ICR 마우스를 이용한 발효 방풍통성산의 급성독성 연구

• 영문명: A Study on the Acute Toxicity of Fermented Bangpungtongsung-san,Fangfengtongsheng-san Extract in ICR Mice
• 발행기관: 한방비만학회
• 저자명: 이지혜(Ji Hye Lee) 이재훈(Jae Hoon Lee) 엄영란(Young Ran Um) 마진열(Jin Yeul Ma)
• 간행물 정보: 『대한한방비만학회지』제9권 2호, 11~19쪽, 전체 9쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2009.12.31

영문 초록

In this study, we investigated the acute toxicity and safety about fermented Bangpungtongsung-san(Fangfengtongsheng-san) extract. Methods To evaluate the acute toxity and safety, fermented Bangpungtongsung-san (Fangfengtongsheng-san) at the respective doses of 0(control group), 1250, 2500 and 5000 ㎎/㎏ were orally treated to 20 male and 20 female mice. After single administration, we observed survival rates, general toxicity, changes of body weight and autopsy. Results Compared with the control group, we could not find any toxic alteration in all treated groups (1250, 2500 and 5000 ㎎/㎏). Conclusions LD50 of fermented Bangpungtongsung-san(Fangfengtongsheng-san) extract might be over 5000 ㎎/㎏ and it is very safe to ICR mice.

목차

Ⅰ. 서 론

Ⅱ. 대상 및 방법

Ⅲ. 결 과

Ⅳ. 고 찰

Ⅴ. 결 론

Ⅵ. 감사의 말씀

Ⅶ. 참고문헌

키워드

Bangpungtongsung-san Fangfengtongsheng-san Fermentation Acute toxicity Safety LD50