임산부에서 시력저하로 발견된 림프구성 뇌하수체염 1예

• 영문명: A Case of Lymphocytic Hypophysitis during Pregnancy
• 발행기관: 대한안과학회
• 저자명: 김상우 권정도 박도훈,Sang Woo Kim, M.D., Jung Do Kwon, M.D., Do Hoon Park, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number7, 1183~1188쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.07.31

영문 초록

Purpose: To report a rare case of lymphocytic hypophysitis in a 31-year-old woman who presented with gradually progressive bilateral visual loss during the third trimester of pregnancy. Methods: Ophthalmologic examination revealed best corrected visual acuity of 0.02 OD and counting fingers at 20 cm OS. Pupil examination revealed no relative afferent pupillary defect in either eye and intraocular pressure was normal in both eyes. A visual field test revealed nearly total visual defect sparing superotemporal area OD and total defect OS. An MRI of the head was performed. Results: At the time of transsphenoidal surgery following the patient`s delivery, a frozen biopsy of the lesion revealed diffuse lymphocytic infilteration and fibrosis of the pituitary gland consistent with the diagnosis of lymphocytic hypophysitis. Postoperatively the patient was treated for hypopituitarism. At 5 weeks postoperative, her best corrected visual acuity was 1.0 OU, and visual field defects resolved in both eyes. On follow-up by telephone for postoperative 7 months, the patient remained visually asymptomatic. Conclusions: The clinical presentation of lymphocytic hypophysitis may mimic pituitary adenoma, lymphoma, germinoma, and histiocytosis. The diagnosis should be suspected in any pregnant or postpartum patient with an intrasellar or suprasellar mass.

키워드

Lymphocytic hypophysitis, Pituitary adenoma, Pregnancy