한국 전통 된장 및 콩 추출물의 KB 세포에 대한 증식 억제효과

• 영문명: Inhibitory Effects of Doen-jang (Korean Fermented SoybeanPaste) and Soybean Extracts on the Growth of KB Cells
• 발행기관: 한국환경보건학회
• 저자명: 이성림(Sung-Lim Lee) 김종규(Jong-Gyu Kim)
• 간행물 정보: 『1. 한국환경보건학회지』제31권 제5호, 444~450쪽, 전체 7쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2005.10.30

영문 초록

The present study was designed to investigate whether traditional Korean fermented soybean paste (doen-jang) andsoybean extracts have inhibitory effects on the growth of KB cell, an oral epithelioid cancer cell. When KB cell ATCCCCL-17 was cultivated for 48 hours with the addition of 0.5% of the five types of doen-jang extract, the growth of KBcell was inhibited by all types of extract, and ethyl acetate extract showed the highest inhibitory effect. In case of soybeanextract, all types of extract also showed KB cell inhibitory effects, however, generally less than those of doen-jangextract. When ethyl acetate extract of doen-jang was added in different concentrations and KB cell was cultivated for24 hours and 48 hours, strong inhibitory effect began to appear from the concentration of 1.25 mg/ml. Although soybeanextract showed such a tendency, its effect was lower than that of doen-jang extract. These results indicate that doenjangextract has inhibitory effect against KB cell, and particularly ethyl acetate extract has the highest effect. The effectof doen-jang extract might be possibly enhanced by the fermentation of soybeans. It is assumed that doen-jang extractmay be used to develop nontoxic medicines for preventing and treating oral diseases.

목차

Ⅰ. 서론

Ⅱ. 재료 및 방법

Ⅲ. 결과 및 고찰

Ⅳ. 결론

키워드

Doen-jang extract soybean extract KB cell inhibitory effect