortic vascular smooth muscle cell proliferation and cell cycle p rogression through inhibition of ERK l/2 activation and Rb protein phosphorylation
- The Effect of DA -8159 , a Novel PDE5 Inhibitor, on Erectile Function in th e Rat model of Hypercholesterolemic Erectile Dysfunction
- A denovirus mediated p53 treatment enhances photodynam ic antitumor response
- Photodynamic effects of Radachlorin on cervical cancer model
- Effect of A 0054E on Quinone Reductase [(NAD(P)H ： quinone oxidoreductase, OR] and on H ydrogen Peroxid e-induced Oxidative DNA Damage
- Protection of EGCG and ginsenoside Rgl against oxidative stress by th emodulation of ceram ide level in LLC-PK l cells
- In Vitro and In Vivo Antifungal Activities of Itraconazole-PM , a Polymeric Micellar Formulation of Itraconazole
- AMPK -mediated Cell Death by Metformin under the Condition of Oxidative Stress：Inhibitory Role of AMPK in Phase II Antioxidant Enzyme Induction
- Contents of Heavy Metals in Commercial Herbal Medicines in Seoul
- Determination of AUantoin in Dioscoreae Rhizoma by HPLC
- Monitoring(n) of Pesticid e Residues in Commercial Herbal Medicines
- The effect of shampooing on concentrations o f Methamphetamine and MDMA in human hair
- Role of de novo ceram ide synthesis in SK-1-induced apoptosis
- Estrogenic Effects of Marijuana Smoke Condensate (MSC) and Cannabinoid Compounds
- Role of Oxidative Stress in Peritoneal D ialysis Solu tion -induced Peritoenal Alteration
- Integration system for ageing research based on distance einalysis between factors
- A Short and Efficient Synthesis of L-Carbohydrates
- Dependence, neurotoxicity and memory impairment induced by dextromethorphan.
- Effect of extract from Punica granatum and some herbal extracts mixture on general postm enopausal symptom in vitro.
- Development of Controlled-Release Pellets with Sodium Alginate and Surelease？？ using Extrusion/Spheronizatdon
- Expression Profiling of Cellular Process in Squamous Cervical Cancer Omic Approaches and Its Correlation with Array-CGH
- Quantitative Determination and Structural Identification of Ten Major Saponins in Platycodi Radix by HPLC with ELSD and LC-ESI tandem MS
- Novel Anti-Depressant Effects of Nelumbinis Semen
- Determination of famotidine in human plasma by high-performance liquid chromatography.
- T e Role of Phospholipase A2 and Its Metabolite in Histam ine Release in RBL 2H 3 Cells
- 3D-QSAR study of 2- Phenyl- 1,8 -naphthylridin-4 -one with anticancer activity
- Transcriptional configuration o f m ou se cerebral cortex by long -termex posure to 3, 4 -m ethylenedioxym etham phetainine (MDMA) through gene expression profiling
- Risk Assessment of Heavy metals in PM 2.5 and PMIO
- Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice
- Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1 -expressing glioblastoma cells
- Screening of pharmaceutical excipients on hepatic metabolism of olanzapine, in vitro
- Cryptotanshinone, One of the Major Ingredients of Salviae Miltiorrhiza Bunge(Dansham),Inhibits Rabbit Platelet Aggregation by Reducing Intracellua Ca Mobilization and Arachidonic Acid Liberation
- Anti-wrinkle E ffect of Acanthopanax extracts in Human Dermal Fibroblast,
- Determination of eperisone in human plasma by liquid chromatography-tandem mass spectrometry
- Drug Discovery at the Interface between T\imor Immunity and Autoimmunity
- Panax ginseng increases hypoxia-induced dow nregulated cellular response related genes in human neuroblastom a cells
- Rapid Screening of blood-brain barrier penetration of drugs using the immobilized artificial membrane phosphatidylcholine column chromatography
- Effect of morin on the paclitaxel bioavailability after oral and intravenous administration of Paclitaxel in rats
- Anti-diabetic Effect and Mechanisms of KHP-03
- Inhibition of tyrosin ase activity by N ,N -iansubstituted selenouread erivatives
- A ntitum r Constituents from the Bark of Tilia amirensis
- Single Nucleotide Polymorphism (SNP) Detection In Microfluidic Device Using Poly(NIsopropyDAcrylamide As Pseudostationary Phase
- Evaluation of cholesterol in hair of patients with hyi>ercholesterinemia
- Crystal Structure of Prophenoloxidase Activating Factor-II, a Clip Domain Family of Serine Protease
- Rapid determination and validation of losartan in human plasma by liquid chromatographytandem mass spectrometry and its application to a bioequivalence study
- Heme Oxygenase-1 Induction by YS 51, An Analogue of Higenamine, Inhibits Nitric Oxide-Induced Apoptosis of ROS 17/2.8 cells
- Changes of Gene Expression Related to Cisplatin Resistance in Gastric Cancer Cell
- Synthesis and screening of cyclooxygenase activity of 9-amino-l,2 ,3 ,4- tetrahydroacridine derivatives.
- Immuno-modulating effect of Mountain cultiired ginseng
- Nrf2 Protects against Oxidative and Nitrosative PC12 Cell Death through Up-regulation of -Glutamylcysteine Ligase and Heme Oxygenase-1
- Pharmacokinetics of gabapentin in Rat with Acute Renal Failure Induced by Uranyl Nitrate
- Enhanced anticancer efficacy of a-tocopheryl succinate by polyethylene glycol conjugation
- Nicotine attenuates kainate-induced neu rotoxicity via activation of a7 nAChR in the rat.
- Characterization of Immune Responses Induced by Intramuscular Vaccination with DNA Vaccines Encoding Measles Virus Hemagglutinin and/or Fusion Proteins
- Synthesis, Structure-Activity Relationships, and Mechanism of Action of Novel Indirubin Derivatives as Potent Anti-proliferative Agents with CDK2 Inhibitory Activities
- Small-Molecule Inhibition of Siderophore Biosynthesis in Mycobacterium tuberculosis and Yersinia pestis
- Synthesis and Cytotoxicity Test of Xanthone Derivatives as Anticancer Agents.
- Activities of the Novel Oxazolidinone Analogues Against Staphylococcus aureus in Murine S ystemic Infection Model
- Effect of L-Carnitine Supplementation on Cardiac Carnitine Palm itoyltransferase Activities and Plasma Carnitine Concentrations in Adriamycin Treated Rats
- Quantitative analysis of oxidation dye components in hair dyes
- Relatively high amount of IL-3 2 q isoform is constitutively produced in human T cell leukemia cell line Jurkat compared with other human cell lines.
