지방세포 대사에 미치는 주요 호르몬들의 작용

• 영문명: Major Hormonal Regulations in Obesity and Fat Distribution
• 발행기관: 한방비만학회
• 저자명: 김호준(Ho Jun Kim)
• 간행물 정보: 『대한한방비만학회지』제1권 1호, 1~11쪽, 전체 11쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2001.01.31

영문 초록

Obesity is a metabolic disease associated with multiple hormonal abnormalities. Therefore, obesity management aims at balancing these endocrine malfunctions nowadays. Although many studies proved interactions of hormones related with obesity, there are still lots of controversies. Most of these malfunctions are more pronounced in central, visceral obesity than in peripheral obesity. Recently, it is revealed that a central lesion of endocrine malfunction in human visceral obesity is probably related with a hypersensitivity of hypothalamo-pituitary-adrenal(HPA) axis. Probably associated with this axis, Insulin and cortisol promote lipid accumulation by expressing lipoprotein lipase activity, while sex hormones and growth hormone exert the opposite effects. Also reviewed was thyroid hormone which is closely related with thermogenesis. Serotonin is prescribed as antidepressant and it is applied to some eating disorders. Recently, leptin made in fat deposit also took attentions in terms of regulator of appetite and messenger of sex signal.

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키워드

Obesity Hormone HPA axis fat distribution central obesity