알파1-교감신경길항제가 수정체유화술에 미치는 영향

• 영문명: The Effect of α1 -Adrenergic Blocker on Phacoemulsification
• 발행기관: 대한안과학회
• 저자명: 김은경 정성근 백남호,Eun Kyoung Kim, MD, Sung Kun Chung, MD, PhD, Nam Ho Baek, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number2, 256~261쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.02.15

영문 초록

Purpose: To evaluate the influence of α1-adrenergic blocker on phacoemulsification and the preventive effect of adrenergic blocker (AB) cessation before cataract surgery. Methods: A prospective study was performed involving 92 eyes of 60 patients undergoing cataract surgery. Cases were divided into three groups: the use of α1AB with discontinuance before surgery (32 eyes), the use of α1AB with no discontinuance before surgery before surgery (31 eyes), and eyes not treated with α1AB (29 eyes). Clinical measurements and intraoperative parameters were compared among the three groups. Results: Preoperative maximum pupil diameters of patients treated with α1AB were smaller than those of patients not administered α1AB (p = 0.027 and p = 0.018, respectively). The incidence of IFIS in the patients using of α1AB with discontinuance before surgery was 6.25%, and that in the patients using of α1AB with no discontinuance before surgery was 6.45%. There was no IFIS outbreak in the patients not using of α1AB. We noted no significant differences in absolute phaco time during phacoemulsification (p = 0.207) or in the three-month postoperative best corrected visual acuities among the three groups (p = 0.189). Conclusions: Importantly, there appears to be a significant correlation between α1AB and the development of IFIS. To prevent complications of IFIS, surgeons should be vigilant in identifying patients taking α1AB, checking the degree of preoperative pupil dilatation and anticipating intraoperative difficulties. In addition, appropriate modifications should be made to the surgical strategy. Furthermore there was no benefit to discontinuing α1AB treatment before cataract surgery in the prevention of IFIS. J Korean Ophthalmol Soc 2012;53(2):256-261

키워드

α1-adrenergic blocker, Intraoperative floppy iris syndrome, Phacoemulsification