- Pulmonary delivery of Lys^-mono-PEGylated glucagon-like peptide-1 (7-36)： Hypoglycemic effect and pharmacokinetics
- Phenolic Constituents from Tetragonia tetragonoides
- Red wine polyphenolic compounds strongly inhibit pro-MMP -2 activation in response to throm bin via direct inhibition of MTl-MMP in vascular smooth muscle sells
- Acteoside of Callicarpa dichotoma attenuates scopolamine -induced memory impairments
- Comparison o f M oxifloxacin Monotherapy versus Cephalosporin - A zithrom ycin Combination Therapies for Community Acquired Pneumonia
- In hibitory Effects of Paeonol on Morphine-Induced Reverse Tolerance and Conditioned Place Preference in Mice
- A study on evaluating quality of service in pharm acy using SERVQUAL
- Consideration of Physical and Biological Factors for Oral Drug Bioavailability
- Pharmacokinetic and PK/PD modeling of dihydropyridine calcium channel blocking agents in cardiovascular effect.
- Treatment with FermentaGinseng Decreases Colonic Inflammation in the Murine Model of Ulcerative Colitis
- Enhanced Cellular Uptake of Cytarabine via a Petidyl Prodrug, L-Valyl-Cytarabine in Caco-2 Cells
- Inhibition of Diacylglycerol Acyltransferase by lupane type triterpenoids from the bark of Betula platyphylla var. japonica
- A Molecular Mechanism for Hair Growth Effect of Minoxidil
- The Stability of cefditoren pivoxil in Tylenol？？ and Febron？？ oral liquid syrups
- Role of Cadherins in Bone Biology
- Deterzniiiation of sildenafil, tadalafil, vardenafil and their analogues in food marketed for penile erectile dysfunction by HPLC-UV
- Cytoprotection against oxidative damage by Nrf2 - regulated genes: Induction of the 26S proteasome
- The Cytotoxic Saponin from Heat-Processed Achyranthes faurici Roots
- Studies on Target Microbial Contamination of Herb Medicines
- Hepatoprotective Effects of Chrysanthemum indicmn Liime Extract in Rats treated with CC14
- The Effect of Taurine Chloramine on PMA -elicited Superoxide Anion Production： T au-C l Modulates NADPH Oxidase A ssembly
- Monoclonal Antibody and Its Therapeutic Approach
- Enantioseparation of Urinary Naproxen and 6-0-Desmethylnaproxen as Diastereomeric (R)-(+ )-1 -Phenylethylamides after Oral Administration of (S)-Naproxen by Achiral Gas Chromatography
- Analysis of depiorination of guanine-b ased nucleosides with 2-bromopropane and other structurally similar halogenated alkanes at the physiological condition by using HPLC and LC/MS/MS.
- Synthesis and In Vivo Evaluation of Selenoflavanone
- Developement of Metalloproteinase Inhibitors from a Fungal Metabolite, Gelastatin
- Chemistry of Plant Polyphenols in Foods and its Contribution to Human Health
- Construction of Thesaurus for Human Gene and Protein Nomenclatures
- Regulation of Transduction Efficiency by Pegylation of Baculovirus Vector in vitro and in vivo
- AKAP12 down -regulates the H IF -la stability
- Anti-hepatofibrotic effect of Rhus vemiciflua Stokes flavonoid extract in human hepatic stellate c e ll line, LI90 and hepatom a cell line, HepG2 cells
- Involvem ent of K ,Cr-Cotransport-Mediated Generation of Reactive Oxygen Species in M elan ogen esis Induced by A pigenin in B16 Melanoma Cells
- Neuroprotection of ginsenoside Rg3 and signal evidences in neuroblastom a cell line (SK-N -MC )
- A Pharmacokinetic Study to Compare the Absorption Characteristics of Single-, Multi-dose of Transdermal Nicotine Patches
- The protective effect of QGC on gastritis in rats.
- Identification of Taxol-Resistant Genes in Mouse Fibroblasts Transfected with a cDNALibrary from Breast Cancer C ells
- Anti-inflammatory Activity of Punica granatum Extracts ( I )
- Effects of Dicyclomine on Methamphtamine-lnduced Behavioral Sensitization and Dopamine Release as Measured by in vivo M icrodialysis in Mice.
- Synthesis and Cytotoxicity of Novel Cyclic Ceramide Analogues
- Application of a Sample Pooling Method for the Accelerated Assessment of the Rate of Uptake of Drugs by the Brain in Rats
- Structural, biological, and glucodynamic properties of [N-bile acid Lys] human insulin analogues
- Structure-Activity Relationships of 4 '-Thionucleosides As Potent and Selective Human A3 Adenosine Receptor Agonists
- Mechanism of prolonged gene expression by Epstein -Barr v irus-based plasm id in porcine cells
- DNA Gyrase and Topoisomerase IV Are Dual Targets of DW -224a in Streptococcus pneumoniae
- Tota l Synthesis of PM -94128
- Subacute Im munotoxicity of a Synthetic Propenone Compound, -Furan-2-yI-3-Pyridin-2-yl-Propenone in Mice
- The Effects of Carbapenems on the Pharm acokinetics of Valproic Acid
- Synthesis, Pharmacology and Molecular Modeling of New Piperidine derivatives for A lzheimer's disease the rapeutics
- Feasibility Studies for Buccal Transport of Paclitaxel： Influence of Vehicles and Permeation Enhancers
- Involvement of h istaminergic nervous system in the anxiolytic- like activities of Morus alba L. leaves in mice
- Comparative Studies of Intracellular Trafficking Pathways of Dopamine D2 and D3 receptors
- Development and Validation of a Bioanalytical LC-MS/MS Method for the Quantitative Determination of Amisulpride in Human Plasma
- Effects of 2, 4 -D and DCP on the DHT -induced androgenic action
- CCR5 -mediated promotion of neurogenesis of neuronal stem cells by cytokines and chemokines released from astrocytes
- Geranti Bio -Ge Y east, Dried yeast containing Biogennaniiun. enhances the production of Antibody via more B cell proliferation
- Kainate-induced hippocampal mitochondrial degeneration is more susceptible to senile-prone (P8) strain than senile -resistant (Rl) strain of senescence-accelerated mice.
