맥동성 초음파가 흰쥐 창상치유에 미치는 조직학적 변화

• 영문명: The Histological Observation of the Effects of Pulsed Ultrasound on Wound Healing of Rats
• 발행기관: 한국전문물리치료학회
• 저자명: 김계엽(Gye-yeop Kim) 김태열(Tae-youl Kim) 나수영(Soo-young Na) 김경윤(Kyung-yoon Kim) 김기도(Gi-do Kim) 김종만(Jong-man Kim)
• 간행물 정보: 『한국전문물리치료학회지』한국전문물리치료학회지 제12권 제1호, 80~90쪽, 전체 11쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2005.03.31

영문 초록

The purpose of this study was to evaluate the effects of pulsed ultrasound on wound healing and observe during the wound healing process the distribution of mast cells according to histopathologic findings. Eighty Sprague Dawley rats which were divided into 4 groups received full thickness skin wounds on the back. Each of the 5 animals was sacrificed immediately and then sacrificed again 1, 3, 6, and 12 days after injury. Specimens from the wounds were removed during healing and routinely processed with a hematoxylin-eosin stain and a toluidine blue stain. The authors then observed the distribution of mast cells under a light microscope. The results of this study were as follows: The rate of wound healing and the length of the wounds of the pulsed ultrasound group Ⅱ was significantly faster than group Ⅰ on day 6 and day 12 (p＜.001). Group m showed the most significant effect after12 days (p＜.001). Group Ⅳ also showed a significant effect at 12 days (p＜.01). A low-intensity ultrasound .5 W/㎠ resulted in a fast healing rate. During the wound healing process mast cells had a tendency to decrease in the acute inflammatory phase. During the wound healing process mast cells were thought to contribute to the healing of the wound.

목차

Abstract

Ⅰ. 서론

Ⅱ. 연구방법

Ⅲ. 결과

Ⅳ. 고찰

Ⅴ. 결론

인용문헌

키워드

Histopathology Mast cell Ultrasound Wound healing