Neuroprotective effects of Moringa oleifera leaf extracts

• 영문명: Neuroprotective effects of Moringa oleifera leaf extracts
• 발행기관: 한국축산식품학회
• 저자명: Hyeong Sang Kim Chang-Ho Jeong Jong-Kwang Lee
• 간행물 정보: 『Food and Life』제2022권 제1호, 19~26쪽, 전체 8쪽
• 주제분류: 농수해양 > 식품과학
• 파일형태: PDF
• 발행일자: 2022.03.31

영문 초록

This study was carried out to evaluation the neuroprotective effects of Moringa oleifera leaf. The polyphenols myricetin and kaempferol were detected in M. oleifera leaf at 5.44 and 1,157.13 mg/100 g, respectively. M. oleifera leaf ethanol extract (MOLE) reduced oxidative stress (%) more than vitamin C did (90.26%) at 100 and 200 μg/mL (p<0.05). MOLE increased cell viability (%) (p<0.05) and similarly to vitamin C (88.36%). Additionally, the lactate dehydrogenase (LDH) release into the medium (%) induced by ascorbic acid (vitamin C) was comparable to that of MOLE at 100 and 200 μg/mL (p>0.05). The antioxidant activities of M. oleifera leaf water extract (MOLW) and MOLE were measured. MOLE showed higher 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging (%) and malondialdehyde inhibition (%) than MOLW did (p<0.05). In conclusion, M. oleifera leaf extracts, especially MOLE could be potential natural neuroprotective agents to substitute synthetic chemicals.

목차

Introduction

Materials and Methods

Results and Discussion

Conclusion

Conflicts of Interest

Acknowledgments

Ethics Approval

Author Contributions

Author Information

References

키워드

neuroprotective effect Moringa oleifera leaf polyphenols antioxidant activity