- A new paradigm of Biphenyl Dimethyl Dicarbohydrate as an antiviral agent
- Chemical and Physiological Synthesis of N 3-Adenine Adducts by 1- and 2-Bromopropane, and A nalysis of their Adenine Adducts by HPLC and LC/MS/MS
- Topical delivery of IL-13 AS-ODN with cationic elastic liposome for the treatment of atopic dermatitis
- Pandemic Preparedness: Immune Responses of Live Influenza Vaccine
- 2"-Hydroxycinnam aldehyde inhibits SW620 colon cancer cell growth through prevention of AP -1
- DNA-Based Immunotherapy for Chronic Disease Such as T\iberculosis
- Revised Provision for SpeciHcations and Test Procedures of Drugs
- Correlation of Serum Thyroglobulin before the 1st 1-131 Remnant Ablation and Change of Thyroglobulin and C ervical 1-131 U ptake after Abladon
- Activation of NF -kB by HDAC inhibitor apicidin through Sp1 - dependent d e novo protein synthesis: its im plication for resistance to apoptosis
- PTPIB inhibitory effect of lignans isolated from Myristica fragrans
- Formulation and Evaluation of solution Preparation containing Ivermectin
- Rapid, simple and highly sensitive LC-ESI/MS/MS method for the quantitation of buspirone in human plasma： application to a pharmacokinetic study
- A Role for "Local" Protein Synthesis in Synaptic Plasticity, Learning & Memory
- Rubiae Radix Suppresses the Activation of Mast Cells through the Inhibition of Syk Kinase for A nti-allergic Activity
- Inhibitory effects of the stembark extract of grapevine on the proliferation of human tumor cell lines
- Epothilone B and D arrest cell growth via inhibition of N F -kB signaling pathway in SW 620 cells
- In hibitory effect of CBPharm -001 on lipopolysaccharide -induced cognitive dysfunction and its action mechanism
- Synthesis of Vermiculine and It"s Derivertives via Making Macrodiolide Conformation with selenol ester
- Docking of a series of norindenoisoquinoline topoisomerase 1 poisons into human topoisomerase I with FlexiDock
- The Formononetin Content Comparison of Astragali Radix with different cultivated regions by cultivated GAP(Good Agriculture Practice )
- Sialoglycoprotein-binding protein from the edible mushroom Cordyceps militaris
- Separation of N-FMOC a-amino-acids enantiomers by Liquid Chromatography and Capillary Elelectrochromatography
- Analysis of losartan in human plasma using high-performance liquid chromatography with fluorescence detection
- Inhibition of COX -2 Down-regulates cAM P-induced TRANCE Expression in Osteoblasts
- Anti-proliferative effects of the lignan components from Myristicae Semen on cultured human tumor cell lines
- Influence of Nelumbo nucifera GAERTN on the Response of Stressful Stimuli.
- Total synthesis of (+ )-macrospheldie A and B
- Studies on Immuno-Modulatoryand Antitumor Effects of Salicomia herbacea Extract
- Binding affinity test of aminoglycoside antibiotics to the HIV-1 Rev Responsive Element
- Enantioseparation and evaluation of naproxen by HPLC
- Sensitive column-switching high-performance liquid chromatography method for determination of propiverine in human plasma
- Development and Validation of HPLC-UV method for the Determination of Tranilast in Pharmaceutical Preparations
- Design, Synthesis and Biological Study of Novel Psorospermin/Quinobenzoxazine Hybrid Compounds
- Phytochemical Constituents of Prunus padus
- Reactive oxygen species mediate ET-1- induced activation of ERK l/2 and SAPK /JNKs signaling in cultured felinee sophageal smooth muscle cells.
- Immune-Enhance Effect and Its Mechanism of Scrophularia Buergeriana .
- Modulatory Effect of Coffee Diterpene Kahweol on A cute Inflammation in The Rat Air Pouch Model
- Triphlorethol-A Activates Heme Oxygenase-1 in Lung Fibroblast Cells via Up-Regulation of NF-E2 Related Factor 2
- Biotechnological Product Assistance Project- from Bench to Brand
- Structures of Enzymes and Drug Discovery
- Single pathogenic bacteria detection using a compact CMOS biochip system
- Eupatilin,a pharmacologically active flavone derived from Artemisia plants , protects cultured felin e ileal smooth muscle cells from indomethacin.
- A New Drug for Luminal Amoeb asis ： Synthesis and Properties of Dextran-Metronidazole Succinate as a Colon -Specific Prodrug of Metronidazole
- Pharmacokinetic Modeling of Testosterone Metabolism using Primary Cultures and Cryopreserved Hepatocytes
- Identification of a novel form of 30 kDa membrane-associated and neutral sphingomyelinase and its role inexocytosis mechanism of neurotransmitter
- All-trans Retinoic Acid Overcomes a Doxorubicin -Resistant Phenotype via Induction of Fas /Fas L igand System in Acute Myelocytic Leuke ia Cells
- Prenylflavone Derivatives from Psoralea Corylifolia Inhibit Nitric Oxide Synthase Expression through the Inhibition of IKB Degradation in Activated Microglial Cells
- Enhanced solubility of paclitaxel in the liposomes： effect of the composition
- Cytotoxic Phenylpropanoids from the Rhizomes of Alpinia galanga
- Potent Inhibitory E ffects of N -A ryl S-A lkylthiocarbamate Derivatives on Melanin Production
- Possible role of ceramide in lung injury induced by diesel exhaust particles
- The Pharmaceutical Effects of Antimicrobial Molecules from Arthropoda
- Modulation of P-glycoprotein Activity by Kaempferol Derivatives
- Effect of Piogiitazone on Cerebrovascular Blood Flowin Type 2 Diabetic Patients
- Glycosylation pattern of recom binant CTLA4Ig from transgenic rice cells
- Role of Monocarboxylic Acid Transporters in the Intestinal Absorption of Carboxylic Acid Drugs
- The Validation of Anti-Cancer Targets by Clinicopathological study: TGF-P Signaling in Gastric Carcinoma
- Isolation of Butein from R hus vemiciflua and Synthesis of Its Derivatives w ith Anti-inflammatory activities by inhibiting production of Nitric Oxide
- B ifim ctional e ffect of resveratrol on theexpression of ErbB 2 in human breast cancer cell
- IdentiHcation of Novel Targets for Cancer Therapeutics through Genome Expression Profiling
- A new norditerpenoid alkaloid from Aconitum sp. cultivated in Korea
- A nticolitic effect of Ginseng
- Effects of D i(n-butyl)phthalate on Gene Expression of the Male and Female Reproductive Organs
- N -Glycosylation Analysis of Recombinant Human Tissue Plasminogen Activator Produced in Urea Cycle Enzymes Expressing CHO Cell Line
- The study of metabolite-to -parent drug ratios of Methamphetamine and Methylenedioxym etham phetam ine in hai
- The Smoking-Related Factors and Smoking Cessation in Korea
- Critical Domains in the Heterotrimeric G protein Subunit for Interaction with Receptors and Effectors
- Revised Provision of Stability Test
- Diememorfan, a dextromethorphan analog, attenuates methamphetamine-induced dependence and dopaminergic toxicity via the inhibition of cannabinoid CB 1 receptor
- Alkamides, ACAT inhibitors from the fruits of Piper nigrum
- Effect of a natural extract on symptoms of the alcohol hangover
- Molecular Mechanism of Na,K-ATPase Inhibition by Ouabain：Ouabain Dephosphorylates Cofilin through the Ras/MEK/ERK Pathway
- Inhibition of human secretory non-pancreatic phospholipases A2(PLA 2) Involved in inflammation
- Kidney Medulla-Specific Reduction in the Distribution of TEA in rats with Uranyl nitrateinduced Acute Renal Failure.
