해당화 지하부의 혈청 Cholesterol치 저하효과

• 영문명: The Serum Cholesterol Level Lowering Effect from the Underground Parts of Rosa rugosa
• 발행기관: 대한약학회
• 저자명: 양한석(Han Suk Young) 박종철(Jong Cheol Park) 최재수(Jae Sue Choi) 정해영(Hae Young Chung)
• 간행물 정보: 『약학회지』제31권 제6호 (1987년), 394~398쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1987.12.30

영문 초록

The present paper describes the serum cholesterol level lowering effect of the underground parts of Rosa rugosa(Rosaceae) which have been used in a folkloric medicine for treating diabetics. The methanol extract was shown to lower the serum lipid level against the normal and 1% cholesterol and 0.5% cholic acid diet feeding to rats, respectively. When various fractions prepared from the above methanol extract was administered, the ethyl acetate-soluble fractions lowered the serum cholesterol level most remarkably. And when (+)-catechin from the ethyl acetate-soluble fractions was only administered to them, the serum cholesterol level was significantly lowered to 260 +/- 9.3mg/dl, the decrease of 17% for the control group. Therefore, it is suggested that (+)-catechin is one of the active principles of this plant.