Intraocular Pressure Elevation after Intravitreal Triamcinolone Acetonide Injection

• 발행기관: 대한안과학회
• 저자명: Hye Young Park Kayoung Yi Ha Kyoung Kim
• 간행물 정보: 『The Korean Journal of Ophthalmology』Vol.19 No.2, 122~127쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.06.30

영문 초록

Purpose: This study investigated firstly the change of intraocular pressure (IOP) after injection of intravitreal triamcinolone acetonide (IVTA) for the treatment of macular edema and secondly the factors that influence these changes. Methods: A prospective, non-comparative study was performed in 60 patients at Kangnam Sacred Heart Hospital from October 2003 to September 2004. All the patients received 4-mg IVTA injection. Results: Mean IOP was elevated from the day after injection and peaked at 20.5 mmHg after 2 months(p=0.000). Twenty-six eyes (43.3%) showed significant IOP elevation. IOP was not controlled despite full glaucoma medication in 7 (11.7%) eyes. Two eyes underwent filtering surgery. Younger age was a statistically significant predictive factor for IOP elevation (p=0.009). Conclusions: In this study, patients who needed filtering surgery developed an IOP spike within one week after the injection. Therefore, clinicians should consider checking IOP at the end of the first week. Furthermore, greater cautions is mandatory with relatively younger patients. Korean Journal of Ophthalmology 19(2):122-127, 2005

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키워드

Intravitreal triamcinolone acetonide (IVTA) injection Intraocular pressure (IOP) Younger age