- Synthesis of New 3 -Alky amino -6 -allylthiopyridazine Derivatives
- Inhibitory effects of madecassic acid on the productions of NO, PGE2, TNF -a and IL-lp via the suppression of NF -kB pathway in LPS-induced macrophages
- Studies on Comparative Analytical Methods for Minerals in Multi-Vitamins with Minerals Pharmaceuticals
- p38 MAPK Mediates Ceramide-induced Apoptosis through the Phosphoinositide 3 -k inase-Akt Pathway
- Discovery of a Novel PPARy Agonist, KR62980 with New Indication of Osteoporosis Treatment
- Effect of Traditional Herbal Medicine on the Formation of Advanced Glycation Endproducts (AGEs) in Vitro
- Asymmetric synthesis of 1,2 -diol and its app ication to the synthesis of (+ )-clemastine
- The T\imor Suppressor, p l6 Prevents Cell Transformation Through Inhibition of c-Jun Phosphorylation and AP-1 Activity
- Preparation and evaluation of clavulanic acid-loaded Eudragit^ microspheres for sustained release and enhanced stability
- Stealth Cell Delivery for Self-Regulating Glucose Level
- Induction o f G lutathione S - Transferase in IGF type I receptor overexpressed hepatoma cells
- A 24-nor-Triterpenoid from the Steins of Rumex japonicus with Advanced Glycation End -products (AGEs) Inhibitory Activity
- Hepatoprotective Effects of Viticis Fructus Extractin Rats treated with CC14
- In Silico Screening of Angiogenesis-related Genes in Hepatocellular Carcinoma using Protein Interaction and Expression Data Base
- Immunosuppressive effect of poly(RGD) sequence on allogenic CTL induction in mice
- Development of Anti-arthritic Therapeutics from Saponins
- TGF -p Modulates Expression of MMP-2 and MMP-9 through p38 Signaling in Breast Epithelial Cells
- Chemical modification of santonin confers the ability to in duce the differentiation of human promyelocytic leukemia cells： Involvement of N F -k B, PKC, ERK an d PI3 -K
- LY2821 Inhibits Rat Aortic Vascular Smooth Muscle Cell Proliferation by Upregulation of p27
- Regulatory Effects of K Jl on Macrophage-mediated Immune Responses
- Mechanism of Functional Impairment of the Rat Taurine Transporter by Nitrogen Oxide: Evidence for the Activation of Nitrogen Oxide by Superoxide
- Toxicogenomics Concepts and Applications to Develop New Pharmaceuticals
- The Effect of Taurine Chloramine on LPS-Induced NO Production： Tau -C l Regulates Ras-ERK-NFkB Signaling Pathway
- Antioxidant Properties of Ttingtungmadic Acid Isolated from Salicomia Herbacea
- Prevalence and Determ inants o f Influenza Vaccination in Koreans
- Development of Anti-Bacterial Agents by Using Structural Information
- Implementation strategy for the regulations on the package unit for the medicine
- In vitro and in vivo anti-inflam m atory activity of Q -linolenic acid isola ted from Actinidia polygam a fruits
- Evidence that Protease-activated Receptor -2 M ediates Trypsin -induced Reversal of Stellation in Cultured Rat A strocytes
- ERK-m ediated production of neurotrophic factors by astrocytes promotes neuronal stem cell differentiation by ery thropoiein
- Physicochemical characteristics of solid lipid nanoparticles loaded with isotretinoin for topical delivery
- Synthesis of Arginine-grafted Dendritic Block Copolymer for Gene Delivery and Its Cellular Uptake Mechanism Leading to Effective Transfection.
- Synthesis of N -Phenylsuccinimide Derivatives as Novel T- type Ca Channel Blockers Based on SBDD
- Revision of the Korean Pharmaceutical Codex, The third Edition
- Quantitative Analysis of Polygonati Rhizoma
- Functional role of a novel form of 60 kDa Mg-dependent neutral sphingom yelinase
- In Rabbit M icrofracture Model Controlled Dehydroepiandrosterone-sulfate Release from PLGA Rod -type Implant Enhanced Cartilage Regeneration
- Identification of the Insulin Signaling Cascade in the Regulation of A lpha -Class Glutathione STransferase Expression in Primary Cultured Rat Hepatocytes
- Effect of gamma irradiated phyticacid on the function of immune cells
- Discriminating the Molecular Basis of Hepatotoxicants through Expression Profiling Analysis
- Protection and therapeutic effects of the herbal preparations containing bacalein and 6 -gingerol in the treatment for dermatits
- Metabolism of Tryptanthrin a Cyclooxygenase -2 Inhibitor in Rats in Vitro
- In-line Monitoring the Mixins Ratio of UFT Granules in Final Product Packages by NIR Spectroscopy
- Akt-G SK 3p pathway underlies the cardioprotective effect of KR -32568 , a novel sodium/hydrogen exchange r-1 inhibitor, in an isolated rat heart m odel of ischem iaand reperfusion heartinjury
- Post-marketing Surveillance Study of the Safety and Efficacy of Mesoglycan Prescribed in Primary and Secondary Care of Patients with Vascular Disease.
- Growth hormone releaser attenuates memory impairments via phosphorylation of A KT/G SK3b and activation of muscarinic Ml receptorin the genetic model of aging gene K lotho mice.
