생체 내 분해 콜라겐기질을 이용한 섬유주절제술의 임상적 소견 및 임상 효과에 대한 분석

• 영문명: The Analysis of the Clinical Findings and Effects of Biodegradable Collagen Matrix in Trabeculectomy
• 발행기관: 대한안과학회
• 저자명: 이승주 우제문 민정기 기창원 임진호,Sung Ju Lee, MD, Je Moon Woo, MD, PhD, Jung Kee Min, MD, Chang Won Kee, MD, PhD, Jin Ho Yim, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number2, 297~305쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.02.15

영문 초록

Purpose: To observe the effects of biodegradable collagen matrix (OculusGenTM) on filtering bleb formation and maintenance and to investigate its clinical effects and usefulness in trabeculectomy. Methods: Ophthalmologic examinations were preformed 1 day, 2 weeks, 1 month, 2 months, 3 months, 6 months, and 12 months postoperatively in the case and control groups. The clinical findings of the filtering bleb were observed, and the clinical effects measured by mean intraocular pressure and complications were evaluated in both groups. Results: The success rates were 76% in the case group and 88% in the control group, and there were no significant differences between the case and control groups. In the case group, postoperative conjunctival injection persisted for more than 1 month with increasing severity, while ultrasound biomicroscopy revealed increased echogenicity of the subconjuctival and tenon tissue with no definite space-occupying effect. Conclusions: Trabeculectomy utilizing collagen matrix showed similar clinical results compared to the current traditional trabeculectomy; slit-lamp and ultrasound biomicroscopy findings did not reveal any advantageous changes to filtering bleb function. J Korean Ophthalmol Soc 2012;53(2):297-305

키워드

Biodegradable collagen matrix, Glaucoma, Intraocular pressure, Trabeculectomy