The effect of coenzyme Q10 on endothelial function in a young population

• 영문명: The effect of coenzyme Q10 on endothelial function in a young population
• 발행기관: 물리치료재활과학회
• 저자명: Jerrold Petrofsky M. Laymona H. Lee E. Hernandez D. Dequine L. Thorsen R. Lovell J. Andrade
• 간행물 정보: 『Physical Therapy Rehabilitation Science』제1권 제1호, 6~12쪽, 전체 7쪽
• 주제분류: 의약학 > 재활의학
• 파일형태: PDF
• 발행일자: 2012.12.31

영문 초록

Objective: Coenzyme (CoQ10) is an enzymatic co factor used in normal cellular metabolism. Recent evidence shows that in people with heart disease it can reverse endothelial cell damage in the blood vessels. It is also a potent antioxidant. Design: One group pretest-posttest design. Methods: In the present study, endothelial function was evaluated using the response to occlusion and heat before and 2 weeks after administration of CoQ10, 300 mg/day. Thirty Eight subjects, who are physical therapy students, participated in a series of experiments to see if taking 300 mg of CoQ10 daily for 2 weeks would impact resting blood flow in the forearm skin and the blood flow response to 4 minutes of vascular occlusion and the response to local heat (42oC) for 6 minutes. Results: The results showed that, for this population, there was no difference in the response to heat. However, the response to occlusion was improved after administration of CoQ10. Conclusions: It would appear that in a young population CoQ10 has no effect on the nitric oxide vasodilator pathway in skin but does influence other vasodilator pathways.

목차

Introduction

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Discussion

키워드

Blood flow Circulation Flow mediated dilation Q10 Vitamins