유리체강내 트리암시놀론 주입술로 호전된 임신 중 발생한 보그트-고야나기-하라다 병 1예

• 영문명: Vogt-Koyanagi-Harada Disease in a Pregnant Patient Successfully Treated with Intravitreal Triamcinolone Injection
• 발행기관: 대한안과학회
• 저자명: 곽현덕 임성협 김현웅 윤일한 이호영,Hyun Duck Kwak, MD,, Sung Hyup Lim, MD,, Hyung Woong Kim, MD, PhD,Il Han Yun, MD, PhD, Ho Young Lee, MD,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number10, 1621~1625쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.10.15

영문 초록

Purpose: To report a case of Vogt-Koyanagi-Harada (VKH) disease in a pregnant patient treated with intravitreal triamcinolone injection. Case summary: A 21-year-old female in the 19th week of gestation presented with bilateral blurring of vision associated with mild headache and tinnitus. Her initial best corrected visual acuity was 0.15 in the right eye and 0.3 in the left eye. Multiple serous retinal detachment and anterior chamber inflammation were observed, and VKH disease was diagnosed. Because of her pregnancy, the patient did not want high-dose systemic prednisolone therapy which may cause an abortion or low birth weight infant when used in a pregnant patient. Therefore, an intravitreal triamcinolone (4 mg/0.1 ml) injection was given in the right eye and topical steroid eye drops were used in the left eye. After 1 day, serous retinal detachment was significantly decreased and anterior chamber inflammation disappeared in the right eye. After 1 week, no serous retinal detachment was observed. In the left eye, serous retinal detachment was decreased after using steroid eye drops. After 10 days, serous retinal detachment disappeared but anterior chamber inflammation was still observed. After 1 month, best corrected visual acuity was 1.0 in both eyes and serous retinal detachment had not recurred. On follow-up, VKH disease had not recurred and a healthy normal weight infant was delivered. Conclusions: Intravitreal triamcinolone injection is an effective and safe treatment for VKH disease in pregnant women.

키워드

Intravitreal triamcinolone injection, Pregnancy, Vogt-Koyanagi-Harada disease