학술논문
Changes of Tear Film and Ocular Surface in Diabetes Mellitus
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- 영문명
- 발행기관
- 대한안과학회
- 저자명
- Kyung-Chul Yoon Seong-Kyu Im Man-Seong Seo
- 간행물 정보
- 『The Korean Journal of Ophthalmology』Vol.18 No.2, 168~174쪽, 전체 7쪽
- 주제분류
- 의약학 > 기타의약학
- 파일형태
- 발행일자
- 2004.08.30
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국문 초록
영문 초록
This study was performed to investigate the changes of tear film and ocular surface in diabetic patients, as well as the ocular and systemic factors related to these changes. We assessed the scoring of keratoepitheliopathy, corneal sensitivity test, tear film break-up time (BUT), Schirmer test, and conjunctival impression cytology in 94 eyes of 47 patients with noninsulin-dependent diabetes mellitus and in 60 eyes of 30 normal subjects. The degree of keratoepitheliopathy was severe, and the corneal sensitivity, BUT, and tear secretion were significantly reduced in the diabetic patients. Conjunctival impression cytology showed a higher grade of conjunctival squamous metaplasia and lower goblet cell density in the diabetic patients. All parameters were related to the status of metabolic control, diabetic neuropathy, and stage of diabetic retinopathy. We think that diabetic patients with poor metabolic
control, neuropathy, and advanced stage of retinopathy should be examined for tear film and ocular surface changes.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
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참고문헌
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