체감의이인탕(體減薏苡仁湯)이 비만유도 흰쥐의 체중,지방조직, 혈액변화, leptin과 Uncoupled protein에 미치는 영향

• 영문명: Effects of Chegameyiin-tang extract on the change of the weight, tissue in epididymal fat, blood, leptin and uncoupled protein in visceral fat of obesity rats induced by high
• 발행기관: 한방비만학회
• 저자명: 송재철(Jae Chul Song) 김길수(Kil Su Kim)
• 간행물 정보: 『대한한방비만학회지』제1권 1호, 106~130쪽, 전체 25쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2001.01.31

영문 초록

In Oriental medicine, there has been a theory that the deficiency of the Qi(氣) and the Phlegm(濕)-Damp(痰) bring Obesity. And so a clinically representative herb-medicine of the obesity treatments is Chegameyiin-tang. We observed the effects of Chegameyiin-tang on the fat tissues and what the function of Chegameyiin-tang is. These experimental studies were designed to investigate the effects of Chegameyiin-tang on the weight and lipid metabolism of obesity rats induced by high fat diet. And what is changed in the blood and how the leptin and uncoupled protein is affected. The measurement has been performed on (1) the weight of obese rats fed high fat diet, (2) the average size and number of epididymal fat cells, (3) the total cholesterol, triglyceride, glucose, and free fatty acids in the blood, and (4) the leptin and uncoupled protein in the blood are observed. 1. In the sample group, the weight decrease occured significantly throughout the whole research period than that of control group. 2. In the sample group, epididymal fat weight showed significantly decrease in the 8th and 14th weeks than that of control group. 3. In the sample group, epididymal fat cell size was decreased significantly in the 8th and 14th weeks than that of control group. 4. In the sample group, total cholesterol, triglyceride and glucose increased rather than control group in 8 weeks, those decreased significantly in 14 weeks. 5. In the sample group, free fatty acids and insulin increased rather than control group in 8 weeks, those showed some decrease in 14 weeks. 6. In the sample group, leptin decreased significantly than control group in 8, 14 weeks. Uncoupled protein showed some decrease in 8 weeks, that decreased significantly in 14 weeks.

목차

Ⅰ. 서론

Ⅱ. 연구대상 및 방법

Ⅲ. 결 과

Ⅳ. 고찰

Ⅴ. 결론

참고문헌

키워드

Chegameyiin-tang leptin uncoupled protein obesity high fat diet