한국인 연소성개방각녹내장 환자에서 섬유주절제술의 장기 성적

• 영문명: Long-Term Outcomes of Trabeculectomy in Korean Patients with Juvenile Open-Angle Glaucoma
• 발행기관: 대한안과학회
• 저자명: 오은규 이은지 정진욱 김석환 김태우 박기호 김동명,Eun Kyu Oh, MD, Eun Ji Lee, MD, Jin Wook Jeoung, MD, Seok Hwan Kim, MD,Tae-Woo Kim, MD, PhD, Ki Ho Park, MD, PhD, Dong Myoung Kim, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number2, 252~260쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.02.15

영문 초록

Purpose: To evaluate the outcomes and prognostic factors of trabeculectomy with mitomycin C in Korean patients with juvenile open-angle glaucoma (JOAG). Methods: A retrospective review was performed on 29 eyes with JOAG who had undergone trabeculectomy between January 2004 and January 2013. Intraocular pressure (IOP) and postoperative complications were monitored at 1 day preoperatively, at 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months postoperatively, and at final follow-up after postoperative 18 months. Surgical success was defined as a final IOP of <21 mm Hg or <80% of preoperative IOP, regardless of the use of anti-glaucoma medication. Prognostic factors for surgical success or failure were analyzed by the Cox proportional hazards model. Results: Mean (± standard deviation) age at trabeculectomy was 24.6 (± 8.9) years, and mean follow-up period was 24.3 (± 20.8) months. The overall success rate was 82.8% at final follow-up. The Kaplan-Meier cumulative probabilities of surgical success were 100% at 1 year, 87.4% at 2 years, and 78.7% at 3 years postoperatively. The Cox proportional hazards model failed to determine any significant factors that were associated with surgical failure. The three most frequent postoperative complications were immediately postoperative hypotony (n = 19, 65.5%), hypotony maculopathy (n = 8, 27.6%), and encapsulated bleb (n = 8, 27.6%), most of which were resolved after a minor procedure or observation. Two of 8 eyes with encapsulated bleb required a second surgery. There were no vision-threatening severe complications. Conclusions: Trabeculectomy with MMC may be an effective treatment in Korean JOAG patients. J Korean Ophthalmol Soc 2014;55(2):252-260

키워드

Juvenile open-angle glaucoma, Prognostic factor, Surgical outcomes, Trabeculectomy