In Vivo Human Lacrimal Gland Imaging Using an Ultrasound Biomicroscopy

• 영문명: In Vivo Human Lacrimal Gland Imaging Using an Ultrasound Biomicroscopy
• 발행기관: 대한안과학회
• 저자명: Chanjoon Park Da Ran Kim Young Chae Yoon SoonWon Yang Woong-Joo Whang Yong-Soo Byun Hyung Bin Hwang Kyung Sun Na Hyun Soo Lee So Hyang Chung Eun Chul Kim Yang Kyung Cho Hyun Seung Kim Ho Sik Hwang
• 간행물 정보: 『The Korean Journal of Ophthalmology』Vol.38 No.3, 227~235쪽, 전체 9쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2024.05.31

국문 초록

Purpose: In the present study, we introduce human lacrimal gland imaging using an ultrasound biomicroscopy (UBM) with a soft cover and show their findings Methods: The representative UBM findings of palpebral lobes in seven subjects (four with non-Sjögren dry eye syndrome, one with Sjögren syndrome, and two healthy subjects) were described in this study. To prolapse the palpebral lobe, the examiner pulled the temporal part of the upper eyelid in the superotemporal direction and directed the subject to look in the inferonasal direction. We scanned the palpebral lobes longitudinally and transversely using UBM. We used an Aviso UBM with a 50 MHz linear probe and ClearScan. Results: In UBM of two healthy subjects, the echogenicity of the lacrimal gland was lower than that of the sclera and homogeneous. But the parenchyma of a patient with Sjögren dry eye syndrome was quite inhomogeneous compared to the healthy subjects. In two patients with dry eye syndrome, we were able to observe some lobules in the parenchyma. We could find excretory ducts running parallel at the surface of the longitudinal section in some subjects. In the longitudinal UBM scan of a subject, we observed a tubular structure at a depth of 1,500 μm that was considered a blood vessel. It ran from the superonasal to the inferotemporal direction. In a subject, we observed a large cyst beneath the conjunctiva. Conclusions: Lacrimal gland imaging using UBM has both advantages of optical coherence tomography and sonography, and could be useful for evaluating dry eye syndrome.

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키워드

Excretory ducts Lacrimal gland Lobules Parenchyma Ultrasound biomicroscopy