굴절교정레이저각막절제술 10년 후 각막조직의 공초점현미경 소견

• 영문명: Confocal Microscopic Changes in the Cornea 10 Years After Photorefractive Keratectomy
• 발행기관: 대한안과학회
• 저자명: 신민규 구기홍 이종수,Min Kyu Shin, MD, Gi Hong Koo, MD, Jong Soo Lee, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number2, 303~307쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.02.15

영문 초록

Purpose: The present study compares, using a new generation high‐resolution in vivo confocal microscope, the corneas of patients who underwent photorefractive keratectomy (PRK) 10 years previously with those of healthy persons. Case Summary: A confocal microscope (Confoscan 4.0, Fortune Technology, Italy) was used to get the data from healthy volunteers and patients. Corneal cross‐sectional images of the epithelium, Bowman's layer, stromal layer (anterior, middle and posterior keratocyte), Descemet's membrane, and endothelium were compared. In PRK corneas, the superficial epithelium was nearly intact and the subbasal nerve plexus was visible, but some hyperreflective areas were also found in the nerve plexus. Because of the absence of the Bowman's layer, some ECM and keratocytes were visualized in their optical section. Although anterior keratocytes showed uneven distribution with less cellularity, middle and posterior keratocytes looked unaffected. Likewise, there were no differences in the endothelium between the two groups. Conclusions: Ten years after PRK, the subbasal nerve plexus and anterior keratocytes showed histologic changes after corneal wound recovery.

키워드

Confocal microscopy, Photorefractive keratectomy