- Enhanced oral bioavailability of poorly water-soluble piroxicain by sodium hyaluronate- based solid microsphere using spray-drying method
- Prescription Order for Splitting Use of Tablets and Capsules in Korea
- Antioxidant activity of myricetin p resence of taurine
- PK/PD modeling for antiplatelet and cardiovascular effect of triflusal in human
- Characteristics of Pharmacogenomic and pharmacogenedc of 5 -FU in Koreans
- Conception and Synthesis of Aromatase Inhbitor
- Antiinflammatory effect of rotenoids from fruits of Amorpha fruticosa
- Cholinesterase inhibitory activity of oligostilbens from Vitis amurensis
- Effect of CYP2C9 polymorphism on the pharm acokinetics of lomoxicam in healthy Korean subjects
- Improved detection of microbial growth using automated culture system BacT/ALERT 3D.
- Anti-complement Activ ty of Constituents from the Leaf and Twig of Acer okamotoanum
- The reactivity of chalcone on the oxidative cyclization.
- A Study on Establishment of Assay method by HPLC of Herbal Medicinal Preparations containing Comus Fructiis.
- Inhibitory Effect of Euscaphic Acid and Tormentic acid from the Roots of Rosa nigosa on H igh Fat Die t-Induced Obesity in the Rat
- Total synthesis of Costunolide
- Synthesis of the carbocyclic phosphoramidite derivative of 2 '-deoxy- 2 '-C-p-methylcytidine
- Hepatoprotective Effects of Brassica campestris L. var. rapifera
- Inhibitory Effects of Phenolic compounds from Lysimachia clethroides DUBY on the Melanin Biosynthesis
- Determination of cytochrome P450 enzymes involved in the metabolism of rutaecarpine in human liver microsomes
- Identification of Hoelen Species in the Herbal Medicinal Products Using Molecular biological analysis Method
- Saturable Distribution of Tacrine into the Striatal Extracellular Fluid of the Rat： Evidence of Involvement of Multiple Organic Cation Transporters in the Transport
- Sesquiterpenes from Saussurea macrolepsis
- Clinical significance of CD99 downregulation and its mechanism in gastric adenocarcinoma
- Role of Translationally Controlled T\imor Protein in the Pathogenesis of Hypertension
- Point to Consider in Recombinant Products Evaluation
- Immunosuppressive Effects of Carbon Monoxide, a Gaseous Product of Heme Oxygenase-1
- Thermostability, Substrate Specificity and Transphosphatidylation of Phospholipase D from Streptomyces sp.
- Saponins Derived From Roots of Platycodon Grandiflorum Reduce Endothelial Adhesion Molecules ICAM-1 And VCAM -1
- Oral delivery of pooly water-soluble genistein incorporated in solid lipid micro/nano-spheres
- Inhibitory action of alpha-viniferin from Carex humilis on interferon-gamma-induced nitric oxide production
- Improvement of bioavailability and photostability of amlodipine using redispersible dry emulsion
- Study on the hydrolysis mechanism of PDE4D
- Determination of P lasma Tulobuterol Concentration by Gas Chromatography
- Preparative Resolution of the bevantolol Enantiomers
- Inhibitory effe t of irradiated LPS on L PS-induced endotoxemia
- Glucosylated Polypropyleneimine Dendrimer as a Novel Gene Carrier
- Prediction of Human Intestinal Permeability of Drugs from in-vitro Experiments
- Heparin, Low Molecular Weight Heparins and Analogs as Pharmaceutical Agents
- The Anti-inflammatory and Anti- nociceptive Effects of Ethyl Acetate Fraction of Cynanchi Paniculati Radix.
- Synergistic Induction of Growth Inhibition and Apoptosis in Cancer Cells by ID-6105 and Doxorubicin, Alone and in Combination with Tissue Cultured Mountain Ginseng Extract.
- Simultaneous Determination Of 16 Antiretroviral Drugs In Human Plasma For Quantitative Analysis With Liquid Chromatography-Tandem Mass Spectrometry
- Analysis of Prescribing Pattern with the Negative List Formulary System in Korea
- Efects of Six Polycyclic Aromatic Hydrocarbons on Liver and Lung Microsomal Cytochrome P450s in Rats
- Role of Early Growth Response Factor-1 and Hepatocellular Hypoxia in the Development of Chronic Liver Disease
- Inhibitory Effect of Ficus carica on the Lipid Production in Human Sebocyte Cell Line
- Identification of three plant extracts competitively inhibiting a 60 kDa membrane-associated ,Mg-dependent and neutral sphingomyelinase activity from Korea domestic natural plants
- Regulation of Tissue-Specific Gene Expression by Coordinated Changes in DNA Methylation and Histone Modifications in the Coding Region
- Qualitative Analysis o f Amitriptyline , Imipramine and their Metabolites in Blood by GC-MS
- DNA Topoisomerase II Inhibitory Activity of Procyanidin B4 from Mucuna birdwoodiana
- Antioxidant compounds from Aerial Parts of Atractylodes macrocephala .
- Preparation and Characterization of PLGA N anoparticles for Sustained Drug Delivery
- Capsaicin enhances the anticancer effect of 5-fluorouracil through peroxisome proliferatoractivated receptorg pathway in HT-29 human colon cancer cells
- Potent inhibition of human cytochrome P450 IBl by 2,2" ,4,6" -tetramethoxystilbene.
- Structure - activity Relationship of Multihydroxyursane-type Triterpenoids on the Inhibitory Effect of TPA -induced Ear Edema
- D ifferent Expressions of Platelet Glycoproteins between Catecholamine Responders and Nonresponders
- N-methyl-N-propyny l-2 -phenylethylamine, a selegiline analog attenuates MPTP-induced dopam inergic toxicity：com parison with the effects of selegiline.
