Location of Retinal Nerve Fiber Layer Defects in Open-angle Glaucoma and Associated Factors

• 발행기관: 대한안과학회
• 저자명: Han Ul Kim Kyeong Ik Na
• 간행물 정보: 『The Korean Journal of Ophthalmology』Vol.33 No.4, 379~385쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2019.06.30

영문 초록

Purpose: To investigate the location of retinal nerve fiber layer defects (RNFLDs) in open-angle glaucoma and the differences in systemic and ocular factors between superotemporal and inferotemporal RNFLDs. Methods: We performed a retrospective review of the 2008 to 2012 data from the Korea National Health and Nutrition Examination Survey. Subjects aged ≥19 years with an evaluable fundus photograph of at least one eye were enrolled, and open-angle glaucoma was diagnosed according to modified International Society of Geographical and Epidemiological Ophthalmology criteria. In subjects with open-angle glaucoma, locations of RNFLDs were evaluated, and systemic and ocular factors were compared between the bilateral superotemporal RNFLD group and bilateral inferotemporal RNFLD group. Results: A total of 534 subjects had open-angle glaucoma with RNFLDs. The unilateral inferotemporal region (25.8%) was the most common location for RNFLDs, followed by the unilateral superotemporal region (24.4%). Multivariate analysis revealed that hypertension was more significantly associated (p = 0.048) with the bilateral superotemporal RNFLD group than with the bilateral inferotemporal RNFLD group. Conclusions: Superotemporal RNFLDs are more related to hypertension than are inferotemporal RNFLDs.

키워드

Hypertension Korea National Health and Nutrition Examination Survey Open-angle glaucoma Retinal nerve fiber layer defect