연령관련황반변성에 의한 맥락막하신생혈관에서 광역학치료와 유리체강내 스테로이드주입술의 치료효과

• 영문명: Effect of Photodynamic Therapy and Intravitreal Triamcinolone Acetonide on Choroidal Neovascularization in Age-related Macular Degeneration
• 발행기관: 대한안과학회
• 저자명: 오현섭 노미인 오상준 이성철 이원영 권오웅,Hyun-Sub Oh, M.D., Mi-In Roh, M.D., Sang-Joon Oh, M.D., Sung-Chul Lee, M.D., Won-Young Lee, M.D., Oh-Woong Kwon, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number8, 1321~1327쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.08.31

영문 초록

Purpose: To evaluate the safety and visual outcome of intravitreal triamcinolone acetonide combined with photodynamic therapy for subfoveal choroidal neovascularization in patients with age-related macular degeneration. Methods: We evaluated 32 eyes of 32 patients with choroidal neovascularization due to age-related macular degeneration. The study group received photodynamic therapy and intravitreal triamcinolone acetonide (combined group), while the control group received photodynamic therapy only (PDT group). Results: Three months after treatment, no difference was detected between the two groups in visual acuity changes (p>0.05), but the leakage in fluorescein angiography and macular edema in optical coherent tomography decreased (p<0.05) in the combined group. The retreatment rate in the combined group (6.0%) after 3 months was lower than that of the PDT group (53.3%). Conclusions: Photodynamic therapy with intravitreal triamcinolone acetonide to choroidal neovascularization reduced the retreatment rate at 3 months significantly. These results may have been be due to the short-term anti-inflammatory effect of steroids.

키워드

Age-related macular degeneration, Choroidal neovascularization, Intravitreal triamcinolone acetonide, Photodynamic therapy