펨토초 레이저를 이용한 데스메막박리 각막내피층판 이식술의 장기 임상경과

• 영문명: Long-term Clinical Outcomes of Femtosecond LASER-Assisted Descemet’s Stripping Endothelial Keratoplasty
• 발행기관: 대한안과학회
• 저자명: 문병길 김재형 이주은 김명준 김재용 차흥원,Byung Gil Moon, MD, Jae Hyung Kim, MD, Joo Eun Lee, MD, Myoung Joon Kim, MD, Jae Yong Kim, MD, PhD, Hungwon Tchah, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume52,number6, 679~689쪽, 전체 11쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2011.06.15

영문 초록

Purpose: To evaluate the long-term clinical outcomes of femtosecond LASER-assisted Descemet’s stripping endothelial keratoplasty (DSEK). Methods: The clinical results of endothelial keratopathy from 11 consecutive patients who were followed up for at least 12 months after femtosecond LASER-assisted DSEK were retrospectively analyzed. The best corrected visual acuities (BCVA), manifest refractions, intraocular pressures, and perioperative complications were evaluated preoperatively and up to 24 months after the femtosecond LASER-assisted DSEK. Results: The average follow-up period was 18 months. Postoperative visual acuity had significantly improved from 1.26 (logMAR) to 0.80 (logMAR) at 3 months (p < 0.05) and this change was maintained during postoperative follow-up. All eyes underwent successful transplantation and the donor discs were well-attached. The mean endothelial cell density continued to decrease during the follow-up period. The donor-recipient stromal interface was the area where varying degree of haziness and birefringent particles were found. Conclusions: The femtosecond LASER-assisted DSEK was effective in creating an endothelial donor disc which resulted in rapid visual recovery and low surgically-induced astigmatism. However, the operation caused rapid decrease in endothelial cell density which requires continuing further consideration by the physician. J Korean Ophthalmol Soc 2011;52(6):679-689

키워드

Anterior segment optical coherent tomography, Confocal microscopy, Femtosecond LASER-assisted Descetmet’s stripping endothelial keratoplasty