비만 치료 연구에서 마황의 안전성 분석

• 영문명: Analysis of Safety of Mahuang in Studies for Treatment of Obesity
• 발행기관: 한방비만학회
• 저자명: 조민진(Minjin Cho) 김성하(Sungha Kim) 김호준(Hojun Kim) 송미영(Mi Young Song)
• 간행물 정보: 『대한한방비만학회지』제21권 2호, 95~104쪽, 전체 10쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2021.12.31

영문 초록

Objectives: The purpose of this study is to analyze the adverse events and safety of Mahuang used as anti-obesity treatment in Korean medicine. Methods: PubMed, EMBASE, Cochrane, KoreaMed, Oriental Medicine Advanced Searching Integrated System (OASIS) and SCIENCE-ON were used as searching for randomized controlled trials investigating the safety of Mahuang for treating obesity from January, 2000 to July, 2021. Results: Total 6 studies were included for analyzing. In most studies, heart rate was higher in experimental group than in placebo group with statistically significant difference. Both systolic and diastolic blood pressure had no significant differences between both groups, but systolic blood pressure got lower in experimental group. Most adverse events reported in experimental group were dry mouth, constipation, diarrhea, palpitation and insomnia, but serious adverse events were not reported. Conclusions: This study provides the evidence about the safety of Mahuang for treating obesity. However, increase of heart rate and minor adverse events could be occurred. Further study is needed to confirm the safety of Mahuang.

목차

서론

방법

고찰 및 결론

키워드

Systematic review Meta-analysis Ephedra sinica Safet