납중독에 있어서 delta-Aminolevulinic Acid Dehydratase 활성에 미치는 Ascorbic Acid 및 Methionine의 효과에 관한 연구

• 영문명: The Influence of Ascorbic Acid and Methionine on the delta-Aminolevulinic Acid Dehydratase Activity in Lead Poisoning.
• 발행기관: 대한약학회
• 저자명: 윤혜정(Hae Chung Yun)
• 간행물 정보: 『약학회지』제19권 제1호 (1975년), 21~29쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1975.03.31

영문 초록

the activity of delta-aminolevulinic acid debydratase(ALAD) in red cell of rabbit inhibited by addition of Pb(Ac)2 was recovered by ascorbic acid and methionine. Although the administration of Pb(AC)2 (50mg/kg) to rabbit caused to diminish completely the ALAD activity in blood within 2 hr. Pretreatment of ascorbic acid and methionine decreased this inhibitory action. Pretreatment of ascorbic acid also decreased the increment of delta-aminolevulinic acid output in urine by lead poisoning.