다형성 세망증(Polymorphic Reticulosis)의 방사선 치료 성적

• 영문명: Radiation Therapy Result of Polymorphic Reticulosis
• 발행기관: 대한방사선종양학회
• 저자명: 정은지 (Eun Ji Chung) 김귀언 (Gwi Eon Kim) 박영년 (Young Nyun Park)
• 간행물 정보: 『대한방사선종양학회지』제11권 제1호, 83~90쪽, 전체 8쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1993.06.30

영문 초록

During the period form January, 1975, to June, 1989, one hundred patients with histropathologically proven polymorphic reticulosis in the upper respiratory tract were treated with radiation therapy and the analysis of treatment results was undertaken. One hundred patients (69 males, 31 females) with a mean age of 46 years (range 12-79 years) were presented. Nasal cavity was the most frequent site of involvement (56%), and 44 cases had multifocal sites of involvement. The incidence of cervical lymph node metastasis at initial diagnosis was 24%, Staging was determined by Ann-Arbor classification, retrospectively. The number of patients of stage IE, IIE, IIIE and IVE were 35, 60, 1, and 4, respectively. The overall 5 year actuarial survival rates were 38.4%. The difference in 5 year survival rates between patients with stage IE and IIE, with solitary and multiple, with CR and PR after irradiation were significant statistically. For the analysis of failure patterns, failure sites include the following local failure alone (30/55=54.6%) systemic failure alone (9/55=16.4%), both local and systemic failure (16/55=29.0%). Retrograde slide review was available in 29 cases of PMR with respect to histopathologic bases, and immunohistochemical studies were performed using MT1 and DACO-UCHL-1 as T-cell markers, MB2 as a B-cell marker and alpha-1-antichymotrypsin as a histiocytic markers. All that 29 cases showed characteristic histologic features similar to those of peripheral T-cell lymphoma and showed positive reactio to the T-cell marker. These findings suggest strongly that quite a significant portion of PMR may be in fact T-cell lymphoma.

목차

abstract

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대상 및 방법

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REFERENCES

키워드

PMR (Polymorphic reticulosis) Peripheral T-cell lymphoma Radiation therapy.