유두상 갑상선암의 양측성과 관련된 임상병리학적 인자와 수술 전 초음파 검사의 유용성

• 영문명: Bilaterality of Papillary Thyroid Carcinoma: Analysis of Clinicopathologic Factors and the Value of Preoperative Ultrasonography
• 발행기관: 대한내분비외과학회
• 저자명: 이희승 곽범석 김연대 김홍용 박영진 백용해 오민구 최원용 Hee Seung Lee M.D. Beom Seok Kwak M.D. Yeon Dae Kim M.D. Hong Yong Kim M.D. Young Jin Park M.D. Yong Hae Baik M.D. Min Gu Oh M.D. and Won Yong Choi M.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』9권2호, 85~89쪽, 전체 5쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2009.06.30

영문 초록

Purpose: Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. The extent of the initial surgical treatment for PTC is still controversial and the bilaterality of PTC is an important factor for determining the extent of surgical resection. The aim of this study was to analyze clinicopathologic factors and the value of preoperative ultrasonography (PU) for bilateral tumor. Methods: We retrospectively reviewed clinicopathologic factors and PU findings of 91 patients who underwent total thyroidectomy for PTC at the Dongguk University Ilsan Hospital from January 2006 to April 2009. Results: Of the 91 patients, 28 (30.7%) had bilateral PTC in postoperative pathology. Of these 28 patients, only 18 patients (64.3%) were checked for bilateral PTC by PU findings and fine needle aspiration cytology. Sensitivity and specificity for bilaterality of PTC were 64.3% and 85.7%, respectively. The presence of benign nodules or malignant nodules in the same lobe in PU (P=0.008) and post-operative pathology (P=0.014) were statistically correlated with bilaterality. Conclusion: For the surgical care of PTC, bilaterality must always be considered, even though the tumor is diagnosed unilateral small PTC. PU in PTC patients has limited diagnostic value for bilateral PTC. (Korean J Endocrine Surg 2009;9:85-89)

키워드

유두상 갑상선암, 양측성, 초음파 소견, 임상병리학적 인자,Papillary thyroid carcinoma, Bilaterality, Ultrasonographic findings, Clinicopathologic factors