- Inhibitory effects of Artemisia princeps on passive cutaneous anaphylaxis reaction
- Current development and Evaluation of Vaccine & Safety & Efficacy Evaluation of Vaccines
- Development of Vaccines to Emerging / Reemerging Virus: SARS - A Case Study
- Petrotetrayndiol A from Sponge Petrosia sp., Induces A poptosis in Human Skin Cancer Cells
- INHIBITORY ACTION OF qj-CONOTOXIN GVIA AND CELNIDIPINE ON CATECHOLAMINE SECRETION
- A linker Molecule for Regulating Inflammation and Angiogenesis
- Synthesis of New 3 -A Uylthio -6 -aminopyridazine Derivatives and Their Antihepatocarcinoma Activity
- Correlation between antioxidative and antinephrotoxic activity of (+ )-catechin-7 -0 -p -xylopyranoside under renal injury
- Formulation of Transdermal Drug Delivery Systems Containing Fentanyl
- Protein tyrosine phosphatase IB inhibitory activity of triterpenes isolated from Astilbe koreana
- Thioredoxin/TRX-Dependent Redox Regulation of Inflamamatory Process
- Anti-inflammatory Effects of Apigenin on Lipopolysaccharide-induced Activation of Microglia is M ediated by Inhibition of the NF -kB Pathway in BV -2 Cells
- Pharm acokinetics of aceclofenac and its metabolites in human
- Induction of cell cycle arrest and apoptosis mediated by xanthorrhizol in human colon cancer cells
- Development of New Histone Deacetylase Inhibitors using Chemical Genomics
- Design and Synthesis of N-Aryl-6-hydroxy-7-methoxy- 2 -chromancarboxamide Derivatives
- Molecuiar Mechanism s of Inhibitory Effects of PLG. an alkaloid from Piper longum L., on Throm bosis and Atherosclerosis D evelopment
- The Role of Epidermal Growth Factor in Enhancing Dermal Matrix Regeneration and Its Implication in Wound Contraction and Scar Formation
- Development of a Rapid HPLC Method for the Analysis of Anti-impotence Drug Analogues in Foods using a Monolithic Column
- Inhibition of Chronic Skin Inflammation by Topical Anti-inflammatory Flavonoid Preparation,Ato Formula
- Process Analytical Technology (PAT); What is PAT
- Design and Synthesis of F luorocyclopentenyl-pyrimidines as Potent Anticancer Agents
- Clotrimazole cause G1 cell cycle arrest in HT -29 human colorecta l cancer cells
- Chromatographic enantiomer separation of N-benzyloxycarbonyl amino acids and their esters on polysaccharide derived chiral stationary phases
- Honokiol protects rat hepatocytes from bile acid-induced apoptosis
- New Approach to Chiral Oxazolidin-2-one from Oxirane with Use of Chlorosulfonyl Isocyanate
- Effect of Novel Antihypertensive Drug, Fimasartan in Variety of Experimental Hypertension Model
- Analytical Method Validation and Bioavailability Study of Sodium Alendronate in Human Urine
- Strain Improvement of Streptomyces laidlogenes by Antibiotic-Biosynthesis Regulation Genes
- Suppression of Inducible Nitric Oxide Synthase Expression by L ignans from Flos Magnoliae
- Screening of pharmaceutical excipients on solubility, chemical stability and hepatic metabolism of simvastatin
- Effects of Tetrahydropapaverolin e on Dopamine Content and L-DOPA -Induced Cytotoxicity in Differentiated PC12 Cells
- Inhibitory Effects of Moraceae Extracts on Melanin Biosynthesis
- Epigenetic Modification of MGMT in Colon Cancer T issues
- Neuroprotective effect of FuUerene
- The combination of oligodeoxynucleotide and therapeutic vaccines induced by photodynamic therapy enhances antitumor immune response
- In-vitro activities of essential oils from Cnidium officinale against antibiotic-resistant bacteria
- Design, Synthesis and Cytotoxicity on the Benzonaphthofurandione and Benzofuranoquinolinedione Derivatives
- Molecular aspects of human monocytic (U 937) cells during CD29 (b l integrins) activation
- Protective roles of interleukin 6 gene in the trimethyltin-induced neurotoxicity and memory impairment.
- Chem osensitization of Human Ovarian Cancer C ells by a Recombinant Adenoviral Vecotr. AdLPCD, together with 5FC
- Efficacy and Safety Evaluation on Incrementally Modified Drug
- Anti-diabetic Effect and Mechanism s of KHP -01
- LC determination of carbamazepine in human plasma.
- Chemical and Pharmacological Profiling of Natural Products Leads and Herbal Medicines
- DNA Methyltransferase Inhibitor, 5-A zacytidine, Induced Cell Cycle A rrest and A poptosis in Human Prostate Cancer Cell lines.
- Synthesis of l-a llylthio -4 -alkylthio- 5 ,6 ,7 ,8 -tetrahydrophthalazine derivatives for hepatocarcinoma and hepatiszn
- Anti-inflammatory Activity of Trifolirhizin isolated from Methanol Extractof Sophora Flavescens Ait (the Sophorae Radix) in Experimental Animals
- Isolation of Butein from Rhus verniciflua and Synthesis of Its Derivatives with Hepatoprotective and Antioxidative Activities
- Dual Effects of Aspirin on Platelets Aggregation
- E ffect of sea cucum ber Stichopus japonicus on lipid peroxidation and antioxidant enzymes in ovariectomy
- Xanthones, Flavonoids and Secoiridoids from Halenia comiculata
- Highly Enantioselectiv e Epoxidation of 2 ,4 -Diarylenones by Using Dimeric Cinchona Phase -Transfer Catalysts: Enhancement of E nantioselectivity by Surfactants
- Effects of Candesartan on Insulin Resistance and Serum Concentration of MMP-2, MMP-9,TIMP -1, and TIMP -2 in Type - 2 Diabetic Patients with Hypertension
- TNF-a induces invasion by stimulating urokinase-type plasminogen activator and b-catenin signaling in human breast epithelial (M CF-lO A) cells through generation of reactive oxygen species
- Total Synthesis of Manzacidin B
- Hepatoprotective activity of LAB(lactobacillus acidophilus. Bifidobacterium bifidum and Streptococcus thermophilus) in Rat treated with Carbon tetrachloride and Ethanol.
- Inhibition of Lipopolysaccharide -Induced Expression of Inducible Nitric Oxide Synthase by Ethyl Acetate Fraction of Angelica Dahurica in Mouse Macrophage Cells.
- Hypoxia-Stimulated Transcriptional Activation of the eNOS Gene Is Mediated Through the Tax -Responsive E lement (TRE) in Endothelial Cells
- Microarray analyses of gene expression changes by paeoniflorin, paeonol, and albiflorin from Paeoniae Radix
- Anti-Osteoclast Therapy in Bone Disease
- The Korean Red Ginseng Extract Rescues PC12 Cells from PCB -induced Oxidative Cell Death by Activating Nrf2 and Upregulation of Heme Oxygenase-1 and y -Glutamate-Cysteine Ligase
- Determination of Zolpidem Tartrate in human plasma by HPLC with Fluorescence Detection and its application to a bioequivalence study
- A New HPLC Method to Determine Mequitazine in Pharmaceutical Preparations
- DRE-CALUX bioassay for the dioxin level inenvironm ental matrices and human blood
- Implications of Inflammatory and Oxidative Tissue Damage in Gastrointestinal Carcinogenesis
- Application of PAT in Pfizer Global Manufacturing
- Use of Single Nucleotide Polymorphism (SNP) in Toxicogenomic Research
- Patent Map of the Bioavailability Related Pharmaceutical Compositions
- In hibitory effect of alantolactone . a naturally occurring sesquitepenoid , on the growth o f human colon cancer cells
- The Effects of Aquas Extract of M.diantheraCAEMD) on Mast Cell Mediated Immediate-type Hypersensitivity.
