치료가 잘 되지 않는 공막염에서 인플릭시맙(infliximab)의 효과 1예 보고

• 영문명: A Case Report of Intractable Scleritis Effectively Treated with Infliximab
• 발행기관: 대한안과학회
• 저자명: 김동현 위원량 이진학 김미금,Dong Hyun Kim, M.D.,, Won Ryng Wee, M.D.,, Jin Hak Lee, M.D.,, Mee Kum Kim, M.D.,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume49,number10, 1690~1695쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.10.15

영문 초록

Purpose: To report a case of a patient with intractable scleritis with conventional immunosuppressive therapy who showed effective treatment with infliximab. Case summary: A 71-year-old man presented with orbital cellulitis and diffuse anterior scleritis of his left eye. Although orbital cellulites showed remission with topical and systemic antibiotics, scleritis persisted despite a combination therapy of immunosuppressive agents (cyclosporin, mycophenolate, prednisolone) for 1 month. Finally, he was given infliximab (5 mg/kg) intravenously three times at 2-week intervals, after which ocular pain, chemosis, conjunctival injection, and sclera thickening considerably reduced, and scleritis completely remitted. Conclusions: The administration of Infliximab seems to be an effective therapy in patients with intractable scleritis undergoing conventional therapy. J Korean Ophthalmol Soc 2008;49(10):1690-1695

키워드

Infliximab, Scleritis, TNF-a