In vitro induction effects of Commiphora molmo (Myrrh) extracts on cell migration through anti-inflammatory activity

• 영문명: In vitro induction effects of Commiphora molmo (Myrrh) extracts on cell migration through anti-inflammatory activity
• 발행기관: 한국축산식품학회
• 저자명: Hyun Joo Ha Seung-Jae Lee Seon Gyeong Bak Seung Woong Lee Sun Hee Cheong
• 간행물 정보: 『Food and Life』제2020권 제1호, 47~52쪽, 전체 6쪽
• 주제분류: 농수해양 > 식품과학
• 파일형태: PDF
• 발행일자: 2020.03.31

영문 초록

Commiphora molmo (Myrrh) contains various biological activities. However, the underlying molecular mechanisms in cells remain unknown. The purpose of this study was to confirm the efficacy of inhibiting nitric oxide (NO) production induced by lipopolysaccharides (LPS) on J774 macrophage cells of myrrh, and additionally regulatory effects of perform wound healing. Further, vascular endothelial growth factor (VEGF), phosphorylation of signal transducer and activator of transcription3 (p-STAT3) and Janus kinase 2 (p-JAK2) levels in macrophage cells were regulated in the presence of myrrh extract. Based on the above results, myrrh is thought to provide basic data on anti-inflammatory properties through interleukin 6 (IL-6) inhibitory activity and regulatory effects of cell migration.

목차

Introduction

Materials and Methods

Results and Discussion

Conflicts of Interest

Acknowledgments

Ethics Approval

Author Contributions

Author Information

References

키워드

Commiphora molmo (Myrrh) anti-inflammation cell migration wound healing