- Inhibition of inducible nitric oxide synthase by sumaflavone isolated from Selaginella Tamariscina
- The Chracteristics of Illegal Oral Therapies for Erectile Dysfuntion in Korea.
- Case Report of Aspirin Intoxication
- Chronic toxicity of ch lorostyren es in the nematode Caenorhabditis elegans
- Protective Effect of Gisenosides for Neurotoxicity in Human Neuroblastom a SH -SY5Y Cells.
- Antimelanogenesis effect of phenolic compounds.
- Ulva lactuca Fucoidan and roles of Anti-oxidative emzyme in Ovariectom ized Rat.
- Effect of short-term , low dose aspirin supplementation on the activation of pro-inflammatory NF -kB in aged rats
- Synthesis and antifungal activity of 6-hydroxyciimolines
- Antihistamine Activities of Bradykinin Antagonists on Guinea -pig Ileum smooth muscle contraction
- Synthesis of 6 -chloroisoquinoline -5 ,8 -diones and [3 ,4-b ] phenazine- 5 .1 2 - diones and evaluation of their cytotoxicity and DNA topoisomerase inhibitory activity
- synthesis a d antifungal activity of new indole conazoles
- Regioselective and Diastereoselective Allylic Amination of Allylic Benzyl Ether using Chlorosulfonyl isocyanate： Asymmetric Total Synthesis of (2R ,5S )-Dihydroxymethyl-(3R ,4R )-dihydroxypyrrolidine
- Identification of Small Ligands that Inhibit the Interaction between Zalpha domain and Z -DN A
- Synthesis and antifungal activity of 4 ,7 -d ioxobenzo [b ]thiophenes
- Antimicrobial and antioxidative effects of Puerariae thunbergiana extractson skin microbial pathogens (II)
- Anxiolytic-like effects of Scrophularia buergeriana in mouse behavior models of anxiety
- Hair levels of cholesterol and 24s-hydroxycholesterol in patients with Alzheimer's disease using GC/MS.
- Preparation and evaluation of IL-5 antisense oligodeoxynucleotides/chitosan complexes
- Determination of Famciclovir in human plasma by high-performance liquid chromatography with ultraviolet detection
- Characterization and Lymphatic Delivery Evaluation of PEGylated Liposomes Containing Cyclosporine-A
- An Animal Model for the Inflammation-Related Colon Carcinogenesis
- Heme Oxygenase-1 in lUmors: Therapeutic Implications
- West Nile Virus: Therapeutic Strategies for Curing Diseases
- Development of Anti-aging Nutraceuticals from Nelumbo nucifera
- Authentication is the Fundamental Work for Standardization of Herbal Medicine
- Representation of Episodic Memory in the Hippocampus
- Osteoporosis and Traditional Chinese Medicine: an Animal Experiment
- Influence Of Anabasine On Catecholamine Release From The Isolated Rat Adrenal Medulla
- Vitexin Attenuates the Level of Hypoxia-Inducible Factor -la in PC12 Cells under Hypoxia
- Alteration of sphingolipid metabolism follow ing fumonisin exposure is a contributing factorfor a decreased Na/K-ATPase activity in LLC -PKl cells
- Lipiodol Solution of 188Re-HDD as a New Therapeutic Agent for Transhepatic Arterial Embolization in Liver Cancer
- Anti-oxidant Activity o f Pimica granatum Extracts ( I )
- Ultraviolet B Induces NF -kB Activation and Cyclooxygenase -2 Expression in Hairless Mouse Skin: Role of IkB K inase-p
- The Effects of chitosan oligosaccharide and squalen on mouse kidney about Candida albicans infection.
- HDAC inhibitors may sustain the self-renewal of mESCs in hypoxic condition by activation of LIF -Stat3 signaling
- 3D -QSAR study of HLE Inhibitory F lavonoids
- Effect of vitamin C on pre - osteoclast and osteoblast differentiation
- Analysis of Arbutin in Whitening Cosmetics
- Formulation of Transdermal Patch System Containing Tulobuterol
- Development of analytical method of Preservatives in oral rinse
- Modulation of Protein Aggregation at Liquid/Liquid Interface by Surfactants
- Bioeqiiivalence study of Fluoxetine HCl 20mg in capsule and tablet formulation.
- Enhanced bioavailability of tamoxifen after oral administration of tamoxifen with quercetin in rats
- Bioequivalence of Yutanal Capsule to Hamal Capsule (Tamsulosin HCl 0.2 mg)
- Factors A ffecting the Apparent Clearance of Tacrolim us in Korean Adult Liver Transplant Patients
- Anti Hepatitis B Therapy
- Induction of Heme oxygenase-1 and Overproduction of Carbon Monoxide Protect Cells from Apoptosis Caused by Peroxynitrite
- Injectable Polyphosphazene gels for the Local Drug Delivery
- Revised Provision for Drug Equivalence
- Biopharmaceutical Application of in situ Polymer Gel
- Combinatorial Effect of 5 -FU and Epigenetic Silencing Repressors in Huanm Colorectal Cancer Cells.
- Analytical Chemometrics for Process Analytical Technology
- Long-functioning cell therapy for treating d iab etes m ellitu s： 1 year study
- Interferon-Y Is Partly Involved in the Neuroprotective Mechanisms of Dietary Restriction.
- Apoptosis-induced cell growth inhibitory effects of a novel compound, AS4O6 in a cervical cancer cell line, SiHa in vitro
- KHUR-12 is a prominent anxiolytic agents.
- Multiplexed liquid assay system profiling for early detection of ovarian cancer
- Synthesis of Seleno-epigallocatechin-3-gallate
- Identification of system ic cell-cycle regulation by Apicindin, a histone deacetylase inhibitor in breast cancer cells through large-scale data analysis of gene expression profiling
- Development and validation of a new liquid chromatographic method with fluorescence detection for gemfibrozil analysis in human plasma
- Induction of GO/Gl cell cycle arrest by 3 -hydroxy -5 -benzoyl-trans -stilbene in HCT 116 human colon cancer cells
- Fenofibrate, an Antihyperlipidaemic Agent, Inhibits Platelet A ggregation and Proliferation of Rat Aortic Vascular Smooth Muscle Cells
- Mortality Effectin C57BL/6 Mouse Bearing Skin Cancer with Boron Compounds and Thermal Neutron Irradiation
- cis -9 ,trans-11-Conjugated linoleic acid down -regulates phorbol ester -induced COX -2 ex p ressio n in h airless m ou se skin： NF -kB and MAPKs as potential targets
- Cytokine Expressions of the Lectin from Serrognathus platymelus castanicolor.
