토끼에서 여러 방법을 이용한 무봉합 뒤고정술의 효과

• 영문명: The Effects of Sutureless Faden Operation With Several Materials in Rabbit Models
• 발행기관: 대한안과학회
• 저자명: 서정훈 이성준 이옥준 최미영,Jeong Hun Seo, MD, Seong Jun Lee, MD, Ok Jun Lee, MD, Mi Young Choi, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number4, 603~611쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.04.30

영문 초록

Purpose: To investigate the effects of sutureless faden operation to eliminate suture-related perioperative risks in a rabbit model. Methods: Twenty-eighty superior recti muscles of 14 rabbits were subjected to faden operation, at a distance of 6 mm from the insertion of the muscle. They were divided into four groups of 7 muscles each: group A, Beriplast-P ; group B, BardⓇ mesh (12×2 mm); group C, SurgiproⓇ mesh (6×2 mm); group D, SurgiproⓇ mesh (6×6 mm). Rabbits were sacrificed and the eyes were enucleated. The operative field was examined upon dissection, 4 weeks after the surgery. Histopathologic sections were examined for the degree (grade 0 to 4) of inflammation, fibrosis, atrophy and/or degeneration of muscle fiber. Results: Grossly, there was a mild adhesion at the myopexy site in group A, while there was greater adhesion at the myopexy site in groups B, C and D. Group B produced a pronounced adhesion, and the mesh firmly adhered to the sclera as well as to adjacent tissue. Upon histologic examination, group A showed a mild inflammatory reaction and fibrosis, whereas groups B and D showed a moderate inflammatory reaction and fibrosis. The degree of fibrosis in group D was more severe than that in group A (p<0.008), and there was no statistical significance among the other groups (p>0.05). There was atrophy and degeneration in the muscle fiber in all groups, with the exception of group D. Conclusions: In the rabbit model, 6×6 mm sized SurgiproⓇ mesh may be the best material in sutureless faden operation. J Korean Ophthalmol Soc 2009;50(4):603-611

키워드

BardⓇ mesh, Beriplast-P Ⓡ Fadenoperation, SurgiproⓇ mesh, Sutureless strabismus surgery