대사증후군 개선을 위한 뽕잎, 오디, 누에 분말의 혼합 비율 최적화

• 영문명: Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome
• 발행기관: 한방비만학회
• 저자명: 김민주(Min-Ju Kim) 김현숙(Hyun-Sook Kim) 김애정(Ae-Jung Kim)
• 간행물 정보: 『대한한방비만학회지』제18권 2호, 83~95쪽, 전체 13쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2018.12.31

영문 초록

Objectives: The aim of this study was optimized mixing ratio of mulberry leaf, mulberry fruit, and silkworm for amelioration of the metabolic syndrome by using response surface method (RSM). Methods: Antioxidant, antidiabetic and antihypertensive activities of fifteen mixed powder of mulberry leaf, mulberry fruit, and silkworm by RSM were measured as indicators of metabolic syndrome. Results: The optimal mixing ratio of mulberry leaves, mulberry fruits, and silkworm with the greatest antioxidant, antidiabetic and antihypertensive activities was as follows: 2.5890 of mulberry leaf (A), 0.1222 of mulberry fruit (B), 2.9999 of silkworm (C). At this time, it was predicted that the total polyphenol content was estimated to be 185.51 tannic acid equivalent mg/g, 1, 1-diphenyl-2-picrylhy drazyl radical scavenging activity 84.77%, 1-deoxynojirimycin content 415.66 mg/100 g, α-glucosidase inhibitory activity 64.31%, γ-aminobutyric acid content 267.77 mg/100 g, potassium content 1,899.11 mg/100 g, and angiotensin-converting-enzyme inhibitory activity was estimated to be 73.78%. Conclusions: It was concluded that the significant effect of the mulberry leaf, mulberry fruit, and silkworm on the metabolic syndrome-related biological activity indices (antioxidant activity, antidiabetic activity and antihypertensive activity) was as follows: 2.5890 of mulberry leaf (A), 0.1222 of mulberry fruit (B), 2.9999 of silkworm (C).

목차

서론

재료 및 방법

결과

고찰

결론

키워드

Mulberry leaf Mulberry fruit Silkworm Metabolic syndrome Optimization Response surface methodology (RSM)