스펙트럼 영역 빛간섭단층촬영기를 이용한 근시 정도에 따른 황반 구조의 정량적 분석

• 영문명: Use of Spectral-Domain Optical Coherence Tomography to Analyze Macular Thickness According to Refractive Error
• 발행기관: 대한안과학회
• 저자명: 김승훈 박주연 박태관 온영훈,Seung Hoon Kim, MD, Joo Youn Park, MD, Tae Kwann Park, MD, PhD, Young-Hoon Ohn, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume52,number11, 1286~1295쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2011.11.15

영문 초록

Purpose: To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). Methods: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. Results: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). Conclusions: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes. J Korean Ophthalmol Soc 2011;52(11):1286-1295

키워드

Macula, Macular thickness, Myopia, Refractive error, Spectral-domain optical coherence tomography