정상안압녹내장 환자의 망막신경섬유층 두께와 시야와의 상관관계

• 영문명: Correlation between Retinal Nerve Fiber Layer Thickness and Visual Field in Normal Tension Glaucoma Patients
• 발행기관: 대한안과학회
• 저자명: 우성욱 최혁원 김재석 이주화,Sung Wook Woo, M.D., Hyuck Won Choi, M.D., Jae Suk Kim, M.D., Joo Hwa Lee, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number10, 1613~1622쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.10.31

영문 초록

Purpose: To determine the correlation between retinal nerve fiber layer (RNFL) thickness and visual field defect for early detection of normal tension glaucoma (NTG). Methods: Sixty eyes newly diagnosed with NTG and 50 normal eyes were analyzed by optical coherence tomography and a short wave length automated perimetry test. The relationship between RNFL, divided into 12 areas, and visual field, divided into 21 areas, were analyzed. Results: Sixty eyes that revealed visual field defect by SWAP showed thinning of the RNFL. OCT sectors 6-o`clock, 7-o`clock, and 8-o`clock (inferior and inferotemporal) and SWAP visual field zones 13, 14, 15 and 16 (superior paracentral, arcuate areas, and the nasal step) were the most frequently damaged. The strongest associations were between the inferior and inferior temporal RNFL sectors 6, 7, and 8-o`clock and the superior nasal/arcuate visual field zones 13, 14, and 15 (R2 range=15.9-34.6%, all p<0.05). Conclusions: A combination of these two methods may be helpful for the early detection of NTG.

키워드

Normal tension glaucoma, Optical coherence tomography, Retinal nerve fiber layer thickness, Short wavelength automated perimetry, Visual field defect