Antioxidant activity of 3,5-dicaffeoyl-epi-quinic acid (DEQA) from the halophyte Atriplex gmelinii

• 영문명: Antioxidant activity of 3,5-dicaffeoyl-epi-quinic acid (DEQA) from the halophyte Atriplex gmelinii
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 김호준(Hojun Kim) 강창숙(Chang-Suk Kong) 서영완(Youngwan Seo)
• 간행물 정보: 『한국응용과학기술학회지』제41권 제2호, 447~458쪽, 전체 12쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2024.04.30

국문 초록

In this study, the antioxidizing effect of 2,3-dicaffeoyl-epi-quinic acid (DEQA) was investigated. The antioxidant activity was evaluated by measuring the scavenging effect on DPPH radical and peroxynitrite and the reducing power on ferric ion. DEQA showed a scavenging effect and reducing power comparable to vitamin C used as a positive control. Also, DEQA effectively inhibited production of intracellular reactive oxygen species (ROS) in HT-1080 cells, showing the scavenging ratio of 43.8% even at 10 μM concentration of DEQA after 2 hours in HT-1080 treated with H2O2. In addition to this, DEQA inhibited the production of nitric oxide (NO) very effectively in Raw 264.7 cells. The above results suggest that DEQA has the potential to be developed as a natural antioxidant.

목차

1. Introduction

2. Materials and methods

3. Results and Discussion

4. Conclusion

References

키워드

Halophyte Atriplex gmelinii 2 3-dicaffeoyl-epi-quinic acid (DEQA) Antioxidant Reactive oxygen species (ROS)