갑상선암의 방사성옥소 치료 후 전신 스캔에서 비타민C 용액을 이용한 식도의 위양성 병소 제거에 대한 고찰

• 영문명: An Elimination of False-Positive I-131 Sites in Esophagus for Thyroid Carcinoma; Using Water with Vitamin C Dissolved
• 발행기관: 대한핵의학기술학회
• 저자명: 이승재(Seung Jae Lee) 박훈희(Hoon-Hee Park) 안샤론(Saron Ahn) 조석원(Seok won Cho) 최영숙(Young Sook Choi) 조응혁(Arther Cho) 김재삼(Jae Sam Kim) 이창호(Chang Ho Lee)
• 간행물 정보: 『핵의학기술』Vol.12 No.1, 49~56쪽, 전체 8쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2008.05.30

영문 초록

Purpose: Whole body imaging with radioiodine can detect functioning metastases. Non-physiologic I-131 uptake detected on images usually is interpreted as suggesting functioning thyroid metastases. However, extra-thyroidal I-131 accumulation does not always imply thyroid cancer metastases and has been reported in many circumstances. In order to avoid unnecessary therapeutic interventions it is important to distinguish false-positive sites of I-131 localization. We study here to remove false-positive sites around esophagus region on I-131 whole body imaging in patients who were administrated thyroidectomy. Materials and Methods: From April to August in 2007, we had the patients who had visited our department after they received thyroidectomy due to thyroid cancer. They were given I-131, and performed radioiodine body scan after 41 to 50 hours. Patients were whole-body-scanned for the speed of 8 cm per minute. After that, we took anterior and posterior static images around the patients’ neck measured by 300 thousand counts per image. We selected 44 patients who had hot spots around neck region, we divided the patients into two groups. One group was given 0.5 L of water and the other group was given 0.5 L of water with 1 g of Vitamin C dissolved. The patients were asked to drink the fluid for one minute in sitting position and after that, we measured 300 kilo counts per image again. We compared prior anterior, posterior static images with anterior, posterior images after the patients had water or water that Vitamin C resolved. Results: In using water, both observer 1 and 2 interpreted 6 patients were washed out. In the water with Vitamin C resolved, observer 1 and 2 interpreted 9 and 8 patients were washed out. Observer 1 and 2 interpreted 6 and 5 patients had ‘indeterminate’ when they used water. Both observer 1 and 2 interpreted 6 patients had ‘indeterminate’ when they used water with Vitamin C resolved. When they used water, observer 1 interpreted 10 patients had ‘unchanged’ and observer 2 interpreted 11 patients had ‘unchanged’. Differently, when they used water with vitamin C resolved, observer1 had 8 patients having ‘unchanged’and observer 2 had 9. Conclusion: As a result, by making patients drink 0.5 liter of water which has vitamin C resolved helped getting rid of false-positive sites in esophagus. Therefore, based on this study, we believe that drinking water with vitamin C dissolved is very in terms of reducing false-positive hot spot around the esophagus for the iodine-131 whole body scan.

목차

서론

대상 및 방법

결과

결론

고찰

요약

INTRODUCTION

MATERIALS AND METHODS

RESULTS

CONCLUSION

DISCUSSION

REFERENCES

키워드

Iodine-131 whole body scan Thyroid cancer False-positive iodine-131 sites