- Hmnulone inhibits expression of COX-2 in phorbol ester -treated mouse skin by blocking activation of IkB K inase and MAPKs
- Effect of daidzein and gen istein on the antioxidant enzym e system in CHO cells.
- Electrospun PLLA-Chitossin Composite Nanofibrous Membrane for Guided Tissue Regeneration
- Total Synthesis of (+ )-Lactacystin
- Nitric Oxide Inhibitory Activities of seven Phenolic Compounds from the fruits of Actinidia arguta
- Ikaros. Transcription Factor, R egulates inducible Nitric Oxide Synthase Gene Expression through Chromatin Remodeling
- Activation of Neuroglia in the CNS Diseases
- The Wnt/P-Catenin and Ras-ERK Pahtway Interact in Cellular Transformaton
- Antidiabetic activity of Grape-Ginsengin Streptozotocin -induced diabeticrats
- The generation of soluble RANK protein using mammalian cell culture system
- Inhibitory effect of benzoxathiolone LYR -64 on expression of inflammatory mediators in LPS -stimulated macrophages RAW 264 .7
- 15 -Deoxy-A 12,14-Prostaglandin J2 Upregulates Heme Oxygenase-1 and VEGF through A ctivation of NF -E 2 -Related Factor 2 (Nrf2) in Human Breast Cancer Cells
- Enhanced Absorption after Oral Administration of Insulin
- Effect of Verapamil on the Modulation of Multi-drug Resistance and Intracellular Accumulation of a Novel Anthracycline in Hepatocarcinoma Cell Lines.
- A ntiplatelet Activity of 15 ,16 - dihydrotanshinone I. One of the Major Ingredients of Salviae Miltiorrhiza Bunge (Dansham ), and its Possible Mechanism s of Action
- Inhibitory Effect of Phthalates on Tamoxifen-induced Apoptosis
- Simultaneous Chiral Separation of Multiple p-Blockers by Capillary Electrophoresis in Reversed Polarity Mode
- Structure-activity relationship of indirubin derivatives on HL -6 0 leukemia cell differentiation
- Characterization of Cytochrome P 450 Enzymes and -Glycoprotein Involved in the Metabolism and Transport of a New Anti-an giogen ic Agent KR -31831
- Simultaneous analysis of indoloquinazoline and quinolone alkaloids in Evodiae Fructus by highperformance liquid chromatography^lectrospray tandem mass spectrometry
- Phospholipase D1 and 2 are regulated by serin e/threonine protein k inases in RBL-2H3 mast cells
- Gas Chromatographic Profiling Analysis of Catecholamine Neurotransmitters and Polyamines for Clinical Applications to Neurological Disorders
- Determ ination of Doxazosin in human plasma by h igh-perform ance liquid chrom atography with FLD detection
- A novel arsenic compound, As406 attenuates 3 -methylcholanthrene toxicity in human keratin ocytes by decreasin gcytochrome P4501A 1 expression
- Redox-Sensitive Transcription Factors in Cellular Defense Against Proinflammatory and Prooxidative Injuries
- The Shigella Flexneri Effector OspG Interferes with Innate Immune Responses by Targeting Ubiquitin-Conjugating Enzymes
- Differential Genomic Responses to Hypoxic Preconditioning and Hypoxic-ischemic Insult in the N eonatal Rat Brain： Identification of Potential Neuroprotective Candidates for Ischemic Stroke
- Qualitative estimation of major constituents of Sopung-San using U V -fingerprint and ES -LC -MS -MS
- Inhibition of Inflammatory Response by CBPharm -001 in UVB -irradiated H uman Fibroblast Cells and Lipopolysaccharide -induced RAW 264.7 Cells.
- Study on the Current Status and Future Improvement of Pharmaceutical Industry—Based Medical Information in Korea
- Comparative enantiomer separation for N-FMOC protected amino acids and their esters on immobilized and coated type chiral stationary phases derived from amylose tris(3,5- dimethylphenylcarbamate)
- Molecular modeling of novel human topoisomerase I inhibitors
- Current Status of Drug Master Files (DMF)
- In vitro Studies on the Immunosuppressive Mechanism of Recom binant CTLA4Ig from Transgenic Rice Cells
- Folate-conjugated heparin-lithocholic acid derivates induce apoptosis in human oral carcinoma KB cells
- Effect of Catalpalactone on Dopamine Content and L -DOPA -Induced Cytotoxicity in PC12 Cells
- Depurination reaction of adenin e-based nucleoside and calf-thymiis DNA with 2-bromopropane at physiological condition, and an alysis of the depurinated products using HPLC and LC/MS/MS
- Macrophage-colony Stimulating Factor Enhances MHC -restricted Presen tation of Exogenous Antigen in DC2.4 and BM -derived Dendritic Cells
- Role of glutathione peroxid ase in the neurotoxicity and dependence induced by methamphetamine.
- Induction of phase II enzyme gene expression by zerumbone derivatives in Hepalclc7 cells
- Studies on the evaluation of efficacy of functional cosmetics-E fficacy evaluation of the w hitening cosmetics using cell signalling
- L iposome - encapsulated melatonin atteenuates kainate -induced neurotoxicity via activation of melatonin MT2 receptor in mice
- Neuroprotective effect of meso-dihydroguaiaretic acid on staurosporine induced neurotoxicity in primary rat cortical cells
- Flexible docking of inhibitors into dihydrofolate reductase using QXP and Flex iDock
- Inhibitory mechanism of benzoxathiolone LYR-64 on iNOS expressionin IFN -gamma-stimulated macrophages RAW 264 .7
- The Methanol Extract from Artemisia Asiatic Naskapi Induces Gi Phase Arrest in A 172 Human Glioma Cells
- Bioinformatic Properties of the Earthworm Eisenia fetida derived Lumbrokinase 1
- A nticancer Activities and Structure-Activity Relationships of Novel Antimicrobial Undecapeptides Derived from Gaegurin 5
- Stilbenoid-induced Apoptosis Is M ediated by p38 MAPK and PI3K/Akt Pathway.
- Protective effect of the extract of Wasabia japonica on oxidative stress induced cell death
- A Famesyl Protein Transferase Inhibitory Compound from Centipeda minima
- Synthesis of Diacetoxy Acetal Derivatives of Santonin and Their Enhancing Effects on HL-60 Leukemia Cell Differentiation
참고문헌
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!