학술논문
Decreased Serum Cocaine- and Amphetamine-Regulated Transcript Level in Internet Gaming Disorder
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- 영문명
- 발행기관
- 대한신경정신의학회
- 저자명
- Ara Cho Heejin Lee Dong Huey Cheon So Young Yoo Arom Pyeon Ji-Won Chun Ji Hyun Back Yae Eun Park Dai-Jin Kim Ji Eun Lee Jung-Seok Choi
- 간행물 정보
- 『Psychiatry Investigation』제21권 제7호, 755~761쪽, 전체 7쪽
- 주제분류
- 의약학 > 정신과학
- 파일형태
- 발행일자
- 2024.07.30
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국문 초록
Objective Vulnerability to internet gaming disorder (IGD) has increased as internet gaming continues to grow. Cocaine- and amphetamine-regulated transcript (CART) is a hormone that plays a role in reward, anxiety, and stress. The purpose of this study was to identify the role of CART in the pathophysiology of IGD.
Methods The serum CART levels were measured by enzyme-linked immunosorbent assay, and the associations of the serum CART level with psychological variables were analyzed in patients with IGD (n=31) and healthy controls (HC) (n=42).
Results The serum CART level was significantly lower in the IGD than HC group. The IGD group scored significantly higher than the HC group on the psychological domains of depression, anxiety, the reward response in the Behavioral Activation System and Behavioral Inhibition System. There were no significant correlations between serum CART level and other psychological variables in the IGD group.
Conclusion Our results indicate that a decrease in the expression of the serum CART level is associated with the vulnerability of developing IGD. This study supports the possibility that CART is a biomarker in the pathophysiology of IGD.
Psychiatry Investig 2024;21(7):755-761
영문 초록
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
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