단백질 S 결핍 환자에서 발생한 망막중심동맥폐쇄

• 영문명: Central Retinal Artery Obstruction in Protein S Deficiency
• 발행기관: 대한안과학회
• 저자명: 이성복 윤용준 김정열,Sung Bok Lee, M.D.,, Yong Jun Yun, M.D., Jung Yeul Kim, M.D.,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume49,number12, 2017~2020쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.12.15

영문 초록

Purpose: To report a case of central retinal artery obstruction (CRAO) caused by protein S deficiency. Case summary: A 36-year-old man presented with acutely reduced visual acuity in the right eye. The patient had no other diseases such as diabetes mellitus or hypertension. The visual acuity was 20/20 in the right eye and light perception in the left eye. Afferent pupillary defect was observed in theleft eye. Fundus examination showed diffuse retinal opacification and a cherry-red spot at the macula. Thus the patient was diagnosed with CRAO in the left eye. There were no abnormal findings on routine hematologic tests including blood coagulation test. Protein C activity, antithrombin III activation, anticardiolipin antibody were within normal limits but protein S activity was decreased. Thus, the patient was diagnosed with CRAO with protein S deficiency. Conclusions: Coagulation factors such as protein S need to be measuredin cases of CRAO in young patients without medical problems.

키워드

Central retinal artery obstruction, Hypercoagulable state, Protein S