맥락막신생혈관이 있는 환자에서 루센티스 안내주사 후 발생한 황반원공

• 영문명: Macular Hole Following Intravitreal Ranibizumab Injections for Choroidal Neovascularization
• 발행기관: 대한안과학회
• 저자명: 조영준 김경남 이종은 김정열,Young Joon Jo, MD,, Kyoung Nam Kim, MD, Jong Eun Lee, MD,, Jung Yeul Kim, MD,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume51,number5, 774~778쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.05.15

영문 초록

Purpose: To report a case of macular hole following intravitreal ranibizumab injection in choroidal neovascularization associated with age-related macular degeneration. Case summary: A 73-year-old man was referred for a sudden decline in vision in his right eye. The best corrected visual acuity was 0.15 in the right eye and 0.9 in the left eye. There was a choroidal neovascularization associated with subretinal hemorrhage in the right eye. Optical coherence tomogram (OCT) showed subretinal hemorrhage and pigment retinal epithelium detachment in the right eye. The patient received intravitreal ranibizumab injection. Four weeks after the initial treatment, the best corrected visual acuity of the right eye was improved to 0.3. The patient received a second intravitreal ranibizumab injection. Four weeks after the second injection, the patient presented with further decreased vision in his right eye, with a best corrected visual acuity of 0.02. Although the fundus examination was indistinct, OCT confirmed the presence of a full thickness macular hole. The patient received a third intravitreal ranibizumab injection. Four weeks after receiving the third injection, the patient underwent pars plana vitrectomy with internal limiting membrane peeling and fluid-gas exchange. Four months later, the macula hole was closed completely and visual acuity was 0.1. Conclusions: Although it is rare, intravitreal ranibizumab injection in the treatment of choroidal neovascularization secondary to age-related macular degeneration may cause complicated by a macular hole. J Korean Ophthalmol Soc 2010;51(5):774-778

키워드

Age related macular degeneration, Choroidal neovascularization, Macula hole, Ranibizumab