GC-FPD를 이용한 염산에페드린 및 그 관련물질의 정량

• 영문명: Determination of Ephedrine Hydrochloride and its Analogs by GC-FPD
• 발행기관: 대한약학회
• 저자명: 박만기(Man Ki Park) 조영현(Yung Hyun Cho) 이용문(Yong Moon Lee) 노일협(Ihl Hyeob Ro)
• 간행물 정보: 『약학회지』제30권 제5호 (1986년), 214~219쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1986.10.30

영문 초록

A gas chromatographic procedure is described for the quantitative analysis of ephedrine hydrochloride, pseudoephedrine hydrochloride and norephedrine hydrochloride in pharmaceutical preparations. The procedure was based upon the determination of thioureas formed from amines and phenylisothiocyanate. The recoveries of ephedrine, pseudoephedrine and norephedrine from pharmaceutical preparations were 100.7 (S.E. 0.9), 99.5 (0.8), 99.1 (0.8) and 99.1% (0.9), respectively. The high accuracy and precision of this assay were inherent in the flame photometric detectors normally used in gas chromatography.